Improved survival and reduced phenotypic severity following AAV9/MECP2 gene transfer to neonatal and juvenile male Mecp2 knockout mice KKE Gadalla, MES Bailey, RC Spike, PD Ross, KT Woodard, SN Kalburgi, ... Molecular Therapy 21 (1), 18-30, 2013 | 172 | 2013 |
Radically truncated MeCP2 rescues Rett syndrome-like neurological defects R Tillotson, J Selfridge, MV Koerner, KKE Gadalla, J Guy, D De Sousa, ... Nature 550 (7676), 398-401, 2017 | 154 | 2017 |
MeCP2 and Rett syndrome: reversibility and potential avenues for therapy KKE Gadalla, MES Bailey, SR Cobb Biochemical Journal 439 (1), 1-14, 2011 | 139 | 2011 |
Development of a novel AAV gene therapy cassette with improved safety features and efficacy in a mouse model of Rett syndrome KKE Gadalla, T Vudhironarit, RD Hector, S Sinnett, NG Bahey, ... Molecular Therapy Methods & Clinical Development 5, 180-190, 2017 | 99 | 2017 |
Improved MECP2 gene therapy extends the survival of MeCP2-null mice without apparent toxicity after intracisternal delivery SE Sinnett, RD Hector, KKE Gadalla, C Heindel, D Chen, V Zaric, ... Molecular Therapy Methods & Clinical Development 5, 106-115, 2017 | 86 | 2017 |
Inhibition of Piezo1 attenuates demyelination in the central nervous system M Velasco‐Estevez, KKE Gadalla, N Liñan‐Barba, S Cobb, KK Dev, ... Glia 68 (2), 356-375, 2020 | 64 | 2020 |
Toxic effect of aflatoxin B1 and the role of recovery on the rat cerebral cortex and hippocampus NG Bahey, HO Abd Elaziz, KKES Gadalla Tissue and cell 47 (6), 559-566, 2015 | 46 | 2015 |
Gait analysis in a Mecp2 knockout mouse model of Rett syndrome reveals early-onset and progressive motor deficits KKE Gadalla, PD Ross, JS Riddell, MES Bailey, SR Cobb PloS one 9 (11), e112889, 2014 | 32 | 2014 |
Potential toxic effect of bisphenol A on the cardiac muscle of adult rat and the possible protective effect of Omega-3: a histological and immunohistochemical study NG Bahey, HO Abd Elaziz, KKE Gadalla Journal of microscopy and ultrastructure 7 (1), 1-8, 2019 | 30 | 2019 |
Cancer immunology N Rezaei Springer, 2015 | 24* | 2015 |
Gene therapy for Rett syndrome: prospects and challenges KKE Gadalla, PD Ross, RD Hector, NG Bahey, MES Bailey, SR Cobb Future Neurology 10 (5), 467-484, 2015 | 16 | 2015 |
Novel MECP2 gene therapy is effective in a multicenter study using two mouse models of Rett syndrome and is safe in non-human primates S Powers, S Likhite, KK Gadalla, CJ Miranda, AJ Huffenberger, C Dennys, ... Molecular Therapy 31 (9), 2767-2782, 2023 | 6 | 2023 |
Label-free imaging of thick tissue at 1550 nm using a femtosecond optical parametric generator J Trägårdh, G Robb, KKE Gadalla, S Cobb, C Travis, GL Oppo, ... Optics Letters 40 (15), 3484-3487, 2015 | 6 | 2015 |
Reduced axonal diameter of peripheral nerve fibers in a mouse model of Rett syndrome NG Bahey, KKE Gadalla, R McGonigal, MES Bailey, JM Edgar, SR Cobb Neuroscience 358, 261-268, 2017 | 4 | 2017 |
Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome SA Zlatic, D Duong, KKE Gadalla, B Murage, L Ping, R Shah, JJ Fink, ... Iscience 25 (9), 2022 | 3 | 2022 |
Gene therapy and virus-based cancer vaccines ML Salem, KKE Gadalla, BC Fielding, SH Thorne Cancer Immunology: Bench to Bedside Immunotherapy of Cancers, 131-150, 2015 | 2 | 2015 |
Cancer vaccines DF Hale, GT Clifton, AK Sears, TJ Vreeland, N Shumway, GE Peoples, ... should we be targeting patients with less aggressive disease? 2012, 11, 0 | 2 | |
Virus-mediated delivery of MECP2 as a potential tool for the treatment of Rett syndrome KKES Gadalla Institute of Neuroscience and Psychology, 2012 | 1 | 2012 |
An EXACT single gene circuit improves the safety of vector-derived MeCP2 expression in vivo KK Gadalla, NG Bahey, S Thomson, P Ross, RD Hector, J Selfridge, ... HUMAN GENE THERAPY 33 (23-24), A84-A84, 2022 | | 2022 |
Gene transfer rescues audiogenic seizures in a mouse model of Fragile X syndrome LC Kaminioti-Dumont, KK Gadalla, RD Hector, J Selfridge, E Osterweil, ... HUMAN GENE THERAPY 33 (23-24), A84-A84, 2022 | | 2022 |