Computational enzyme redesign: large jumps in function Y Cui, J Sun, B Wu Trends in Chemistry 4 (5), 409-419, 2022 | 33 | 2022 |
Exploration of transaminase diversity for the oxidative conversion of natural amino acids into 2-ketoacids and high-value chemicals T Li, X Cui, Y Cui, J Sun, Y Chen, T Zhu, C Li, R Li, B Wu ACS Catalysis 10 (14), 7950-7957, 2020 | 19 | 2020 |
Structure prediction of the entire proteome of monkeypox variants L Zheng, J Meng, M Lin, R Lv, H Cheng, L Zou, J Sun, LX Li, R Ren, ... Acta Materia Medica 1 (2), 260-264, 2022 | 18 | 2022 |
Whole-Genome Sequencing and Bioinformatics Analysis of Apiotrichum mycotoxinivorans: Predicting Putative Zearalenone-Degradation Enzymes J Sun, Y Xia, D Ming Frontiers in Microbiology 11, 1866, 2020 | 17 | 2020 |
Characterization and efficient production of a thermostable, halostable and organic solvent-stable cellulase from an oil reservoir T Zhu, R Li, J Sun, Y Cui, B Wu International journal of biological macromolecules 159, 622-629, 2020 | 16 | 2020 |
GRAPE, a greedy accumulated strategy for computational protein engineering J Sun, Y Cui, B Wu Methods in enzymology 648, 207-230, 2021 | 13 | 2021 |
Computational redesign of a hydrolase for nearly complete PET depolymerization at industrially relevant high-solids loading Y Cui, Y Chen, J Sun, T Zhu, H Pang, C Li, WC Geng, B Wu Nature Communications 15 (1), 1417, 2024 | 11 | 2024 |
Strategies for enhancing eicosapentaenoic acid production: from fermentation to metabolic engineering Y Xia, YT Zhang, JY Sun, H Huang, Q Zhao, LJ Ren Algal Research 51, 102038, 2020 | 6 | 2020 |
Mutation of Stevia glycosyltransferase UGT76G1 for efficient biotransformation of rebaudioside E into rebaudioside M J Yu, Y Tao, H Pan, L Lin, J Sun, R Ma, Y Li, H Jia Journal of Functional Foods 92, 105033, 2022 | 5 | 2022 |
Engineered DNase-inactive Cpf1 variants to improve targeting scope for base editing in E. coli Z Chen, J Sun, Y Guan, M Li, C Lou, B Wu Synthetic and Systems Biotechnology 6 (4), 326-334, 2021 | 5 | 2021 |
zPoseScore model for accurate and robust protein–ligand docking pose scoring in CASP15 T Shen, F Liu, Z Wang, J Sun, Y Bu, J Meng, W Chen, K Yao, Y Mu, W Li, ... Proteins: Structure, Function, and Bioinformatics 91 (12), 1837-1849, 2023 | 4 | 2023 |
Insights into the biosynthesis of septacidin l-heptosamine moiety unveils a VOC family sugar epimerase M Chen, Z Guo, J Sun, W Tang, M Wang, Y Tang, P Li, B Wu, Y Chen Acta Pharmaceutica Sinica B 13 (2), 765-774, 2023 | 4 | 2023 |
Deep learning-aided redesign of a hydrolase for near 100% PET depolymerization under industrially relevant conditions B Wu, Y Cui, Y Chen, J Sun, T Zhu, H Pang, C Li, W Geng | 4 | 2023 |
Computational Enzyme Redesign Enhances Tolerance to Denaturants for Peptide C-Terminal Amidation T Zhu, J Sun, H Pang, B Wu JACS Au 4 (2), 788-797, 2024 | 1 | 2024 |
Design of synthetic biology components based on artificial intelligence and computational biology W Sheng, W Zechen, C Weihua, C Ke, P Xiangda, OU Fafen, ... Synthetic Biology Journal 4 (3), 422, 2023 | 1 | 2023 |
基于人工智能和计算生物学的合成生物学元件设计 王晟, 王泽琛, 陈威华, 陈珂, 彭向达, 欧发芬, 郑良振, 孙瑨原, 沈涛, ... 合成生物学 4 (3), 422, 2023 | 1 | 2023 |
Structure-based self-supervised learning enables ultrafast prediction of stability changes upon mutation at the protein universe scale J Sun, T Zhu, Y Cui, B Wu bioRxiv, 2023.08. 09.552725, 2023 | 1 | 2023 |
Protein design with a machine-learned potential about backbone designability J Sun, B Wu Trends in Biochemical Sciences 47 (8), 638-640, 2022 | 1 | 2022 |
Structure motif guided mining of MHET hydrolase and development of a two-enzyme cascade for plastics depolymerization at mild temperature X Liu, W Geng, J Sun, Z Chen, Y Cui, B Wu Sheng wu Gong Cheng xue bao= Chinese Journal of Biotechnology 40 (3), 773-785, 2024 | | 2024 |
Structure-based self-supervised learning enables ultrafast prediction of stability changes upon mutation J Sun, T Zhu, Y Cui, B Wu | | 2023 |