High circulating levels of the dengue virus nonstructural protein NS1 early in dengue illness correlate with the development of dengue hemorrhagic fever DH Libraty, PR Young, D Pickering, TP Endy, S Kalayanarooj, S Green, ... The Journal of infectious diseases 186 (8), 1165-1168, 2002 | 955 | 2002 |
An antigen capture enzyme-linked immunosorbent assay reveals high levels of the dengue virus protein NS1 in the sera of infected patients PR Young, PA Hilditch, C Bletchly, W Halloran Journal of clinical microbiology 38 (3), 1053-1057, 2000 | 719 | 2000 |
The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity M Beltramello, KL Williams, CP Simmons, A Macagno, L Simonelli, ... Cell host & microbe 8 (3), 271-283, 2010 | 702 | 2010 |
Immunolocalization of the dengue virus nonstructural glycoprotein NS1 suggests a role in viral RNA replication JM Mackenzie, MK Jones, PR Young Virology 220 (1), 232-240, 1996 | 639 | 1996 |
The flavivirus NS1 protein: molecular and structural biology, immunology, role in pathogenesis and application as a diagnostic biomarker DA Muller, PR Young Antiviral research 98 (2), 192-208, 2013 | 633 | 2013 |
Dengue virus NS1 protein activates cells via Toll-like receptor 4 and disrupts endothelial cell monolayer integrity N Modhiran, D Watterson, DA Muller, AK Panetta, DP Sester, L Liu, ... Science translational medicine 7 (304), 304ra142-304ra142, 2015 | 513 | 2015 |
Clinical and laboratory diagnosis of dengue virus infection DA Muller, ACI Depelsenaire, PR Young The Journal of infectious diseases 215 (suppl_2), S89-S95, 2017 | 484 | 2017 |
Retroviral invasion of the koala genome RE Tarlinton, J Meers, PR Young Nature 442 (7098), 79-81, 2006 | 436 | 2006 |
Activity of recombinant dengue 2 virus NS3 protease in the presence of a truncated NS2B co-factor, small peptide substrates, and inhibitors D Leung, K Schroder, H White, NX Fang, MJ Stoermer, G Abbenante, ... Journal of Biological Chemistry 276 (49), 45762-45771, 2001 | 406 | 2001 |
Maternal antibody and viral factors in the pathogenesis of dengue virus in infants CP Simmons, TNB Chau, TT Thuy, NM Tuan, DM Hoang, NT Thien, ... The Journal of infectious diseases 196 (3), 416-424, 2007 | 242 | 2007 |
The diagnostic sensitivity of dengue rapid test assays is significantly enhanced by using a combined antigen and antibody testing approach SR Fry, M Meyer, MG Semple, CP Simmons, SD Sekaran, JX Huang, ... PLoS neglected tropical diseases 5 (6), e1199, 2011 | 230 | 2011 |
Dengue virus nonstructural protein 1 is expressed in a glycosyl‐phosphatidylinositol‐linked form that is capable of signal transduction MG Jacobs, PJ Robinson, C Bletchly, JM Mackenzie, PR Young The FASEB Journal 14 (11), 1603-1610, 2000 | 224 | 2000 |
Wolbachia-mediated resistance to dengue virus infection and death at the cellular level FD Frentiu, J Robinson, PR Young, EA McGraw, SL O'Neill PloS one 5 (10), e13398, 2010 | 206 | 2010 |
Kinetics of plasma viremia and soluble nonstructural protein 1 concentrations in dengue: differential effects according to serotype and immune status HTL Duyen, TV Ngoc, DT Ha, VTT Hang, NTT Kieu, PR Young, JJ Farrar, ... Journal of Infectious Diseases 203 (9), 1292-1300, 2011 | 201 | 2011 |
The role of histidine residues in low-pH-mediated viral membrane fusion T Kampmann, DS Mueller, AE Mark, PR Young, B Kobe Structure 14 (10), 1481-1487, 2006 | 198 | 2006 |
Downsizing human, bacterial, and viral proteins to short water-stable alpha helices that maintain biological potency RS Harrison, NE Shepherd, HN Hoang, G Ruiz-Gómez, TA Hill, ... Proceedings of the National Academy of Sciences 107 (26), 11686-11691, 2010 | 197 | 2010 |
Real-time reverse transcriptase PCR for the endogenous koala retrovirus reveals an association between plasma viral load and neoplastic disease in koalas R Tarlinton, J Meers, J Hanger, P Young Journal of general virology 86 (3), 783-787, 2005 | 171 | 2005 |
Structure of West Nile virus NS3 protease: ligand stabilization of the catalytic conformation G Robin, K Chappell, MJ Stoermer, SH Hu, PR Young, DP Fairlie, ... Journal of molecular biology 385 (5), 1568-1577, 2009 | 168 | 2009 |
Use of recombinant fusion proteins and monoclonal antibodies to define linear and discontinuous antigenic sites on the dengue virus envelope glycoprotein F Megret, JP Hugnot, A Falconar, MK Gentry, DM Morens, JM Murray, ... Virology 187 (2), 480-491, 1992 | 163 | 1992 |
Viral bacterial co-infection of the respiratory tract during early childhood JC Brealey, PD Sly, PR Young, KJ Chappell FEMS microbiology letters 362 (10), fnv062, 2015 | 161 | 2015 |