The development of multidimensional analysis tools for asymmetric catalysis and beyond MS Sigman, KC Harper, EN Bess, A Milo Accounts of chemical research 49 (6), 1292-1301, 2016 | 361 | 2016 |
Multidimensional steric parameters in the analysis of asymmetric catalytic reactions KC Harper, EN Bess, MS Sigman Nature chemistry 4 (5), 366-374, 2012 | 281 | 2012 |
Macrocyclic bis-thioureas catalyze stereospecific glycosylation reactions Y Park, KC Harper, N Kuhl, EE Kwan, RY Liu, EN Jacobsen Science 355 (6321), 162-166, 2017 | 249 | 2017 |
Three-dimensional correlation of steric and electronic free energy relationships guides asymmetric propargylation KC Harper, MS Sigman Science 333 (6051), 1875-1878, 2011 | 216 | 2011 |
A laser driven flow chemistry platform for scaling photochemical reactions with visible light KC Harper, EG Moschetta, SV Bordawekar, SJ Wittenberger ACS central science 5 (1), 109-115, 2019 | 159 | 2019 |
Using physical organic parameters to correlate asymmetric catalyst performance KC Harper, MS Sigman The Journal of Organic Chemistry 78 (7), 2813-2818, 2013 | 105 | 2013 |
Predicting and optimizing asymmetric catalyst performance using the principles of experimental design and steric parameters KC Harper, MS Sigman Proceedings of the National Academy of Sciences 108 (6), 2179-2183, 2011 | 93 | 2011 |
Prediction of catalyst and substrate performance in the enantioselective propargylation of aliphatic ketones by a multidimensional model of steric effects KC Harper, SC Vilardi, MS Sigman Journal of the American Chemical Society 135 (7), 2482-2485, 2013 | 91 | 2013 |
Overcoming the limitations of Kolbe coupling with waveform-controlled electrosynthesis Y Hioki, M Costantini, J Griffin, KC Harper, MP Merini, B Nissl, ... Science 380 (6640), 81-87, 2023 | 74 | 2023 |
Chemoselective (hetero) arene electroreduction enabled by rapid alternating polarity K Hayashi, J Griffin, KC Harper, Y Kawamata, PS Baran Journal of the American Chemical Society 144 (13), 5762-5768, 2022 | 70 | 2022 |
Electrochemical PINOylation of methylarenes: improving the scope and utility of benzylic oxidation through mediated electrolysis MA Hoque, J Twilton, J Zhu, MD Graaf, KC Harper, E Tuca, GA DiLabio, ... Journal of the American Chemical Society 144 (33), 15295-15302, 2022 | 41 | 2022 |
Phase-transfer-catalyzed asymmetric acylimidazole alkylation MB Andrus, MA Christiansen, EJ Hicken, MJ Gainer, DK Bedke, ... Organic Letters 9 (23), 4865-4868, 2007 | 35 | 2007 |
Scalable flow electrochemical alcohol oxidation: maintaining high stereochemical fidelity in the synthesis of levetiracetam X Zhong, MA Hoque, MD Graaf, KC Harper, F Wang, JD Genders, ... Organic process research & development 25 (12), 2601-2607, 2021 | 34 | 2021 |
Commercial-Scale Visible Light Trifluoromethylation of 2-Chlorothiophenol Using CF3I Gas KC Harper, EX Zhang, ZQ Liu, T Grieme, TB Towne, DJ Mack, J Griffin, ... Organic Process Research & Development 26 (2), 404-412, 2022 | 26 | 2022 |
Phase-transfer catalyzed asymmetric arylacetate alkylation MB Andrus, KC Harper, MA Christiansen, MA Binkley Tetrahedron Letters 50 (31), 4541-4544, 2009 | 23 | 2009 |
Scalable electrochemical decarboxylative olefination driven by alternating polarity AF Garrido‐Castro, Y Hioki, Y Kusumoto, K Hayashi, J Griffin, KC Harper, ... Angewandte Chemie International Edition 62 (42), e202309157, 2023 | 22 | 2023 |
Silanediol anion binding and enantioselective catalysis JW Attard, K Osawa, Y Guan, J Hatt, S Kondo, A Mattson Synthesis 51 (10), 2107-2115, 2019 | 22 | 2019 |
Emerging reaction technologies in pharmaceutical development: Challenges and opportunities in electrochemistry, photochemistry, and biocatalysis B Cohen, D Lehnherr, M Sezen-Edmonds, JH Forstater, MO Frederick, ... Chemical Engineering Research and Design 192, 622-637, 2023 | 18 | 2023 |
Expanding the repertoire for “large small molecules”: prodrug ABBV-167 efficiently converts to venetoclax with reduced food effect in healthy volunteers AH Salem, ZF Tao, OF Bueno, J Chen, S Chen, R Edalji, SW Elmore, ... Molecular Cancer Therapeutics 20 (6), 999-1008, 2021 | 15 | 2021 |
Sequential Reduction of Nitroalkanes Mediated by CS2 and Amidine/Guanidine Bases: A Controllable Nef Reaction M Ju, W Guan, JM Schomaker, KC Harper Organic letters 21 (22), 8893-8898, 2019 | 12 | 2019 |