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Kaid C. Harper
Kaid C. Harper
在 abbvie.com 的电子邮件经过验证
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引用次数
引用次数
年份
The development of multidimensional analysis tools for asymmetric catalysis and beyond
MS Sigman, KC Harper, EN Bess, A Milo
Accounts of chemical research 49 (6), 1292-1301, 2016
3612016
Multidimensional steric parameters in the analysis of asymmetric catalytic reactions
KC Harper, EN Bess, MS Sigman
Nature chemistry 4 (5), 366-374, 2012
2812012
Macrocyclic bis-thioureas catalyze stereospecific glycosylation reactions
Y Park, KC Harper, N Kuhl, EE Kwan, RY Liu, EN Jacobsen
Science 355 (6321), 162-166, 2017
2492017
Three-dimensional correlation of steric and electronic free energy relationships guides asymmetric propargylation
KC Harper, MS Sigman
Science 333 (6051), 1875-1878, 2011
2162011
A laser driven flow chemistry platform for scaling photochemical reactions with visible light
KC Harper, EG Moschetta, SV Bordawekar, SJ Wittenberger
ACS central science 5 (1), 109-115, 2019
1592019
Using physical organic parameters to correlate asymmetric catalyst performance
KC Harper, MS Sigman
The Journal of Organic Chemistry 78 (7), 2813-2818, 2013
1052013
Predicting and optimizing asymmetric catalyst performance using the principles of experimental design and steric parameters
KC Harper, MS Sigman
Proceedings of the National Academy of Sciences 108 (6), 2179-2183, 2011
932011
Prediction of catalyst and substrate performance in the enantioselective propargylation of aliphatic ketones by a multidimensional model of steric effects
KC Harper, SC Vilardi, MS Sigman
Journal of the American Chemical Society 135 (7), 2482-2485, 2013
912013
Overcoming the limitations of Kolbe coupling with waveform-controlled electrosynthesis
Y Hioki, M Costantini, J Griffin, KC Harper, MP Merini, B Nissl, ...
Science 380 (6640), 81-87, 2023
742023
Chemoselective (hetero) arene electroreduction enabled by rapid alternating polarity
K Hayashi, J Griffin, KC Harper, Y Kawamata, PS Baran
Journal of the American Chemical Society 144 (13), 5762-5768, 2022
702022
Electrochemical PINOylation of methylarenes: improving the scope and utility of benzylic oxidation through mediated electrolysis
MA Hoque, J Twilton, J Zhu, MD Graaf, KC Harper, E Tuca, GA DiLabio, ...
Journal of the American Chemical Society 144 (33), 15295-15302, 2022
412022
Phase-transfer-catalyzed asymmetric acylimidazole alkylation
MB Andrus, MA Christiansen, EJ Hicken, MJ Gainer, DK Bedke, ...
Organic Letters 9 (23), 4865-4868, 2007
352007
Scalable flow electrochemical alcohol oxidation: maintaining high stereochemical fidelity in the synthesis of levetiracetam
X Zhong, MA Hoque, MD Graaf, KC Harper, F Wang, JD Genders, ...
Organic process research & development 25 (12), 2601-2607, 2021
342021
Commercial-Scale Visible Light Trifluoromethylation of 2-Chlorothiophenol Using CF3I Gas
KC Harper, EX Zhang, ZQ Liu, T Grieme, TB Towne, DJ Mack, J Griffin, ...
Organic Process Research & Development 26 (2), 404-412, 2022
262022
Phase-transfer catalyzed asymmetric arylacetate alkylation
MB Andrus, KC Harper, MA Christiansen, MA Binkley
Tetrahedron Letters 50 (31), 4541-4544, 2009
232009
Scalable electrochemical decarboxylative olefination driven by alternating polarity
AF Garrido‐Castro, Y Hioki, Y Kusumoto, K Hayashi, J Griffin, KC Harper, ...
Angewandte Chemie International Edition 62 (42), e202309157, 2023
222023
Silanediol anion binding and enantioselective catalysis
JW Attard, K Osawa, Y Guan, J Hatt, S Kondo, A Mattson
Synthesis 51 (10), 2107-2115, 2019
222019
Emerging reaction technologies in pharmaceutical development: Challenges and opportunities in electrochemistry, photochemistry, and biocatalysis
B Cohen, D Lehnherr, M Sezen-Edmonds, JH Forstater, MO Frederick, ...
Chemical Engineering Research and Design 192, 622-637, 2023
182023
Expanding the repertoire for “large small molecules”: prodrug ABBV-167 efficiently converts to venetoclax with reduced food effect in healthy volunteers
AH Salem, ZF Tao, OF Bueno, J Chen, S Chen, R Edalji, SW Elmore, ...
Molecular Cancer Therapeutics 20 (6), 999-1008, 2021
152021
Sequential Reduction of Nitroalkanes Mediated by CS2 and Amidine/Guanidine Bases: A Controllable Nef Reaction
M Ju, W Guan, JM Schomaker, KC Harper
Organic letters 21 (22), 8893-8898, 2019
122019
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