Allosteric modulation of G protein-coupled receptors: a pharmacological perspective P Keov, PM Sexton, A Christopoulos Neuropharmacology 60 (1), 24-35, 2011 | 299 | 2011 |
The TRPV4 agonist GSK1016790A regulates the membrane expression of TRPV4 channels S Baratchi, P Keov, WG Darby, A Lai, K Khoshmanesh, P Thurgood, ... Frontiers in pharmacology 10, 6, 2019 | 79 | 2019 |
Molecular mechanisms of bitopic ligand engagement with the M1 muscarinic acetylcholine receptor P Keov, L Lopez, SM Devine, C Valant, JR Lane, PJ Scammells, ... Journal of Biological Chemistry 289 (34), 23817-23837, 2014 | 73 | 2014 |
Molecular determinants of allosteric modulation at the M1 muscarinic acetylcholine receptor A Abdul-Ridha, L Lopez, P Keov, DM Thal, SN Mistry, PM Sexton, ... Journal of Biological Chemistry 289 (9), 6067-6079, 2014 | 73 | 2014 |
Development of a human vasopressin V1a-receptor antagonist from an evolutionary-related insect neuropeptide MG Di Giglio, M Muttenthaler, K Harpsøe, Z Liutkeviciute, P Keov, T Eder, ... Scientific Reports 7 (1), 41002, 2017 | 42 | 2017 |
Reverse engineering of the selective agonist TBPB unveils both orthosteric and allosteric modes of action at the M1 muscarinic acetylcholine receptor P Keov, C Valant, SM Devine, JR Lane, PJ Scammells, PM Sexton, ... Molecular Pharmacology 84 (3), 425-437, 2013 | 40 | 2013 |
Contractility measurements of human uterine smooth muscle to aid drug development S Arrowsmith, P Keov, M Muttenthaler, CW Gruber JoVE (Journal of Visualized Experiments), e56639, 2018 | 37 | 2018 |
AM833 is a novel agonist of calcitonin family G protein–coupled receptors: pharmacological comparison with six selective and nonselective agonists MM Fletcher, P Keov, TT Truong, G Mennen, CA Hick, P Zhao, ... Journal of Pharmacology and Experimental Therapeutics 377 (3), 417-440, 2021 | 33 | 2021 |
Cyclotides isolated from an ipecac root extract antagonize the corticotropin releasing factor type 1 receptor M Fahradpour, P Keov, C Tognola, E Perez-Santamarina, PJ McCormick, ... Frontiers in Pharmacology 8, 616, 2017 | 32 | 2017 |
Discovery of peptide probes to modulate oxytocin-type receptors of insects P Keov, Z Liutkevičiūtė, R Hellinger, RJ Clark, CW Gruber Scientific reports 8 (1), 10020, 2018 | 17 | 2018 |
Nature-inspired dimerization as a strategy to modulate neuropeptide pharmacology exemplified with vasopressin and oxytocin Z Dekan, T Kremsmayr, P Keov, M Godin, N Teakle, L Dürrauer, H Xiang, ... Chemical Science 12 (11), 4057-4062, 2021 | 16 | 2021 |
Orphan receptor GPR37L1 remains unliganded T Ngo, BP Wilkins, SS So, P Keov, KK Chahal, AM Finch, JLJ Coleman, ... Nature chemical biology 17 (4), 383-386, 2021 | 10 | 2021 |
Tackling the complexities of orphan GPCR ligand discovery with rationally assisted approaches SS So, T Ngo, P Keov, NJ Smith, I Kufareva GPCRs, 295-334, 2020 | 9 | 2020 |
I8-arachnotocin–an arthropod-derived G protein-biased ligand of the human vasopressin V2 receptor L Duerrauer, E Muratspahić, J Gattringer, P Keov, HC Mendel, ... Scientific Reports 9 (1), 19295, 2019 | 8 | 2019 |
Discovery and development of macrocyclic peptide modulators of the cannabinoid 2 receptor N Tomašević, FS Emser, E Muratspahić, J Gattringer, S Hasinger, ... Journal of Biological Chemistry 300 (6), 107330, 2024 | | 2024 |
Development of a Novel Assay for Direct Assessment of Selective Amylin Receptor Activation Reveals Novel Differences in Behavior of Selective and Nonselective Peptide Agonists P Keov, G Christopoulos, CA Hick, T Glendorf, B Ballarín-González, ... Molecular Pharmacology 105 (5), 359-373, 2024 | | 2024 |
Role of G protein‐coupled receptor kinases (GRKs) in β2‐adrenoceptor‐mediated glucose uptake S Ham, S Mukaida, M Sato, P Keov, T Bengtsson, S Furness, ND Holliday, ... Pharmacology Research & Perspectives 12 (1), e1176, 2024 | | 2024 |
Orphan G protein-coupled receptor, GPR37L1: pharmacological toolbox empty once again T Ngo, BP Wilkins, SS So, P Keov, KK Chahal, AM Finch, JLJ Coleman, ... bioRxiv, 2020.09. 11.290486, 2020 | | 2020 |
Pharmacological Characterisation of the Cyclotide Kalata B7 At Insect Orthologues of the Oxytocin/vasopressin Receptors P Keov, Z Liutkeviciute, R Clark, C Gruber Journal Of Peptide Science 22, S86-S86, 2016 | | 2016 |
Structural and mechanistic studies of novel selective agonists of the M1 muscarinic acetylcholine receptor P Keov Monash University, 2014 | | 2014 |