| Minocycline attenuates mechanical allodynia and proinflammatory cytokine expression in rat models of pain facilitation A Ledeboer, EM Sloane, ED Milligan, MG Frank, JH Mahony, SF Maier, ... Pain 115 (1-2), 71-83, 2005 | 820 | 2005 |
| Glia as the “bad guys”: implications for improving clinical pain control and the clinical utility of opioids LR Watkins, MR Hutchinson, A Ledeboer, J Wieseler-Frank, ED Milligan, ... Brain, behavior, and immunity 21 (2), 131-146, 2007 | 444 | 2007 |
| Intrathecal interleukin-10 gene therapy attenuates paclitaxel-induced mechanical allodynia and proinflammatory cytokine expression in dorsal root ganglia in rats A Ledeboer, BM Jekich, EM Sloane, JH Mahoney, SJ Langer, ED Milligan, ... Brain, behavior, and immunity 21 (5), 686-698, 2007 | 349 | 2007 |
| Interleukin‐10, interleukin‐4, and transforming growth factor‐β differentially regulate lipopolysaccharide‐induced production of pro‐inflammatory cytokines and nitric oxide in … A Ledeboer, JJP Brevé, S Poole, FJH Tilders, AM Van Dam Glia 30 (2), 134-142, 2000 | 300 | 2000 |
| Expression and regulation of interleukin‐10 and interleukin‐10 receptor in rat astroglial and microglial cells A Ledeboer, JJP Brevé, A Wierinckx, S Van Der Jagt, AF Bristow, ... European journal of neuroscience 16 (7), 1175-1185, 2002 | 246 | 2002 |
| Ibudilast (AV-411) a new class therapeutic candidate for neuropathic pain and opioid withdrawal syndromes A Ledeboer, MR Hutchinson, LR Watkins, KW Johnson Expert opinion on investigational drugs 16 (7), 935-950, 2007 | 188 | 2007 |
| Involvement of spinal cord nuclear factor κB activation in rat models of proinflammatory cytokine‐mediated pain facilitation A Ledeboer, M Gamanos, W Lai, D Martin, SF Maier, LR Watkins, N Quan European Journal of Neuroscience 22 (8), 1977-1986, 2005 | 176 | 2005 |
| The glial modulatory drug AV411 attenuates mechanical allodynia in rat models of neuropathic pain A Ledeboer, T Liu, JA Shumilla, JH Mahoney, S Vijay, MI Gross, ... Neuron glia biology 2 (4), 279-291, 2006 | 147 | 2006 |
| Anti-inflammatory cytokine gene therapy decreases sensory and motor dysfunction in experimental Multiple Sclerosis: MOG-EAE behavioral and anatomical symptom treatment with … E Sloane, A Ledeboer, W Seibert, B Coats, M Van Strien, SF Maier, ... Brain, behavior, and immunity 23 (1), 92-100, 2009 | 125 | 2009 |
| Site-specific modulation of LPS-induced fever and interleukin-1β expression in rats by interleukin-10 A Ledeboer, R Binnekade, JJP Brevé, JGJM Bol, FJH Tilders, ... American Journal of Physiology-Regulatory, Integrative and Comparative …, 2002 | 86 | 2002 |
| Interleukin-6 mediates low-threshold mechanical allodynia induced by intrathecal HIV-1 envelope glycoprotein gp120 DK Schoeniger-Skinner, A Ledeboer, MG Frank, ED Milligan, S Poole, ... Brain, behavior, and immunity 21 (5), 660-667, 2007 | 84 | 2007 |
| Regional and temporal expression patterns of interleukin-10, interleukin-10 receptor and adhesion molecules in the rat spinal cord during chronic relapsing EAE A Ledeboer, A Wierinckx, JGJM Bol, S Floris, CR de Lavalette, ... Journal of neuroimmunology 136 (1-2), 94-103, 2003 | 62 | 2003 |
| Spinal cord glia and interleukin-1 do not appear to mediate persistent allodynia induced by intramuscular acidic saline in rats A Ledeboer, JH Mahoney, ED Milligan, D Martin, SF Maier, LR Watkins The journal of pain 7 (10), 757-767, 2006 | 55 | 2006 |
| The Brown Norway rat displays enhanced stress-induced ACTH reactivity at day 18 after 24-h maternal deprivation at day 3 JO Workel, MS Oitzl, A Ledeboer, ER de Kloet Developmental brain research 103 (2), 199-203, 1997 | 50 | 1997 |
| A role for G protein‐coupled receptor kinase 2 in mechanical allodynia W Kleibeuker, A Ledeboer, N Eijkelkamp, LR Watkins, SF Maier, J Zijlstra, ... European Journal of Neuroscience 25 (6), 1696-1704, 2007 | 46 | 2007 |
| Persistent repression of tau in the brain using engineered zinc finger protein transcription factors S Wegmann, SL DeVos, B Zeitler, K Marlen, RE Bennett, M Perez-Rando, ... Science Advances 7 (12), eabe1611, 2021 | 40 | 2021 |
| AAV2/6 gene therapy in a murine model of Fabry disease results in supraphysiological enzyme activity and effective substrate reduction M Yasuda, MW Huston, S Pagant, L Gan, SS Martin, S Sproul, D Richards, ... Molecular therapy Methods & clinical development 18, 607-619, 2020 | 36 | 2020 |
| Substituted pyrazolo [1, 5-a] pyridine compounds having multi-target activity FCA Gaeta, KW Johnson, MI Gross, A Ledeboer US Patent App. 12/796,164, 2011 | 18 | 2011 |
| Clinical enrollment assay to detect preexisting neutralizing antibodies to AAV6 with demonstrated transgene expression in gene therapy trials L Cao, A Ledeboer, Y Pan, Y Lu, K Meyer Gene Therapy 30 (1), 150-159, 2023 | 9 | 2023 |
| Neuroimmune interactions and pain: the role of immune and glial cells LR WATKINS, J WIESELER-FRANK, MR HUTCHINSON, A LEDEBOER, ... Psychoneuroimmunology, 393-414, 2007 | 7 | 2007 |
