General fractional derivatives: theory, methods and applications XJ Yang Chapman and Hall/CRC, 2019 | 433 | 2019 |
Structure−Activity Relationships of the p38α MAP Kinase Inhibitor 1-(5-tert-Butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-[4-(2-morpholin-4-yl-ethoxy)naph- thalen-1-yl]urea … J Regan, A Capolino, PF Cirillo, T Gilmore, AG Graham, E Hickey, ... Journal of medicinal chemistry 46 (22), 4676-4686, 2003 | 167 | 2003 |
Discovery and characterization of a substrate selective p38α inhibitor W Davidson, L Frego, GW Peet, RR Kroe, ME Labadia, SM Lukas, ... Biochemistry 43 (37), 11658-11671, 2004 | 151 | 2004 |
Comparison of biosensor platforms in the evaluation of high affinity antibody-antigen binding kinetics D Yang, A Singh, H Wu, R Kroe-Barrett Analytical biochemistry 508, 78-96, 2016 | 136 | 2016 |
Selective targeting of the IL23 pathway: generation and characterization of a novel high-affinity humanized anti-IL23A antibody S Singh, RR Kroe-Barrett, KA Canada, X Zhu, E Sepulveda, H Wu, Y He, ... MAbs 7 (4), 778-791, 2015 | 107 | 2015 |
Competing aggregation pathways for monoclonal antibodies H Wu, R Kroe-Barrett, S Singh, AS Robinson, CJ Roberts FEBS letters 588 (6), 936-941, 2014 | 97 | 2014 |
Dabigatran anticoagulant activity is neutralized by an antibody selective to dabigatran in in vitro and in vivo models J Van Ryn, T Litzenburger, A Waterman, K Canada, N Hauel, C Sarko, ... Journal of the American College of Cardiology 57 (14S), E1130-E1130, 2011 | 95 | 2011 |
NUTS and BOLTS: applications of fluorescence-detected sedimentation RR Kroe, TM Laue Analytical biochemistry 390 (1), 1-13, 2009 | 93 | 2009 |
Generation and functional characterization of anti-human and anti-mouse IL-36R antagonist monoclonal antibodies R Ganesan, EL Raymond, D Mennerich, JR Woska Jr, G Caviness, ... MAbs 9 (7), 1143-1154, 2017 | 85 | 2017 |
IgG charge: practical and biological implications D Yang, R Kroe-Barrett, S Singh, T Laue Antibodies 8 (1), 24, 2019 | 80 | 2019 |
IgG cooperativity–Is there allostery? Implications for antibody functions and therapeutic antibody development D Yang, R Kroe-Barrett, S Singh, CJ Roberts, TM Laue MAbs 9 (8), 1231-1252, 2017 | 73 | 2017 |
Catalysis and Function of the p38α⊙ MK2a Signaling Complex SM Lukas, RR Kroe, J Wildeson, GW Peet, L Frego, W Davidson, ... Biochemistry 43 (31), 9950-9960, 2004 | 68 | 2004 |
Thermal denaturation: A method to rank slow binding, high-affinity P38α MAP kinase inhibitors RR Kroe, J Regan, A Proto, GW Peet, T Roy, LD Landro, NG Fuschetto, ... Journal of medicinal chemistry 46 (22), 4669-4675, 2003 | 68 | 2003 |
Design and characterization of Zweimab and Doppelmab, high affinity dual antagonistic anti-TSLP/IL13 bispecific antibodies S Venkataramani, S Low, B Weigle, D Dutcher, K Jerath, M Menzenski, ... Biochemical and biophysical research communications 504 (1), 19-24, 2018 | 44 | 2018 |
Biophysical techniques for characterizing the higher order structure and interactions of monoclonal antibodies Y Gokarn, S Agarwal, K Arthur, A Bepperling, ES Day, D Filoti, DG Greene, ... State-of-the-Art and Emerging Technologies for Therapeutic Monoclonal …, 2015 | 42 | 2015 |
Discovery and design of benzimidazolone based inhibitors of p38 MAP kinase A Hammach, A Barbosa, FC Gaenzler, T Fadra, D Goldberg, MH Hao, ... Bioorganic & medicinal chemistry letters 16 (24), 6316-6320, 2006 | 42 | 2006 |
Canada KA, Zhu X, Sepulveda E, Wu H, et al S Singh, RR Kroe-Barrett Selective targeting of the IL23 pathway: generation and characterization of …, 2015 | 39 | 2015 |
VHH antibody targeting the chemokine receptor CX3CR1 inhibits progression of atherosclerosis S Low, H Wu, K Jerath, A Tibolla, B Fogal, R Conrad, D Webb, ... MAbs 12 (1), 1709322, 2020 | 36 | 2020 |
Determination of high-affinity antibody-antigen binding kinetics using four biosensor platforms D Yang, A Singh, H Wu, R Kroe-Barrett JoVE (Journal of Visualized Experiments), e55659, 2017 | 30 | 2017 |
Maximizing in vivo target clearance by design of pH-dependent target binding antibodies with altered affinity to FcRn D Yang, C Giragossian, S Castellano, M Lasaro, H Xiao, H Saraf, ... MAbs 9 (7), 1105-1117, 2017 | 28 | 2017 |