The role of hypoxia-inducible factor post-translational modifications in regulating its localisation, stability, and activity A Albanese, LA Daly, D Mennerich, T Kietzmann, V Sée International journal of molecular sciences 22 (1), 268, 2020 | 98 | 2020 |
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential B Meyer, J Chiaravalli, S Gellenoncourt, P Brownridge, DP Bryne, LA Daly, ... Nature Communications 12 (1), 5553, 2021 | 92 | 2021 |
Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity DP Byrne, S Shrestha, M Galler, M Cao, LA Daly, AE Campbell, CE Eyers, ... Science signaling 13 (639), eaax2713, 2020 | 77 | 2020 |
Oxygen-dependent changes in binding partners and post-translational modifications regulate the abundance and activity of HIF-1α/2α LA Daly, PJ Brownridge, M Batie, S Rocha, V Sée, CE Eyers Science signaling 14 (692), eabf6685, 2021 | 27 | 2021 |
Mechanism of glycogen synthase inactivation and interaction with glycogenin L Marr, D Biswas, LA Daly, C Browning, SCM Vial, DP Maskell, C Hudson, ... Nature communications 13 (1), 3372, 2022 | 26 | 2022 |
Mislocalization of protein kinase A drives pathology in Cushing’s syndrome MH Omar, DP Byrne, KN Jones, TM Lakey, KB Collins, KS Lee, LA Daly, ... Cell reports 40 (2), 2022 | 18 | 2022 |
Characterisation of protease activity during SARS-CoV-2 infection identifies novel viral cleavage sites and cellular targets with therapeutic potential B Meyer, J Chiaravalli, S Gellenoncourt, P Brownridge, DP Bryne, LA Daly, ... BioRxiv, 2020.09. 16.297945, 2020 | 15 | 2020 |
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential. Nat Commun 12: 5553 B Meyer, J Chiaravalli, S Gellenoncourt, P Brownridge, DP Bryne, LA Daly, ... | 9 | 2021 |
Custom workflow for the confident identification of sulfotyrosine-containing peptides and their discrimination from phosphopeptides LA Daly, DP Byrne, S Perkins, PJ Brownridge, E McDonnell, AR Jones, ... Journal of Proteome Research 22 (12), 3754-3772, 2023 | 4 | 2023 |
Oxygen-dependent changes in HIF binding partners and post-translational modifications regulate stability and transcriptional activity L Daly, PJ Brownridge, V Sée, CE Eyers bioRxiv, 2020.11. 12.379768, 2020 | 4 | 2020 |
Mechanistic and evolutionary insights into isoform-specific ‘supercharging’in DCLK family kinases A Venkat, G Watterson, DP Byrne, B O'Boyle, S Shrestha, N Gravel, ... Elife 12, RP87958, 2023 | 3 | 2023 |
Evolutionary and cellular analysis of the ‘dark’pseudokinase PSKH2 DP Byrne, S Shrestha, LA Daly, V Marensi, K Ramakrishnan, CE Eyers, ... Biochemical Journal 480 (2), 141-160, 2023 | 3 | 2023 |
Considerations for defining+ 80 Da mass shifts in mass spectrometry-based proteomics: phosphorylation and beyond LA Daly, CJ Clarke, A Po, SO Oswald, CE Eyers Chemical Communications 59 (77), 11484-11499, 2023 | 3 | 2023 |
Redox regulation of brain selective kinases BRSK1/2: Implications for dynamic control of the eukaryotic AMPK family through Cys-based mechanisms GN Bendzunas, DP Byrne, S Shrestha, LA Daly, SO Oswald, S Katiyar, ... bioRxiv, 2023 | 1 | 2023 |
A bespoke analytical workflow for the confident identification of sulfopeptides and their discrimination from phosphopeptides LA Daly, DP Byrne, S Perkins, PJ Brownridge, E McDonnell, AR Jones, ... bioRxiv, 2023.07. 15.549150, 2023 | 1 | 2023 |
Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs MH Omar, DP Byrne, S Shrestha, TM Lakey, KS Lee, SM Lauer, ... Science Advances 10 (8), eadl1258, 2024 | | 2024 |
Displacement of PKA catalytic subunit from AKAP signaling islands drives pathology in Cushing’s syndrome MH Omar, DP Byrne, KN Jones, TM Lakey, KB Collins, KS Lee, LA Daly, ... bioRxiv, 2021.10. 18.464848, 2021 | | 2021 |
Amphipathic Fluorescent Dyes for Sensitive and Long-Term Monitoring of Plasma Membranes L Daly Science Signaling, 2020 | | 2020 |
Identification and Characterisation of the Post-translational Modifications that Regulate the Hypoxia Inducible Factors, HIF-1α and HIF-2α L Daly PQDT-Global, 2020 | | 2020 |