Elevated expression of MiR-17 in microglia of Alzheimer’s disease patients abrogates autophagy-mediated amyloid-β degradation S Estfanous, KP Daily, M Eltobgy, NP Deems, MNK Anne, K Krause, ... Frontiers in immunology 12, 705581, 2021 | 44 | 2021 |
The molecular basis of the interactions between synthetic retinoic acid analogues and the retinoic acid receptors H Haffez, DR Chisholm, R Valentine, E Pohl, C Redfern, A Whiting MedChemComm 8 (3), 578-592, 2017 | 35 | 2017 |
Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo SSAOA Shady Estfanous, Kathrin Krause, Midhun N. K. Anne, Mostafa Eltobgy ... Scientific Reports 11, 2021 | 32 | 2021 |
Growth inhibition and apoptotic effect of pine extract and abietic acid on MCF-7 breast cancer cells via alteration of multiple gene expressions using in vitro approach H Haffez, S Osman, HY Ebrahim, ZA Hassan Molecules 27 (1), 293, 2022 | 18 | 2022 |
Probing biological activity through structural modelling of ligand-receptor interactions of 2, 4-disubstituted thiazole retinoids H Haffez, DR Chisholm, NJ Tatum, R Valentine, C Redfern, E Pohl, ... Bioorganic & medicinal chemistry 26 (8), 1560-1572, 2018 | 17 | 2018 |
Raptinal silver nanoparticles: new therapeutic advances in hepatocellular carcinoma mouse model T Heba, E Nourhan, H Hesham, H Zeineb Naunyn-Schmiedeberg's Archives of Pharmacology, 2020 | 16 | 2020 |
Novel thienopyrimidine analogues as potential metabotropic glutamate receptors inhibitors and anticancer activity: Synthesis, In-vitro, In-silico, and SAR approaches MA Khedr, KM Abu-Zied, WA Zaghary, AS Aly, DN Shouman, H Haffez Bioorganic Chemistry 109, 104729, 2021 | 14 | 2021 |
Revealing the Potential Application of EC-Synthetic Retinoid Analogues in Anticancer Therapy MREHH Mohamed R. Abdelaal, Sameh H. Soror Molecules 26 (2), 506, 2021 | 13 | 2021 |
Neurogenesis in response to synthetic retinoids at different temporal scales H Haffez, T Khatib, P McCaffery, S Przyborski, C Redfern, A Whiting Molecular Neurobiology 55, 1942-1950, 2018 | 13 | 2018 |
Synthesis, biological evaluation and molecular docking studies of novel thiopyrimidine analogue as apoptotic agent with potential anticancer activity H Haffez, H Taha, MA Rabie, SM Awad, YM Zohny Bioorganic Chemistry 104, 104249, 2020 | 12 | 2020 |
The potential roles of retinoids in combating drug resistance in cancer: implications of ATP-binding cassette (ABC) transporters MRAH Haffez Open biology 12 (6), 2022 | 9 | 2022 |
Biological screening and radiolabeling of raptinal as a potential anticancer novel drug in hepatocellular carcinoma model H Haffez, H Taha, NS Farrag, AM Amin, ZA Hassan European Journal of Pharmaceutical Sciences 158, 105653, 2021 | 6 | 2021 |
SYNTHESIS, ANTICANCER ACTIVITY AND MOLECULAR DOCKING STUDY OF SOME NOVEL 2-THIOURACIL SULFONAMIDE DERIVATIVES. SM Awad, NM Ahmed, HR Haffez Pharmacophore, 2018 | 6 | 2018 |
IN-VITRO SCREENING OF SOME PLANT EXTRACTS FOR THEIR POTENTIAL ANTICANCER ACTIVITY ZAH Hassan Yahia Ebrahim, Shaimaa Abdelrheem Osman, Hesham Raffat Haffez African Journal of Traditional, Complementary and Alternative Medicines 17 …, 2020 | 5 | 2020 |
Is Cystatin C a powerful Predictor of Cardiovascular Diseases in patients with type 2 Diabetes Mellitus?(Study on Egyptian patients) H Rafat, SH Soror, Z Hassan, A Ismaail Journal of Applied Pharmaceutical Science, 54-58, 2011 | 3 | 2011 |
Novel N-Arylmethyl-aniline/chalcone hybrids as potential VEGFR inhibitors: synthesis, biological evaluations, and molecular dynamic simulations H Haffez, NA Elsayed, MF Ahmed, SS Fatahala, EF Khaleel, RM Badi, ... Journal of Enzyme Inhibition and Medicinal Chemistry 38 (1), 2278022, 2023 | 2 | 2023 |
New phenothiazine conjugates as apoptosis inducing agents: Design, synthesis, In-vitro anti-cancer screening and 131I-radiolabeling for in-vivo evaluation WAZ Mona O. Sarhan, Hesham Haffez, Nosaiba A. Elsayed, Radwan S. El-Haggar Bioorganic Chemistry 141, 2023 | 2 | 2023 |
Common applications of black cumin Seed (Nigella sativa) oil in folk medicine R Hosni, H Haffez, H Elkordy Journal of Advanced Pharmacy Research 7 (1), 1-14, 2023 | 2 | 2023 |
Augmented Therapeutic Potential of EC-Synthetic Retinoids in Caco-2 Cancer Cells Using an In Vitro Approach RA Mohamed, I Esraa, RE Mohamed, HS Sameh, H Haffez International journal of molecular sciences 23 (16), 9442, 2022 | 2 | 2022 |
Role of single nucleotide polymorphisms of the HSD3B1 gene (rs6203 and rs33937873) in the prediction of prostate cancer risk A Yasmine M., H Haffez, A Doaa M., HB Atya Molecular Medicine Reports 26 (2), 9, 2022 | 2* | 2022 |