Induction of complete and molecular remissions in acute myeloid leukemia by Wilms’ tumor 1 antigen-targeted dendritic cell vaccination VF Van Tendeloo, A Van de Velde, A Van Driessche, N Cools, S Anguille, ... Proceedings of the National Academy of Sciences 107 (31), 13824-13829, 2010 | 458 | 2010 |
Balancing between immunity and tolerance: an interplay between dendritic cells, regulatory T cells, and effector T cells N Cools, P Ponsaerts, VFI Van Tendeloo, ZN Berneman Journal of Leucocyte Biology 82 (6), 1365-1374, 2007 | 377 | 2007 |
Regulatory T cells and human disease N Cools, P Ponsaerts, VFI Van Tendeloo, ZN Berneman Clinical and Developmental Immunology 2007, 2007 | 311 | 2007 |
Dendritic cell vaccination as postremission treatment to prevent or delay relapse in acute myeloid leukemia S Anguille, AL Van de Velde, EL Smits, VF Van Tendeloo, G Juliusson, ... Blood, The Journal of the American Society of Hematology 130 (15), 1713-1721, 2017 | 196 | 2017 |
Hurdles in therapy with regulatory T cells P Trzonkowski, R Bacchetta, M Battaglia, D Berglund, HR Bohnenkamp, ... Science translational medicine 7 (304), 304ps18-304ps18, 2015 | 167 | 2015 |
Cytomegalovirus-associated accumulation of late-differentiated CD4 T-cells correlates with poor humoral response to influenza vaccination E Derhovanessian, H Theeten, K Hähnel, P Van Damme, N Cools, ... Vaccine 31 (4), 685-690, 2013 | 140 | 2013 |
Messenger RNA electroporation of human monocytes, followed by rapid in vitro differentiation, leads to highly stimulatory antigen-loaded mature dendritic cells P Ponsaerts, G Van den Bosch, N Cools, A Van Driessche, G Nijs, ... The Journal of Immunology 169 (4), 1669-1675, 2002 | 139 | 2002 |
The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein KO De Beeck, G Van Camp, S Thys, N Cools, I Callebaut, K Vrijens, ... European Journal of Human Genetics 19 (9), 965-973, 2011 | 124 | 2011 |
Immunosuppression induced by immature dendritic cells is mediated by TGF‐β/IL‐10 double‐positive CD4+ regulatory T cells N Cools, VFI Van Tendeloo, E Smits, M Lenjou, G Nijs, ... Journal of cellular and molecular medicine 12 (2), 690-700, 2008 | 120 | 2008 |
Tolerogenic dendritic cell vaccines to treat autoimmune diseases: can the unattainable dream turn into reality? I Van Brussel, WP Lee, M Rombouts, AH Nuyts, M Heylen, BY De Winter, ... Autoimmunity reviews 13 (2), 138-150, 2014 | 112 | 2014 |
mRNA-based dendritic cell vaccination induces potent antiviral T-cell responses in HIV-1-infected patients E Van Gulck, E Vlieghe, M Vekemans, VFI Van Tendeloo, A Van De Velde, ... Aids 26 (4), F1-F12, 2012 | 112 | 2012 |
Short-term cultured, interleukin-15 differentiated dendritic cells have potent immunostimulatory properties S Anguille, ELJM Smits, N Cools, H Goossens, ZN Berneman, ... Journal of translational medicine 7 (1), 1-16, 2009 | 110 | 2009 |
Dendritic cells: cellular mediators for immunological tolerance CYJ Chung, D Ysebaert, ZN Berneman, N Cools Clinical and developmental immunology 2013, 2013 | 106 | 2013 |
Dendritic cells in multiple sclerosis: key players in the immunopathogenesis, key players for new cellular immunotherapies? AH Nuyts, WP Lee, R Bashir-Dar, ZN Berneman, N Cools Multiple Sclerosis Journal 19 (8), 995-1002, 2013 | 106 | 2013 |
Dendritic cell-based cancer gene therapy ELJM Smits, S Anguille, N Cools, ZN Berneman, VFI Van Tendeloo Human gene therapy 20 (10), 1106-1118, 2009 | 84 | 2009 |
Optimizing dendritic cell-based immunotherapy: tackling the complexity of different arms of the immune system I Van Brussel, ZN Berneman, N Cools Mediators of inflammation 2012, 2012 | 75 | 2012 |
The Toll-like receptor 7/8 agonist resiquimod greatly increases the immunostimulatory capacity of human acute myeloid leukemia cells ELJM Smits, N Cools, E Lion, K Van Camp, P Ponsaerts, ZN Berneman, ... Cancer Immunology, Immunotherapy 59, 35-46, 2010 | 75 | 2010 |
Neuroendocrine immunoregulation in multiple sclerosis N Deckx, WP Lee, ZN Berneman, N Cools Journal of Immunology Research 2013, 2013 | 72 | 2013 |
mRNA-electroporated mature dendritic cells retain transgene expression, phenotypical properties and stimulatory capacity after cryopreservation P Ponsaerts, VFI Van Tendeloo, N Cools, A Van Driessche, F Lardon, ... Leukemia 16 (7), 1324-1330, 2002 | 69 | 2002 |
Tolerogenic dendritic cell-based treatment for multiple sclerosis (MS): a harmonised study protocol for two phase I clinical trials comparing intradermal and intranodal cell … B Willekens, S Presas-Rodríguez, MJ Mansilla, J Derdelinckx, WP Lee, ... BMJ open 9 (9), e030309, 2019 | 68 | 2019 |