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Jinyuan Sun
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Computational enzyme redesign: large jumps in function
Y Cui, J Sun, B Wu
Trends in Chemistry 4 (5), 409-419, 2022
332022
Exploration of transaminase diversity for the oxidative conversion of natural amino acids into 2-ketoacids and high-value chemicals
T Li, X Cui, Y Cui, J Sun, Y Chen, T Zhu, C Li, R Li, B Wu
ACS Catalysis 10 (14), 7950-7957, 2020
192020
Structure prediction of the entire proteome of monkeypox variants
L Zheng, J Meng, M Lin, R Lv, H Cheng, L Zou, J Sun, LX Li, R Ren, ...
Acta Materia Medica 1 (2), 260-264, 2022
182022
Whole-Genome Sequencing and Bioinformatics Analysis of Apiotrichum mycotoxinivorans: Predicting Putative Zearalenone-Degradation Enzymes
J Sun, Y Xia, D Ming
Frontiers in Microbiology 11, 1866, 2020
172020
Characterization and efficient production of a thermostable, halostable and organic solvent-stable cellulase from an oil reservoir
T Zhu, R Li, J Sun, Y Cui, B Wu
International journal of biological macromolecules 159, 622-629, 2020
162020
GRAPE, a greedy accumulated strategy for computational protein engineering
J Sun, Y Cui, B Wu
Methods in enzymology 648, 207-230, 2021
132021
Computational redesign of a hydrolase for nearly complete PET depolymerization at industrially relevant high-solids loading
Y Cui, Y Chen, J Sun, T Zhu, H Pang, C Li, WC Geng, B Wu
Nature Communications 15 (1), 1417, 2024
112024
Strategies for enhancing eicosapentaenoic acid production: from fermentation to metabolic engineering
Y Xia, YT Zhang, JY Sun, H Huang, Q Zhao, LJ Ren
Algal Research 51, 102038, 2020
62020
Mutation of Stevia glycosyltransferase UGT76G1 for efficient biotransformation of rebaudioside E into rebaudioside M
J Yu, Y Tao, H Pan, L Lin, J Sun, R Ma, Y Li, H Jia
Journal of Functional Foods 92, 105033, 2022
52022
Engineered DNase-inactive Cpf1 variants to improve targeting scope for base editing in E. coli
Z Chen, J Sun, Y Guan, M Li, C Lou, B Wu
Synthetic and Systems Biotechnology 6 (4), 326-334, 2021
52021
zPoseScore model for accurate and robust protein–ligand docking pose scoring in CASP15
T Shen, F Liu, Z Wang, J Sun, Y Bu, J Meng, W Chen, K Yao, Y Mu, W Li, ...
Proteins: Structure, Function, and Bioinformatics 91 (12), 1837-1849, 2023
42023
Insights into the biosynthesis of septacidin l-heptosamine moiety unveils a VOC family sugar epimerase
M Chen, Z Guo, J Sun, W Tang, M Wang, Y Tang, P Li, B Wu, Y Chen
Acta Pharmaceutica Sinica B 13 (2), 765-774, 2023
42023
Deep learning-aided redesign of a hydrolase for near 100% PET depolymerization under industrially relevant conditions
B Wu, Y Cui, Y Chen, J Sun, T Zhu, H Pang, C Li, W Geng
42023
Computational Enzyme Redesign Enhances Tolerance to Denaturants for Peptide C-Terminal Amidation
T Zhu, J Sun, H Pang, B Wu
JACS Au 4 (2), 788-797, 2024
12024
Design of synthetic biology components based on artificial intelligence and computational biology
W Sheng, W Zechen, C Weihua, C Ke, P Xiangda, OU Fafen, ...
Synthetic Biology Journal 4 (3), 422, 2023
12023
基于人工智能和计算生物学的合成生物学元件设计
王晟, 王泽琛, 陈威华, 陈珂, 彭向达, 欧发芬, 郑良振, 孙瑨原, 沈涛, ...
合成生物学 4 (3), 422, 2023
12023
Structure-based self-supervised learning enables ultrafast prediction of stability changes upon mutation at the protein universe scale
J Sun, T Zhu, Y Cui, B Wu
bioRxiv, 2023.08. 09.552725, 2023
12023
Protein design with a machine-learned potential about backbone designability
J Sun, B Wu
Trends in Biochemical Sciences 47 (8), 638-640, 2022
12022
Structure motif guided mining of MHET hydrolase and development of a two-enzyme cascade for plastics depolymerization at mild temperature
X Liu, W Geng, J Sun, Z Chen, Y Cui, B Wu
Sheng wu Gong Cheng xue bao= Chinese Journal of Biotechnology 40 (3), 773-785, 2024
2024
Structure-based self-supervised learning enables ultrafast prediction of stability changes upon mutation
J Sun, T Zhu, Y Cui, B Wu
2023
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