Epigenetic signatures of gestational diabetes mellitus on cord blood methylation L Haertle, N El Hajj, M Dittrich, T Müller, I Nanda, H Lehnen, T Haaf Clinical epigenetics 9, 1-11, 2017 | 121 | 2017 |
DNA methylation signatures in cord blood of ICSI children N El Hajj, L Haertle, M Dittrich, S Denk, H Lehnen, T Hahn, M Schorsch, ... Human Reproduction 32 (8), 1761-1769, 2017 | 98 | 2017 |
IKZF1/3 and CRL4CRBN E3 ubiquitin ligase mutations and resistance to immunomodulatory drugs in multiple myeloma S Barrio, U Munawar, YX Zhu, N Giesen, CX Shi, M Da Viá, R Sanchez, ... Haematologica 105 (5), e237, 2020 | 59 | 2020 |
CIC Mutation as a Molecular Mechanism of Acquired Resistance to Combined BRAF‐MEK Inhibition in Extramedullary Multiple Myeloma with Central Nervous … MC Da Vià, AG Solimando, A Garitano‐Trojaola, S Barrio, U Munawar, ... The oncologist 25 (2), 112-118, 2020 | 48 | 2020 |
Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice DF De Jesus, K Orime, D Kaminska, T Kimura, G Basile, CH Wang, ... The Journal of clinical investigation 130 (5), 2391-2407, 2020 | 44 | 2020 |
Single-and double-hit events in genes encoding immune targets before and after T cell–engaging antibody therapy in MM MS Truger, J Duell, X Zhou, L Heimeshoff, A Ruckdeschel, M John, ... Blood advances 5 (19), 3794-3798, 2021 | 40 | 2021 |
Cereblon enhancer methylation and IMiD resistance in multiple myeloma L Haertle, S Barrio, U Munawar, S Han, X Zhou, C Vogt, RA Fernández, ... Blood, The Journal of the American Society of Hematology 138 (18), 1721-1726, 2021 | 36 | 2021 |
Exposure to Gestational Diabetes Mellitus (GDM) alters DNA methylation in placenta and fetal cord blood Z Awamleh, DT Butcher, A Hanley, R Retnakaran, L Haertle, T Haaf, ... Diabetes Research and Clinical Practice 174, 108690, 2021 | 34 | 2021 |
Allele-specific methylation of imprinted genes in fetal cord blood is influenced by cis-acting genetic variants and parental factors R Potabattula, M Dittrich, J Böck, L Haertle, T Müller, T Hahn, M Schorsch, ... Epigenomics 10 (10), 1315-1326, 2018 | 24 | 2018 |
Actin cytoskeleton deregulation confers midostaurin resistance in FLT3-mutant acute myeloid leukemia A Garitano-Trojaola, A Sancho, R Götz, P Eiring, S Walz, H Jetani, ... Communications Biology 4 (1), 799, 2021 | 23 | 2021 |
Single CpG hypermethylation, allele methylation errors, and decreased expression of multiple tumor suppressor genes in normal body cells of mutation‐negative early‐onset and … J Böck, S Appenzeller, L Haertle, T Schneider, A Gehrig, J Schröder, ... International journal of cancer 143 (6), 1416-1425, 2018 | 23 | 2018 |
Hypermethylation of the non-imprinted maternal MEG3 and paternal MEST alleles is highly variable among normal individuals L Haertle, A Maierhofer, J Böck, H Lehnen, Y Böttcher, M Blüher, ... PLoS One 12 (8), e0184030, 2017 | 19 | 2017 |
Methylomic profiling in trisomy 21 identifies cognition-and Alzheimer’s disease-related dysregulation L Haertle, T Müller, R Lardenoije, A Maierhofer, M Dittrich, RJM Riemens, ... Clinical epigenetics 11, 1-11, 2019 | 18 | 2019 |
All-trans retinoic acid works synergistically with the γ-secretase inhibitor crenigacestat to augment BCMA on multiple myeloma and the efficacy of BCMA-CAR T cells E García-Guerrero, LG Rodríguez-Lobato, B Sierro-Martínez, S Danhof, ... Haematologica 108 (2), 568, 2023 | 10 | 2023 |
Hierarchy of mono- and biallelic TP53 alterations in multiple myeloma cell fitness U Munawar, L Rasche, N Müller, C Vogt, M Da-Via, L Haertle, ... Blood, The Journal of the American Society of Hematology 134 (10), 836-840, 2019 | 10 | 2019 |
Single-nucleotide variants and epimutations induce proteasome inhibitor resistance in multiple myeloma L Haertle, S Barrio, U Munawar, S Han, X Zhou, M Simicek, C Vogt, ... Clinical Cancer Research 29 (1), 279-288, 2023 | 8 | 2023 |
The link between cytogenetics/genomics and imaging patterns of relapse and progression in patients with relapsed/refractory multiple myeloma: a pilot study utilizing 18F-FDG PET/CT X Zhou, A Dierks, O Kertels, S Samnick, M Kircher, AK Buck, L Haertle, ... Cancers 12 (9), 2399, 2020 | 7 | 2020 |
Mechanisms of proteasome inhibitor resistance selected by clonal evolution in multiple myeloma L Haertle, S Barrio, M Simicek, U Munawar, R Sanchez, M Bittrich, ... Blood 134, 4349, 2019 | 6 | 2019 |
Genetic alterations in members of the proteasome 26S subunit, AAA-ATPase (PSMC) gene family in the light of proteasome inhibitor resistance in multiple myeloma L Haertle, N Buenache, HN Cuesta Hernández, M Simicek, R Snaurova, ... Cancers 15 (2), 532, 2023 | 5 | 2023 |
Advanced risk stratification in multiple myeloma beyond traditional FISH: the first prospective real-world evidence for SKY92 gene expression profiling X Zhou, A Hofmann, C Vogt, S Nerreter, E Teufel, E Stanojkovska, ... Blood 140 (Supplement 1), 4273-4274, 2022 | 4 | 2022 |