The mammalian CTLH complex is an E3 ubiquitin ligase that targets its subunit muskelin for degradation MER Maitland, G Onea, CA Chiasson, XU Wang, J Ma, SE Moor, ... Scientific reports 9 (1), 9864, 2019 | 53 | 2019 |
Cell signalling pathway regulation by RanBPM: molecular insights and disease implications LM Salemi, MER Maitland, CJ McTavish, C Schild-Poulter Open biology 7 (6), 170081, 2017 | 40 | 2017 |
Proteomic analysis of ubiquitination substrates reveals a CTLH E3 ligase complex‐dependent regulation of glycolysis MER Maitland, M Kuljanin, X Wang, GA Lajoie, C Schild‐Poulter The FASEB Journal 35 (9), 2021 | 25 | 2021 |
Regulation of c-Raf Stability through the CTLH Complex CJ McTavish, W Bérubé-Janzen, X Wang, MER Maitland, LM Salemi, ... International journal of molecular sciences 20 (4), 934, 2019 | 20 | 2019 |
Structural and functional insights into GID/CTLH E3 ligase complexes MER Maitland, GA Lajoie, GS Shaw, C Schild-Poulter International Journal of Molecular Sciences 23 (11), 5863, 2022 | 19 | 2022 |
Inhibition of HDAC6 activity through interaction with RanBPM and its associated CTLH complex LM Salemi, MER Maitland, ER Yefet, C Schild-Poulter BMC cancer 17, 1-16, 2017 | 17 | 2017 |
Stress-inducible phosphoprotein 1 (HOP/STI1/STIP1) regulates the accumulation and toxicity of α-synuclein in vivo RE Lackie, AS de Miranda, MP Lim, V Novikov, N Madrer, ... Acta Neuropathologica 144 (5), 881-910, 2022 | 14 | 2022 |
Distinct nuclear and cytoplasmic assemblies and interactomes of the mammalian CTLH E3 ligase complex G Onea, MER Maitland, X Wang, GA Lajoie, C Schild-Poulter Journal of Cell Science 135 (14), jcs259638, 2022 | 11 | 2022 |
Specific quinone reductase 2 inhibitors reduce metabolic burden and reverse Alzheimer’s disease phenotype in mice NL Gould, GR Scherer, S Carvalho, K Shurrush, H Kayyal, E Edry, ... The Journal of Clinical Investigation 133 (19), 2023 | 7 | 2023 |
A chemical probe to modulate human GID4 Pro/N-degron interactions DDG Owens, MER Maitland, A Khalili Yazdi, X Song, V Reber, ... Nature Chemical Biology, 1-12, 2024 | 6 | 2024 |
Recruitment of FBXO22 for targeted degradation of NSD2 DY Nie, JR Tabor, J Li, M Kutera, J St-Germain, RP Hanley, E Wolf, ... Nature Chemical Biology, 1-11, 2024 | 4 | 2024 |
Interplay between β-propeller subunits WDR26 and muskelin regulates the CTLH E3 ligase supramolecular complex MER Maitland, G Onea, DDG Owens, BC Gonga-Cavé, X Wang, ... bioRxiv, 2024.03. 08.584134, 2024 | 1 | 2024 |
Therapeutic Discovery for Chromatin Complexes: Where Do We Stand? DDG Owens, MER Maitland, CH Arrowsmith, D Barsyte-Lovejoy Annual Review of Cancer Biology 8, 2024 | | 2024 |
Noncanonical functions of Ku may underlie essentiality in human cells RD Kelly, G Parmar, L Bayat, MER Maitland, GA Lajoie, DR Edgell, ... Scientific Reports 13 (1), 12162, 2023 | | 2023 |
Identifying Cytoplasmic and Nuclear C‐Terminal to LisH (CTLH) Complex Interactors Using High‐Throughput Proteomics G Onea, M Maitland, G Lajoie, C Schild‐Poulter The FASEB Journal 35, 2021 | | 2021 |
Uncovering the ubiquitin ligase activity and substrates of the human C-terminal to LisH (CTLH) complex MER Maitland | | 2021 |
The role of thymine DNA glycosylase (TDG) and DNA demethylation in TGF beta signaling MER Maitland The University of Western Ontario (Canada), 2015 | | 2015 |