A statistical thermodynamic model of the protein ensemble VJ Hilser, B García-Moreno E, TG Oas, G Kapp, ST Whitten Chemical reviews 106 (5), 1545-1558, 2006 | 235 | 2006 |
Local conformational fluctuations can modulate the coupling between proton binding and global structural transitions in proteins ST Whitten, B García-Moreno E, VJ Hilser Proceedings of the National Academy of Sciences 102 (12), 4282-4287, 2005 | 195 | 2005 |
pH dependence of stability of staphylococcal nuclease: evidence of substantial electrostatic interactions in the denatured state ST Whitten, B García-Moreno E Biochemistry 39 (46), 14292-14304, 2000 | 167 | 2000 |
The role of protein conformational fluctuations in allostery, function, and evolution JO Wrabl, J Gu, T Liu, TP Schrank, ST Whitten, VJ Hilser Biophysical chemistry 159 (1), 129-141, 2011 | 131 | 2011 |
Functional residues serve a dominant role in mediating the cooperativity of the protein ensemble T Liu, ST Whitten, VJ Hilser Proceedings of the National Academy of Sciences 104 (11), 4347-4352, 2007 | 87 | 2007 |
Low pH immobilizes and kills human leukocytes and prevents transmission of cell-associated HIV in a mouse model SS Olmsted, KV Khanna, EM Ng, ST Whitten, ON Johnson, RB Markham, ... BMC infectious diseases 5, 1-9, 2005 | 71 | 2005 |
The origin of pH-dependent changes in m-values for the denaturant-induced unfolding of proteins ST Whitten, JO Wooll, R Razeghifard, EB Garcı́a-Moreno, VJ Hilser Journal of molecular biology 309 (5), 1165-1175, 2001 | 70 | 2001 |
Ensemble‐based signatures of energy propagation in proteins: A new view of an old phenomenon T Liu, ST Whitten, VJ Hilser Proteins: Structure, Function, and Bioinformatics 62 (3), 728-738, 2006 | 62 | 2006 |
COREX/BEST server: a web browser-based program that calculates regional stability variations within protein structures J Vertrees, P Barritt, S Whitten, VJ Hilser Bioinformatics 21 (15), 3318-3319, 2005 | 62 | 2005 |
Thermodynamic mechanism and consequences of the polyproline II (PII) structural bias in the denatured states of proteins JB Hamburger, JC Ferreon, ST Whitten, VJ Hilser Biochemistry 43 (30), 9790-9799, 2004 | 55 | 2004 |
Temperature effects on the hydrodynamic radius of the intrinsically disordered N‐terminal region of the p53 protein TD Langridge, MJ Tarver, ST Whitten Proteins: Structure, Function, and Bioinformatics 82 (4), 668-678, 2014 | 53 | 2014 |
Revealing the nature of the native state ensemble through cold denaturation ST Whitten, AJ Kurtz, MS Pometun, AJ Wand, VJ Hilser Biochemistry 45 (34), 10163-10174, 2006 | 51 | 2006 |
Hydrodynamic radii of intrinsically disordered proteins determined from experimental polyproline II propensities ME Tomasso, MJ Tarver, D Devarajan, ST Whitten PLoS computational biology 12 (1), e1004686, 2016 | 45 | 2016 |
Molecular mechanisms of pH‐driven conformational transitions of proteins: Insights from continuum electrostatics calculations of acid unfolding CA Fitch, ST Whitten, VJ Hilser, B García‐Moreno E Proteins: Structure, Function, and Bioinformatics 63 (1), 113-126, 2006 | 45 | 2006 |
Fungal metabolite ophiobolin A as a promising anti-glioma agent: In vivo evaluation, structure–activity relationship and unique pyrrolylation of primary amines R Dasari, M Masi, R Lisy, M Ferdérin, LR English, A Cimmino, V Mathieu, ... Bioorganic & medicinal chemistry letters 25 (20), 4544-4548, 2015 | 43 | 2015 |
Alanine and proline content modulate global sensitivity to discrete perturbations in disordered proteins RB Perez, A Tischer, M Auton, ST Whitten Proteins: Structure, Function, and Bioinformatics 82 (12), 3373-3384, 2014 | 37 | 2014 |
B.: pH dependence of stability of staphylococcal nuclease: Evidence of substantial electrostatic interactions in the denatured state ST Whitten, E García-Moreno Biochemistry 39 (14), 292-14, 2000 | 31 | 2000 |
Intrinsically disordered regions that drive phase separation form a robustly distinct protein class AI Ibrahim, N Khaodeuanepheng, D Amarasekara, JJ Correia, K Lewis, ... Biophysical Journal 122 (3), 207a, 2023 | 30 | 2023 |
The proline/glycine-rich region of the biofilm adhesion protein Aap forms an extended stalk that resists compaction AE Yarawsky, LR English, ST Whitten, AB Herr Journal of molecular biology 429 (2), 261-279, 2017 | 29 | 2017 |
Denatured-state energy landscapes of a protein structural database reveal the energetic determinants of a framework model for folding S Wang, J Gu, SA Larson, ST Whitten, VJ Hilser Journal of molecular biology 381 (5), 1184-1201, 2008 | 28 | 2008 |