An internal ligand-bound, metastable state of a leukocyte integrin, αXβ2 M Sen, K Yuki, TA Springer The Journal of cell biology 203 (4), 629, 2013 | 107 | 2013 |
Neutralizing aptamers block S/RBD‐ACE2 interactions and prevent host cell infection X Liu, Y Wang, J Wu, J Qi, Z Zeng, Q Wan, Z Chen, P Manandhar, ... Angewandte Chemie International Edition 60 (18), 10273-10278, 2021 | 98 | 2021 |
A lupus-associated Mac-1 variant has defects in integrin allostery and interaction with ligands under force F Rosetti, Y Chen, M Sen, E Thayer, V Azcutia, JM Herter, FW Luscinskas, ... Cell reports 10 (10), 1655-1664, 2015 | 77 | 2015 |
LFA-1 affinity regulation is necessary for the activation and proliferation of naive T cells Y Wang, D Li, R Nurieva, J Yang, M Sen, R Carreno, S Lu, BW McIntyre, ... Journal of Biological Chemistry 284 (19), 12645-12653, 2009 | 67 | 2009 |
Cis interaction between sialylated FcγRIIA and the αI-domain of Mac-1 limits antibody-mediated neutrophil recruitment G Saggu, K Okubo, Y Chen, R Vattepu, N Tsuboi, F Rosetti, X Cullere, ... Nature communications 9 (1), 5058, 2018 | 53 | 2018 |
Leukocyte integrin αLβ2 headpiece structures: The αI domain, the pocket for the internal ligand, and concerted movements of its loops M Sen, TA Springer Proceedings of the National Academy of Sciences 113 (11), 2940-2945, 2016 | 51 | 2016 |
Isoflurane binds and stabilizes a closed conformation of the leukocyte function-associated antigen-1 K Yuki, W Bu, J Xi, M Sen, M Shimaoka, RG Eckenhoff The FASEB Journal 26 (11), 4408, 2012 | 48 | 2012 |
Estrogen receptor beta-mediated modulation of lung cancer cell proliferation by 27-hydroxycholesterol S Hiramitsu, T Ishikawa, WR Lee, T Khan, C Crumbley, N Khwaja, ... Frontiers in endocrinology 9, 470, 2018 | 39 | 2018 |
Ligand-and cation-induced structural alterations of the leukocyte integrin LFA-1 M Sen, AC Koksal, K Yuki, J Wang, TA Springer Journal of Biological Chemistry 293 (17), 6565-6577, 2018 | 33 | 2018 |
Complement receptor 3 forms a compact high-affinity complex with iC3b RK Jensen, G Bajic, M Sen, TA Springer, T Vorup-Jensen, GR Andersen The Journal of Immunology 206 (12), 3032-3042, 2021 | 31 | 2021 |
Spectroscopic characterization of successive phosphorylation of the tissue factor cytoplasmic region M Sen, M Herzik Jr, JW Craft Jr, AL Creath, S Agrawal, W Ruf, GB Legge The open spectroscopy journal 3, 58, 2009 | 27 | 2009 |
Activated β2 Integrins Restrict Neutrophil Recruitment during Murine Acute Pseudomonal Pneumonia ZS Wilson, LB Ahn, WS Serratelli, MD Belley, J Lomas-Neira, M Sen, ... American Journal of Respiratory Cell and Molecular Biology 56 (5), 620-627, 2017 | 20 | 2017 |
Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity K Kurakula, DS Koenis, MA Herzik Jr, Y Liu, JW Craft Jr, PB van Loenen, ... Haematologica 103 (6), 1073, 2018 | 18 | 2018 |
A mechanism for antibody-mediated outside-in activation of LFA-1 R Carreno, D Li, M Sen, I Nira, T Yamakawa, Q Ma, GB Legge Journal of Biological Chemistry 283 (16), 10642-10648, 2008 | 11 | 2008 |
Expression and Characterization of Intein-Cyclized Trimer of Staphylococcus aureus Protein A Domain Z S Nandy, VM Maranholkar, M Crum, K Wasden, U Patil, A Goyal, B Vu, ... International journal of molecular sciences 24 (2), 1281, 2023 | 6 | 2023 |
Pactolus I‐domain: Functional switching of the Rossmann fold M Sen, GB Legge Proteins: Structure, Function, and Bioinformatics 68 (3), 626-635, 2007 | 6 | 2007 |
Systematic mapping of the conformational landscape and dynamism of soluble fibrinogen JEE Pinelo, P Manandhar, G Popovic, K Ray, MF Tasdelen, Q Nguyen, ... Journal of Thrombosis and Haemostasis 21 (6), 1529-1543, 2023 | 5 | 2023 |
New Emerging Biotherapies: Cutting‐Edge Research to Experimental Therapies V Kayser, M Sen Biologics, Biosimilars, and Biobetters: An Introduction for Pharmacists …, 2020 | 3 | 2020 |
Full-length αIIbβ3 cryo-EM structure reveals intact integrin initiate-activation intrinsic architecture T Huo, H Wu, Z Moussa, M Sen, V Dalton, Z Wang Structure, 2024 | 2 | 2024 |
Interplay between intrinsic flexibility and sugar coating in Contactin-2 homodimerization M Sen Structure 32 (1), 3-5, 2024 | 2 | 2024 |