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Leonard Daly
Leonard Daly
Dr
在 liverpool.ac.uk 的电子邮件经过验证
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引用次数
引用次数
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The role of hypoxia-inducible factor post-translational modifications in regulating its localisation, stability, and activity
A Albanese, LA Daly, D Mennerich, T Kietzmann, V Sée
International journal of molecular sciences 22 (1), 268, 2020
982020
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential
B Meyer, J Chiaravalli, S Gellenoncourt, P Brownridge, DP Bryne, LA Daly, ...
Nature Communications 12 (1), 5553, 2021
922021
Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity
DP Byrne, S Shrestha, M Galler, M Cao, LA Daly, AE Campbell, CE Eyers, ...
Science signaling 13 (639), eaax2713, 2020
772020
Oxygen-dependent changes in binding partners and post-translational modifications regulate the abundance and activity of HIF-1α/2α
LA Daly, PJ Brownridge, M Batie, S Rocha, V Sée, CE Eyers
Science signaling 14 (692), eabf6685, 2021
272021
Mechanism of glycogen synthase inactivation and interaction with glycogenin
L Marr, D Biswas, LA Daly, C Browning, SCM Vial, DP Maskell, C Hudson, ...
Nature communications 13 (1), 3372, 2022
262022
Mislocalization of protein kinase A drives pathology in Cushing’s syndrome
MH Omar, DP Byrne, KN Jones, TM Lakey, KB Collins, KS Lee, LA Daly, ...
Cell reports 40 (2), 2022
182022
Characterisation of protease activity during SARS-CoV-2 infection identifies novel viral cleavage sites and cellular targets with therapeutic potential
B Meyer, J Chiaravalli, S Gellenoncourt, P Brownridge, DP Bryne, LA Daly, ...
BioRxiv, 2020.09. 16.297945, 2020
152020
Characterising proteolysis during SARS-CoV-2 infection identifies viral cleavage sites and cellular targets with therapeutic potential. Nat Commun 12: 5553
B Meyer, J Chiaravalli, S Gellenoncourt, P Brownridge, DP Bryne, LA Daly, ...
92021
Custom workflow for the confident identification of sulfotyrosine-containing peptides and their discrimination from phosphopeptides
LA Daly, DP Byrne, S Perkins, PJ Brownridge, E McDonnell, AR Jones, ...
Journal of Proteome Research 22 (12), 3754-3772, 2023
42023
Oxygen-dependent changes in HIF binding partners and post-translational modifications regulate stability and transcriptional activity
L Daly, PJ Brownridge, V Sée, CE Eyers
bioRxiv, 2020.11. 12.379768, 2020
42020
Mechanistic and evolutionary insights into isoform-specific ‘supercharging’in DCLK family kinases
A Venkat, G Watterson, DP Byrne, B O'Boyle, S Shrestha, N Gravel, ...
Elife 12, RP87958, 2023
32023
Evolutionary and cellular analysis of the ‘dark’pseudokinase PSKH2
DP Byrne, S Shrestha, LA Daly, V Marensi, K Ramakrishnan, CE Eyers, ...
Biochemical Journal 480 (2), 141-160, 2023
32023
Considerations for defining+ 80 Da mass shifts in mass spectrometry-based proteomics: phosphorylation and beyond
LA Daly, CJ Clarke, A Po, SO Oswald, CE Eyers
Chemical Communications 59 (77), 11484-11499, 2023
32023
Redox regulation of brain selective kinases BRSK1/2: Implications for dynamic control of the eukaryotic AMPK family through Cys-based mechanisms
GN Bendzunas, DP Byrne, S Shrestha, LA Daly, SO Oswald, S Katiyar, ...
bioRxiv, 2023
12023
A bespoke analytical workflow for the confident identification of sulfopeptides and their discrimination from phosphopeptides
LA Daly, DP Byrne, S Perkins, PJ Brownridge, E McDonnell, AR Jones, ...
bioRxiv, 2023.07. 15.549150, 2023
12023
Discovery of a Cushing’s syndrome protein kinase A mutant that biases signaling through type I AKAPs
MH Omar, DP Byrne, S Shrestha, TM Lakey, KS Lee, SM Lauer, ...
Science Advances 10 (8), eadl1258, 2024
2024
Displacement of PKA catalytic subunit from AKAP signaling islands drives pathology in Cushing’s syndrome
MH Omar, DP Byrne, KN Jones, TM Lakey, KB Collins, KS Lee, LA Daly, ...
bioRxiv, 2021.10. 18.464848, 2021
2021
Amphipathic Fluorescent Dyes for Sensitive and Long-Term Monitoring of Plasma Membranes
L Daly
Science Signaling, 2020
2020
Identification and Characterisation of the Post-translational Modifications that Regulate the Hypoxia Inducible Factors, HIF-1α and HIF-2α
L Daly
PQDT-Global, 2020
2020
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