| Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to … D Scheuner, C Eckman, M Jensen, X Song, M Citron, N Suzuki, TD Bird, ... Nature medicine 2 (8), 864-870, 1996 | 3651 | 1996 |
| Stress granules and processing bodies are dynamically linked sites of mRNP remodeling N Kedersha, G Stoecklin, M Ayodele, P Yacono, J Lykke-Andersen, ... The Journal of cell biology 169 (6), 871-884, 2005 | 1767 | 2005 |
| A selective inhibitor of eIF2α dephosphorylation protects cells from ER stress M Boyce, KF Bryant, C Jousse, K Long, HP Harding, D Scheuner, ... Science 307 (5711), 935-939, 2005 | 1687 | 2005 |
| Translational control is required for the unfolded protein response and in vivo glucose homeostasis D Scheuner, B Song, E McEwen, C Liu, R Laybutt, P Gillespie, ... Molecular cell 7 (6), 1165-1176, 2001 | 1663 | 2001 |
| ER stress‐regulated translation increases tolerance to extreme hypoxia and promotes tumor growth M Bi, C Naczki, M Koritzinsky, D Fels, J Blais, N Hu, H Harding, I Novoa, ... The EMBO journal 24 (19), 3470-3481, 2005 | 931 | 2005 |
| Regulation of starvation-and virus-induced autophagy by the eIF2α kinase signaling pathway Z Talloczy, W Jiang, HW Virgin IV, DA Leib, D Scheuner, RJ Kaufman, ... Proceedings of the National Academy of Sciences 99 (1), 190-195, 2002 | 916 | 2002 |
| Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes B Song, D Scheuner, D Ron, S Pennathur, RJ Kaufman The Journal of clinical investigation 118 (10), 3378-3389, 2008 | 818 | 2008 |
| Translational repression mediates activation of nuclear factor kappa B by phosphorylated translation initiation factor 2 J Deng, PD Lu, Y Zhang, D Scheuner, RJ Kaufman, N Sonenberg, ... Molecular and cellular biology 24 (23), 10161-10168, 2004 | 798 | 2004 |
| The unfolded protein response in nutrient sensing and differentiation RJ Kaufman, D Scheuner, M Schröder, X Shen, K Lee, CY Liu, SM Arnold Nature reviews Molecular cell biology 3 (6), 411-421, 2002 | 798 | 2002 |
| The unfolded protein response: a pathway that links insulin demand with β-cell failure and diabetes D Scheuner, RJ Kaufman Endocrine reviews 29 (3), 317-333, 2008 | 658 | 2008 |
| Phosphorylation of the α subunit of eukaryotic initiation factor 2 is required for activation of NF-κB in response to diverse cellular stresses HY Jiang, SA Wek, BC McGrath, D Scheuner, RJ Kaufman, DR Cavener, ... Molecular and cellular biology, 2003 | 537 | 2003 |
| Heme-regulated inhibitor kinase-mediated phosphorylation of eukaryotic translation initiation factor 2 inhibits translation, induces stress granule formation, and mediates … E McEwen, N Kedersha, B Song, D Scheuner, N Gilks, A Han, JJ Chen, ... Journal of Biological Chemistry 280 (17), 16925-16933, 2005 | 516 | 2005 |
| Control of mRNA translation preserves endoplasmic reticulum function in beta cells and maintains glucose homeostasis D Scheuner, DV Mierde, B Song, D Flamez, JWM Creemers, K Tsukamoto, ... Nature medicine 11 (7), 757-764, 2005 | 472 | 2005 |
| Cytoprotection by pre‐emptive conditional phosphorylation of translation initiation factor 2 PD Lu, C Jousse, SJ Marciniak, Y Zhang, I Novoa, D Scheuner, ... The EMBO journal 23 (1), 169-179, 2004 | 445 | 2004 |
| The unfolded protein response sensor IRE1α is required at 2 distinct steps in B cell lymphopoiesis K Zhang, HN Wong, B Song, CN Miller, D Scheuner, RJ Kaufman The Journal of clinical investigation 115 (2), 268-281, 2005 | 430 | 2005 |
| Translation attenuation through eIF2α phosphorylation prevents oxidative stress and maintains the differentiated state in β cells SH Back, D Scheuner, J Han, B Song, M Ribick, J Wang, RD Gildersleeve, ... Cell metabolism 10 (1), 13-26, 2009 | 416 | 2009 |
| Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development HP Harding, Y Zhang, D Scheuner, JJ Chen, RJ Kaufman, D Ron Proceedings of the national academy of sciences 106 (6), 1832-1837, 2009 | 301 | 2009 |
| Protein kinase R contributes to immunity against specific viruses by regulating interferon mRNA integrity O Schulz, A Pichlmair, J Rehwinkel, NC Rogers, D Scheuner, H Kato, ... Cell host & microbe 7 (5), 354-361, 2010 | 205 | 2010 |
| Double-stranded RNA-dependent protein kinase phosphorylation of the α-subunit of eukaryotic translation initiation factor 2 mediates apoptosis D Scheuner, R Patel, F Wang, K Lee, K Kumar, J Wu, A Nilsson, M Karin, ... Journal of Biological Chemistry 281 (30), 21458-21468, 2006 | 171 | 2006 |
| The IRE1α/XBP1s pathway is essential for the glucose response and protection of β cells JR Hassler, DL Scheuner, S Wang, J Han, VK Kodali, P Li, J Nguyen, ... PLoS biology 13 (10), e1002277, 2015 | 165 | 2015 |
