Focal adhesion kinase is upstream of phosphatidylinositol 3-kinase/Akt in regulating fibroblast survival in response to contraction of type I collagen matrices via a β1 … H Xia, RS Nho, J Kahm, J Kleidon, CA Henke Journal of Biological Chemistry 279 (31), 33024-33034, 2004 | 410 | 2004 |
The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14 JM Park, CH Jung, M Seo, NM Otto, D Grunwald, KH Kim, B Moriarity, ... Autophagy 12 (3), 547-564, 2016 | 313 | 2016 |
Pathological integrin signaling enhances proliferation of primary lung fibroblasts from patients with idiopathic pulmonary fibrosis H Xia, D Diebold, R Nho, D Perlman, J Kleidon, J Kahm, S Avdulov, ... The Journal of experimental medicine 205 (7), 1659-1672, 2008 | 256 | 2008 |
FoxO3a and disease progression RS Nho, P Hergert World journal of biological chemistry 5 (3), 346, 2014 | 179 | 2014 |
The role of the mammalian target of rapamycin (mTOR) in pulmonary fibrosis J Lawrence, R Nho International journal of molecular sciences 19 (3), 778, 2018 | 173 | 2018 |
Fibrotic myofibroblasts manifest genome-wide derangements of translational control O Larsson, D Diebold, D Fan, M Peterson, RS Nho, PB Bitterman, ... PloS one 3 (9), e3220, 2008 | 129 | 2008 |
Role of integrin-linked kinase in regulating phosphorylation of Akt and fibroblast survival in type I collagen matrices through a β1 integrin viability signaling pathway RS Nho, H Xia, J Kahm, J Kleidon, D Diebold, CA Henke Journal of Biological Chemistry 280 (28), 26630-26639, 2005 | 124 | 2005 |
Advanced therapeutic strategies for chronic lung disease using nanoparticle-based drug delivery JY Yhee, J Im, RS Nho Journal of clinical medicine 5 (9), 82, 2016 | 122 | 2016 |
Pathological alteration of FoxO3a activity promotes idiopathic pulmonary fibrosis fibroblast proliferation on type i collagen matrix RS Nho, P Hergert, J Kahm, J Jessurun, C Henke The American journal of pathology 179 (5), 2420-2430, 2011 | 109 | 2011 |
IPF fibroblasts are desensitized to type I collagen matrix-induced cell death by suppressing low autophagy via aberrant Akt/mTOR kinases RS Nho, P Hergert PloS one 9 (4), e94616, 2014 | 104 | 2014 |
Survivin expression induced by endothelin-1 promotes myofibroblast resistance to apoptosis JC Horowitz, IO Ajayi, P Kulasekaran, DS Rogers, JB White, ... The international journal of biochemistry & cell biology 44 (1), 158-169, 2012 | 91 | 2012 |
Reduced FoxO3a expression causes low autophagy in idiopathic pulmonary fibrosis fibroblasts on collagen matrices J Im, P Hergert, RS Nho American Journal of Physiology-Lung Cellular and Molecular Physiology 309 (6 …, 2015 | 86 | 2015 |
FoxO3a (Forkhead Box O3a) deficiency protects Idiopathic Pulmonary Fibrosis (IPF) fibroblasts from type I polymerized collagen matrix-induced apoptosis via caveolin-1 (cav-1 … RS Nho, M Peterson, P Hergert, CA Henke PloS one 8 (4), e61017, 2013 | 85 | 2013 |
Pathological effects of nano-sized particles on the respiratory system R Nho Nanomedicine: Nanotechnology, Biology and Medicine 29, 102242, 2020 | 78 | 2020 |
Hyaluronan‐CD44/RHAMM interaction‐dependent cell proliferation and survival in lung cancer cells JM Song, J Im, RS Nho, YH Han, P Upadhyaya, F Kassie Molecular carcinogenesis 58 (3), 321-333, 2019 | 77 | 2019 |
MicroRNA-96 inhibits FoxO3a function in IPF fibroblasts on type I collagen matrix RS Nho, J Im, YY Ho, P Hergert American Journal of Physiology-Lung Cellular and Molecular Physiology 307 (8 …, 2014 | 62 | 2014 |
Low α2β1 integrin function enhances the proliferation of fibroblasts from patients with idiopathic pulmonary fibrosis by activation of the β-catenin pathway H Xia, J Seeman, J Hong, P Hergert, V Bodem, J Jessurun, K Smith, ... The American journal of pathology 181 (1), 222-233, 2012 | 60 | 2012 |
PTEN regulates fibroblast elimination during collagen matrix contraction RS Nho, H Xia, D Diebold, J Kahm, J Kleidon, E White, CA Henke Journal of Biological Chemistry 281 (44), 33291-33301, 2006 | 58 | 2006 |
FoxM1-dependent RAD51 and BRCA2 signaling protects idiopathic pulmonary fibrosis fibroblasts from radiation-induced cell death J Im, J Lawrence, D Seelig, RS Nho Cell Death & Disease 9 (6), 584, 2018 | 50 | 2018 |
Idiopathic pulmonary fibrosis fibroblasts become resistant to Fas ligand‐dependent apoptosis via the alteration of decoy receptor 3 J Im, K Kim, P Hergert, RS Nho The Journal of pathology 240 (1), 25-37, 2016 | 49 | 2016 |