| Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation MP Tariq Afroz, Eva-Maria Hock, Patrick Ernst, Chiara Foglieni, Melanie ... Nature Communications 8, 2017 | 278 | 2017 |
| Reprogramming Bacteriophage Host Range through Structure-Guided Design of Chimeric Receptor Binding Proteins M Dunne, B Rupf, M Tala, X Qabrati, P Ernst, Y Shen, E Sumrall, L Heeb, ... Cell reports 29 (5), 1336-1350. e4, 2019 | 168 | 2019 |
| Adenoviral vector with shield and adapter increases tumor specificity and escapes liver and immune control M Schmid, P Ernst, A Honegger, M Suomalainen, M Zimmermann, ... Nature communications 9 (1), 450, 2018 | 80 | 2018 |
| Design and applications of a clamp for Green Fluorescent Protein with picomolar affinity S Hansen, JC Stüber, P Ernst, A Koch, D Bojar, A Batyuk, A Plückthun Scientific reports 7 (1), 16292, 2017 | 58 | 2017 |
| Gilhespy LAB, Laferriere F, Maniecka Z, Plückthun A, Mittl P et al (2017) Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic … T Afroz, EM Hock, P Ernst, C Foglieni, M Jambeau Nat Commun 8 (45), 536-543, 2017 | 58 | 2017 |
| Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism M Deluigi, A Klipp, C Klenk, L Merklinger, SA Eberle, L Morstein, P Heine, ... Science Advances 7 (5), eabe5504, 2021 | 35 | 2021 |
| Engineering an anti-HER2 biparatopic antibody with a multimodal mechanism of action F Kast, M Schwill, JC Stüber, S Pfundstein, G Nagy-Davidescu, ... Nature Communications 12 (1), 3790, 2021 | 34 | 2021 |
| Chaperone-assisted structure elucidation with DARPins PRE Mittl, P Ernst, A Plückthun Current Opinion in Structural Biology 60, 93-100, 2020 | 29 | 2020 |
| Structural analysis of biological targets by host: guest crystal lattice engineering P Ernst, A Plückthun, PRE Mittl Scientific reports 9 (1), 1-11, 2019 | 22 | 2019 |
| Computationally Designed Armadillo Repeat Proteins for Modular Peptide Recognition C Reichen, S Hansen, C Forzani, A Honegger, SJ Fleishman, T Zhou, ... Journal of Molecular Biology 428 (22), 4467-4489, 2016 | 22 | 2016 |
| Advances in the design and engineering of peptide-binding repeat proteins P Ernst, A Plückthun Biological chemistry 398 (1), 23-29, 2017 | 18 | 2017 |
| Curvature of designed armadillo repeat proteins allows modular peptide binding AP Simon Hansen, Patrick Ernst, Sebastian LB König, Christian Reichen ... Journal of Structural Biology, 2017 | 15* | 2017 |
| An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture M ElGamacy, M Coles, P Ernst, H Zhu, MD Hartmann, A Plückthun, ... ACS synthetic biology 7 (9), 2226-2235, 2018 | 13 | 2018 |
| Rigid fusions of designed helical repeat binding proteins efficiently protect a binding surface from crystal contacts P Ernst, A Honegger, F van der Valk, C Ewald, PRE Mittl, A Plückthun Scientific reports 9 (1), 16162, 2019 | 10 | 2019 |
| Distinct conformations of the HIV-1 V3 loop crown are targetable for broad neutralization N Friedrich, E Stiegeler, M Glögl, T Lemmin, S Hansen, C Kadelka, Y Wu, ... Nature Communications 12 (1), 6705, 2021 | 9 | 2021 |
| Structure-Guided Design of a Peptide Lock for Modular Peptide Binders P Ernst, F Zosel, C Reichen, D Nettels, B Schuler, A Plückthun ACS Chemical Biology 15 (2), 457-468, 2020 | 9 | 2020 |
| Functional and dynamic polymerization of the ALS-linked protein TDP-43 antagonizes its pathologic aggregation. Nat Commun 8 (1): 45 T Afroz, EM Hock, P Ernst, C Foglieni, M Jambeau, L Gilhespy, ... | 8 | 2017 |
| The M23 peptidase domain of the Staphylococcal phage 2638A endolysin M Dunne, P Ernst, A Sobieraj, A Pluckthun, MJ Loessner (No Title), 2020 | 2 | 2020 |
| Unexpected dynamics in femtomolar complexes of binding proteins with peptides S Cucuzza, M Sitnik, S Jurt, E Michel, W Dai, T Müntener, P Ernst, ... Nature communications 14 (1), 7823, 2023 | 1 | 2023 |
| Modular binder technology by NGS-aided, high-resolution selection in yeast of designed armadillo modules Y Stark, F Menard, JR Jeliazkov, P Ernst, A Chembath, M Ashraf, AV Hine, ... Proceedings of the National Academy of Sciences 121 (27), e2318198121, 2024 | | 2024 |
Andreas PluckthunBiochemisches Institut, Universität Zürich在 bioc.uzh.ch 的电子邮件经过验证
