Total syntheses of ningalin A, lamellarin O, lukianol A, and permethyl storniamide A utilizing heterocyclic azadiene Diels− Alder reactions DL Boger, CW Boyce, MA Labroli, CA Sehon, Q Jin Journal of the American Chemical Society 121 (1), 54-62, 1999 | 527 | 1999 |
CC-1065 and the duocarmycins: synthetic studies DL Boger, CW Boyce, RM Garbaccio, JA Goldberg Chemical reviews 97 (3), 787-828, 1997 | 310 | 1997 |
Total synthesis of ningalin B utilizing a heterocyclic azadiene Diels− Alder reaction and discovery of a new class of potent multidrug resistant (MDR) reversal agents DL Boger, DR Soenen, CW Boyce, MP Hedrick, Q Jin The Journal of organic chemistry 65 (8), 2479-2483, 2000 | 190 | 2000 |
Histamine H3 Receptor as a Drug Discovery Target M Berlin, CW Boyce, M de Lera Ruiz Journal of medicinal chemistry 54 (1), 26-53, 2011 | 169 | 2011 |
Dual plasmepsin-targeting antimalarial agents disrupt multiple stages of the malaria parasite life cycle P Favuzza, M de Lera Ruiz, JK Thompson, T Triglia, A Ngo, RWJ Steel, ... Cell host & microbe 27 (4), 642-658. e12, 2020 | 107 | 2020 |
Synthesis, chemical properties, and preliminary evaluation of substituted CBI analogs of CC-1065 and the duocarmycins incorporating the 7-cyano-1, 2, 9, 9a-tetrahydrocyclopropa … DL Boger, N Han, CM Tarby, CW Boyce, H Cai, Q Jin, PA Kitos The Journal of Organic Chemistry 61 (15), 4894-4912, 1996 | 82 | 1996 |
Synthesis of CC-1065 and duocarmycin analogs via intramolecular aryl radical cyclization of a tethered vinyl chloride DL Boger, CW Boyce, RM Garbaccio, M Searcey Tetrahedron letters 39 (16), 2227-2230, 1998 | 65 | 1998 |
Selective Metal Cation Activation of a DNA Alkylating Agent: Synthesis and Evaluation of Methyl 1,2,9,9a-Tetrahydrocyclopropa[c]pyrido[3,2-e]indol-4-one-7 … DL Boger, CW Boyce The Journal of Organic Chemistry 65 (13), 4088-4100, 2000 | 59 | 2000 |
Benzimidazole derivatives useful as histamine H3 antagonists Q Zeng, RG Aslanian, MY Berlin, CW Boyce, J Cao, JA Kozlowski, ... US Patent 7,105,505, 2006 | 53 | 2006 |
Phenoxypiperidines and analogs thereof useful as histamine H3 antagonists MW Mutahi, RG Aslanian, MY Berlin, CW Boyce, M de Lera Ruiz, ... US Patent 7,638,531, 2009 | 52 | 2009 |
Benzimidazolone histamine H3 antagonists PC Ting, RG Aslanian, MY Berlin, CW Boyce, J Cao, P Mangiaracina, ... US Patent 7,220,735, 2007 | 47 | 2007 |
Functionally selective ALPHA2C adrenoreceptor agonists KD McCormick, CW Boyce, Y Yu US Patent 8,003,624, 2011 | 42 | 2011 |
Recent advances in the development of histamine H3 antagonists M Berlin, CW Boyce Expert Opinion on Therapeutic Patents 17 (6), 675-687, 2007 | 41 | 2007 |
pH Dependence of the rate of DNA alkylation for (+)-duocarmycin SA and (+)-CCBI-TMI DL Boger, CW Boyce, DS Johnson Bioorganic & Medicinal Chemistry Letters 7 (2), 233-238, 1997 | 35 | 1997 |
CBI Prodrug Analogs of CC-1065 and the Duocarmycins DL Boger, CW Boyce, RM Garbaccio, M Searcey, Q Jin Synthesis 1999 (S 01), 1505-1509, 1999 | 31 | 1999 |
Novel compounds that are ERK inhibitors J Lim, EH Kelley, JL Methot, H Zhou, A Petrocchi, UF Mansoor, C Fischer, ... | 29 | 2013 |
Synthesis of trifluoromethylated pyrroles via a one-pot three-component reaction F Rahmani, A Darehkordi Synlett 28 (10), 1224-1226, 2017 | 25 | 2017 |
A new method of in situ activation for a novel class of DNA alkylating agents: tunable metal cation complexation and activation DL Boger, SE Wolkenberg, CW Boyce Journal of the American Chemical Society 122 (26), 6325-6326, 2000 | 24 | 2000 |
Asymmetric synthesis of the CBI alkylation subunit of the CC-1065 and duocarmycin analogs DL Boger, JA McKie, CW Boyce Synlett 1997 (Sup. I), 515-517, 1997 | 24 | 1997 |
Concise synthesis of lamellarin alkaloids by C–H/N–H activation: evaluation of metal catalysts in oxidative alkyne annulation R Mei, SK Zhang, L Ackermann Synlett 28 (14), 1715-1718, 2017 | 22 | 2017 |