Interactions of SARS-CoV-2 with the blood–brain barrier MA Erickson, EM Rhea, RC Knopp, WA Banks International Journal of Molecular Sciences 22 (5), 2681, 2021 | 146 | 2021 |
Design, synthesis, and biological evaluation of tetrahydroisoquinoline-based histone deacetylase 8 selective inhibitors TY Taha, SM Aboukhatwa, RC Knopp, N Ikegaki, H Abdelkarim, ... ACS Medicinal Chemistry Letters 8 (8), 824-829, 2017 | 40 | 2017 |
Interaction of oxidative stress and neurotrauma in ALDH2−/− mice causes significant and persistent behavioral and pro-inflammatory effects in a tractable model of mild … RC Knopp, SH Lee, M Hollas, E Nepomuceno, D Gonzalez, K Tam, ... Redox biology 32, 101486, 2020 | 23 | 2020 |
Physical associations of microglia and the vascular blood-brain barrier and their importance in development, health, and disease RC Knopp, WA Banks, MA Erickson Current Opinion in Neurobiology 77, 102648, 2022 | 13 | 2022 |
Amyloid beta pathology exacerbates weight loss and brain cytokine responses following low-dose lipopolysaccharide in aged female Tg2576 mice RC Knopp, KK Baumann, ML Wilson, WA Banks, MA Erickson International Journal of Molecular Sciences 23 (4), 2377, 2022 | 12 | 2022 |
Cellular senescence and the blood–brain barrier: Implications for aging and age-related diseases RC Knopp, MA Erickson, EM Rhea, MJ Reed, WA Banks Experimental Biology and Medicine 248 (5), 399-411, 2023 | 11 | 2023 |
Variation of the aryl substituent on the piperazine ring within the 4-(piperazin-1-yl)-2, 6-di (pyrrolidin-1-yl) pyrimidine scaffold unveils potent, non-competitive inhibitors … CR Kent, M Bryja, HA Gustafson, MY Kawarski, G Lenti, EN Pierce, ... Bioorganic & Medicinal Chemistry Letters 26 (22), 5476-5480, 2016 | 11 | 2016 |
Extending the Calpain–Cathepsin Hypothesis to the Neurovasculature: Protection of Brain Endothelial Cells and Mice from Neurotrauma RC Knopp, A Jastaniah, O Dubrovskyi, I Gaisina, L Tai, GRJ Thatcher ACS Pharmacology & Translational Science 4 (1), 372-385, 2021 | 9 | 2021 |
Synthesis of α‐ketoamide‐based stereoselective calpain‐1 inhibitors as neuroprotective agents A Jastaniah, IN Gaisina, RC Knopp, GRJ Thatcher ChemMedChem 15 (23), 2280-2285, 2020 | 6 | 2020 |
Correction to design, synthesis, and biological evaluation of tetrahydroisoquinoline-based histone deacetylase 8 selective inhibitors TY Taha, SM Aboukhatwa, RC Knopp, N Ikegaki, H Abdelkarim, ... ACS Medicinal Chemistry Letters 10 (9), 1358-1358, 2019 | 4 | 2019 |
P1‐083: NOVEL NAMPT ACTIVATORS ATTENUATE NEUROTOXICITY AND NEUROINFLAMMATION ASSOCIATED WITH NEURODEGENERATION J Gordon-Blake, B Karumudi, K Ratia, RC Knopp, K Dye, M Ben Aissa, ... Alzheimer's & Dementia 15, P266-P267, 2019 | 4 | 2019 |
Cysteine Proteases as Therapeutic Targets for Neurodegenerative Diseases R Knopp University of Illinois at Chicago, 2020 | | 2020 |
P3‐062: CALPAIN‐1 IN NEURODEGENERATION: EVALUATING THERAPEUTIC EFFICACY OF INHIBITION STRATEGIES RC Knopp, A Jastinah, O Dubrovskyi, SH Lee, L Tai, GR Thatcher Alzheimer's & Dementia 15, P949-P949, 2019 | | 2019 |
Design and synthesis of peptidomimetics with attenuated reactivity for the treatment of neurodegenerative diseases A Jastaniah, R Knopp, I Gaisina, M Siklos, G Thatcher ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 257, 2019 | | 2019 |
P1‐220: SELECTIVE CALPAIN‐1 VERSUS CALPAIN‐1/CATHEPSIN‐B DUAL INHIBITION AS A THERAPEUTIC APPROACH TO AD RC Knopp, M Ben Aissa, A Jastinah, SH Lee, R Izar Alzheimer's & Dementia 14 (7S_Part_6), P362-P363, 2018 | | 2018 |