YAP aggravates inflammatory bowel disease by regulating M1/M2 macrophage polarization and gut microbial homeostasis X Zhou, W Li, S Wang, P Zhang, Q Wang, J Xiao, C Zhang, X Zheng, X Xu, ... Cell reports 27 (4), 1176-1189. e5, 2019 | 257 | 2019 |
STK4 regulates TLR pathways and protects against chronic inflammation–related hepatocellular carcinoma W Li, J Xiao, X Zhou, M Xu, C Hu, X Xu, Y Lu, C Liu, S Xue, L Nie, ... The Journal of clinical investigation 125 (11), 4239-4254, 2015 | 122 | 2015 |
Targeting 7-dehydrocholesterol reductase integrates cholesterol metabolism and IRF3 activation to eliminate infection J Xiao, W Li, X Zheng, L Qi, H Wang, C Zhang, X Wan, Y Zheng, R Zhong, ... Immunity 52 (1), 109-122. e6, 2020 | 111 | 2020 |
Dual-targeting CAR-T cells with optimal co-stimulation and metabolic fitness enhance antitumor activity and prevent escape in solid tumors K Hirabayashi, H Du, Y Xu, P Shou, X Zhou, G Fucá, E Landoni, C Sun, ... Nature cancer 2 (9), 904-918, 2021 | 85 | 2021 |
Polyphyllin I ameliorates collagen-induced arthritis by suppressing the inflammation response in macrophages through the NF-κB pathway Q Wang, X Zhou, Y Zhao, J Xiao, Y Lu, Q Shi, Y Wang, H Wang, Q Liang Frontiers in immunology 9, 2091, 2018 | 75 | 2018 |
M-CSF, IL-6, and TGF-β promote generation of a new subset of tissue repair macrophage for traumatic brain injury recovery Z Li, J Xiao, X Xu, W Li, R Zhong, L Qi, J Chen, G Cui, S Wang, Y Zheng, ... Science advances 7 (11), eabb6260, 2021 | 58 | 2021 |
The natural compound notopterol binds and targets JAK2/3 to ameliorate inflammation and arthritis Q Wang, X Zhou, L Yang, Y Zhao, Z Chew, J Xiao, C Liu, X Zheng, ... Cell reports 32 (11), 2020 | 54 | 2020 |
TET3 inhibits type I IFN production independent of DNA demethylation S Xue, C Liu, X Sun, W Li, C Zhang, X Zhou, Y Lu, J Xiao, C Li, X Xu, ... Cell reports 16 (4), 1096-1105, 2016 | 48 | 2016 |
Gentiopicroside (GENT) protects against sepsis induced by lipopolysaccharide (LPS) through the NF-κB signaling pathway Q Wang, X Zhou, L Yang, M Luo, L Han, Y Lu, Q Shi, Y Wang, Q Liang Annals of Translational Medicine 7 (23), 2019 | 32 | 2019 |
STING suppresses mitochondrial VDAC2 to govern RCC growth independent of innate immunity Z Zhu, X Zhou, H Du, EW Cloer, J Zhang, L Mei, Y Wang, X Tan, ... Advanced Science 10 (3), 2203718, 2023 | 19 | 2023 |
Fully human antibody VH domains to generate mono and bispecific CAR to target solid tumors G Wang, X Zhou, G Fucà, E Dukhovlinova, P Shou, H Li, C Johnston, ... Journal for Immunotherapy of Cancer 9 (4), 2021 | 15 | 2021 |
The roles and mechanisms of MST1/2 in the innate immune response. X Zhou, WY Li, HY Wang Yi Chuan= Hereditas 39 (7), 642-649, 2017 | 6 | 2017 |
4-1BB-encoding CAR causes cell death via sequestration of the ubiquitin-modifying enzyme A20 Z Dou, TR Bonacci, P Shou, E Landoni, MG Woodcock, C Sun, B Savoldo, ... Cellular & Molecular Immunology, 1-13, 2024 | | 2024 |