BRAF inhibitors in thyroid cancer: clinical impact, mechanisms of resistance and future perspectives F Crispo, T Notarangelo, M Pietrafesa, G Lettini, G Storto, A Sgambato, ... Cancers 11 (9), 1388, 2019 | 89 | 2019 |
HSP90 molecular chaperones, metabolic rewiring, and epigenetics: impact on tumor progression and perspective for anticancer therapy V Condelli, F Crispo, M Pietrafesa, G Lettini, DS Matassa, F Esposito, ... Cells 8 (6), 532, 2019 | 82 | 2019 |
Resistance to paclitxel in breast carcinoma cells requires a quality control of mitochondrial antiapoptotic proteins by TRAP1 F Maddalena, L Sisinni, G Lettini, V Condelli, DS Matassa, A Piscazzi, ... Molecular oncology 7 (5), 895-906, 2013 | 82 | 2013 |
TRAP1 revisited: novel localizations and functions of a ‘next-generation’biomarker MR Amoroso, DS Matassa, L Sisinni, G Lettini, M Landriscina, F Esposito International Journal of Oncology 45 (3), 969-977, 2014 | 51 | 2014 |
TRAP1 regulates stemness through Wnt/β-catenin pathway in human colorectal carcinoma G Lettini, L Sisinni, V Condelli, DS Matassa, V Simeon, F Maddalena, ... Cell Death & Differentiation 23 (11), 1792-1803, 2016 | 50 | 2016 |
TRAP1 downregulation in human ovarian cancer enhances invasion and epithelial–mesenchymal transition MR Amoroso, DS Matassa, I Agliarulo, R Avolio, H Lu, L Sisinni, G Lettini, ... Cell Death & Disease 7 (12), e2522-e2522, 2016 | 48 | 2016 |
TRAP1 is involved in BRAF regulation and downstream attenuation of ERK phosphorylation and cell-cycle progression: a novel target for BRAF-mutated colorectal tumors V Condelli, A Piscazzi, L Sisinni, DS Matassa, F Maddalena, G Lettini, ... Cancer research 74 (22), 6693-6704, 2014 | 42 | 2014 |
TRAP1 controls cell cycle G2–M transition through the regulation of CDK1 and MAD2 expression/ubiquitination L Sisinni, F Maddalena, V Condelli, G Pannone, V Simeon, V Li Bergolis, ... The Journal of Pathology 243 (1), 123-134, 2017 | 39 | 2017 |
TRAP1: a viable therapeutic target for future cancer treatments? G Lettini, F Maddalena, L Sisinni, V Condelli, DS Matassa, MP Costi, ... Expert Opinion on Therapeutic Targets 21 (8), 805-815, 2017 | 38 | 2017 |
Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma V Condelli, F Maddalena, L Sisinni, G Lettini, DS Matassa, A Piscazzi, ... Oncotarget 6 (26), 22298, 2015 | 35 | 2015 |
TRAP1 role in endoplasmic reticulum stress protection favors resistance to anthracyclins in breast carcinoma cells L Sisinni, F Maddalena, G Lettini, V Condelli, DS Matassa, F Esposito, ... International Journal of Oncology 44 (2), 573-582, 2014 | 30 | 2014 |
Evaluation of glucose uptake in normal and cancer cell lines by positron emission tomography F Maddalena, G Lettini, R Gallicchio, L Sisinni, V Simeon, A Nardelli, ... Molecular imaging 14 (9), 7290.2015. 00021, 2015 | 28 | 2015 |
TRAP1 protein signature predicts outcome in human metastatic colorectal carcinoma F Maddalena, V Simeon, G Vita, A Bochicchio, L Possidente, L Sisinni, ... Oncotarget 8 (13), 21229, 2017 | 27 | 2017 |
TRAP1 enhances Warburg metabolism through modulation of PFK1 expression/activity and favors resistance to EGFR inhibitors in human colorectal carcinomas F Maddalena, V Condelli, DS Matassa, C Pacelli, R Scrima, G Lettini, ... Molecular Oncology 14 (12), 3030-3047, 2020 | 26 | 2020 |
New TRAP1 and Hsp90 chaperone inhibitors with cationic components: Preliminary studies on mitochondrial targeting R Rondanin, G Lettini, P Oliva, R Baruchello, C Costantini, C Trapella, ... Bioorganic & Medicinal Chemistry Letters 28 (13), 2289-2293, 2018 | 19 | 2018 |
Validation of vacuum-based refrigerated system for biobanking tissue preservation: analysis of cellular morphology, protein stability, and RNA quality V Condelli, G Lettini, G Patitucci, F D'Auria, M D'Amico, G Vita, P Musto, ... Biopreservation and biobanking 12 (1), 35-45, 2014 | 18 | 2014 |
TRAP1 regulates Wnt/β-catenin pathway through LRP5/6 receptors expression modulation G Lettini, V Condelli, M Pietrafesa, F Crispo, P Zoppoli, F Maddalena, ... International journal of molecular sciences 21 (20), 7526, 2020 | 13 | 2020 |
F-18 FDG PET/CT in the assessment of patients with unexplained CEA rise after surgical curative resection for colorectal cancer S Giacomobono, R Gallicchio, D Capacchione, A Nardelli, D Gattozzi, ... International journal of colorectal disease 28, 1699-1705, 2013 | 12 | 2013 |
Heat shock proteins in cancer stem cell maintenance: A potential therapeutic target? G Lettini, S Lepore, F Crispo, L Sisinni, F Esposito, M Landriscina Universidad de Murcia, Departamento de Biologia Celular e Histiologia, 2020 | 10 | 2020 |
comparative gene expression profiling of tobacco-associated HPV-positive versus negative oral squamous carcinoma cell lines S Lepore, G Lettini, V Condelli, L Sisinni, A Piscazzi, V Simeon, P Zoppoli, ... International Journal of Medical Sciences 17 (1), 112, 2020 | 7 | 2020 |