| Oxidative stress activates a positive feedback between the γ‐and β‐secretase cleavages of the β‐amyloid precursor protein E Tamagno, M Guglielmotto, M Aragno, R Borghi, R Autelli, L Giliberto, ... Journal of neurochemistry 104 (3), 683-695, 2008 | 415 | 2008 |
| β‐Site APP cleaving enzyme up‐regulation induced by 4‐hydroxynonenal is mediated by stress‐activated protein kinases pathways E Tamagno, M Parola, P Bardini, A Piccini, R Borghi, M Guglielmotto, ... Journal of neurochemistry 92 (3), 628-636, 2005 | 400 | 2005 |
| The up‐regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1α M Guglielmotto, M Aragno, R Autelli, L Giliberto, E Novo, S Colombatto, ... Journal of neurochemistry 108 (4), 1045-1056, 2009 | 274 | 2009 |
| AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation M Guglielmotto, M Aragno, E Tamagno, I Vercellinatto, S Visentin, ... Neurobiology of aging 33 (1), 196. e13-196. e27, 2012 | 176 | 2012 |
| Multiple signaling events in amyloid β-induced, oxidative stress-dependent neuronal apoptosis E Tamagno, M Parola, M Guglielmotto, G Santoro, P Bardini, L Marra, ... Free Radical Biology and Medicine 35 (1), 45-58, 2003 | 172 | 2003 |
| The various aggregation states of β-amyloid 1–42 mediate different effects on oxidative stress, neurodegeneration, and BACE-1 expression E Tamagno, P Bardini, M Guglielmotto, O Danni, M Tabaton Free Radical Biology and Medicine 41 (2), 202-212, 2006 | 167 | 2006 |
| Oxidative stress mediates the pathogenic effect of different Alzheimer's disease risk factors M Guglielmotto, L Giliberto, E Tamagno, M Tabaton Frontiers in aging neuroscience 2, 1276, 2010 | 165 | 2010 |
| Interaction between 24‐hydroxycholesterol, oxidative stress, and amyloid‐β in amplifying neuronal damage in Alzheimer’s disease: three partners in crime P Gamba, G Leonarduzzi, E Tamagno, M Guglielmotto, G Testa, B Sottero, ... Aging Cell 10 (3), 403-417, 2011 | 125 | 2011 |
| Oxidative stress and beta amyloid in Alzheimer’s disease. Which comes first: the chicken or the egg? E Tamagno, M Guglielmotto, V Vasciaveo, M Tabaton Antioxidants 10 (9), 1479, 2021 | 108 | 2021 |
| Amyloid-β production: major link between oxidative stress and BACE1 E Tamagno, M Guglielmotto, D Monteleone, M Tabaton Neurotoxicity research 22, 208-219, 2012 | 108 | 2012 |
| Oxidative stress and hypoxia contribute to Alzheimer′ s disease pathogenesis: two sides of the same coin M Guglielmotto, E Tamagno, O Danni The Scientific World Journal 9 (1), 781-791, 2009 | 107 | 2009 |
| Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis M Guglielmotto, D Monteleone, A Piras, V Valsecchi, M Tropiano, ... Autophagy 10 (10), 1827-1843, 2014 | 91 | 2014 |
| JNK and ERK1/2 pathways have a dual opposite effect on the expression of BACE1 E Tamagno, M Guglielmotto, L Giliberto, A Vitali, R Borghi, R Autelli, ... Neurobiology of aging 30 (10), 1563-1573, 2009 | 86 | 2009 |
| KRIT1 loss of function causes a ROS-dependent upregulation of c-Jun L Goitre, E De Luca, S Braggion, E Trapani, M Guglielmotto, F Biasi, ... Free Radical Biology and Medicine 68, 134-147, 2014 | 85 | 2014 |
| Mutant presenilin 1 increases the expression and activity of BACE1 L Giliberto, R Borghi, A Piccini, R Mangerini, S Sorbi, G Cirmena, A Garuti, ... Journal of Biological Chemistry 284 (14), 9027-9038, 2009 | 76 | 2009 |
| Extracellular self-DNA (esDNA), but not heterologous plant or insect DNA (etDNA), induces plasma membrane depolarization and calcium signaling in lima bean (Phaseolus lunatus … F Barbero, M Guglielmotto, A Capuzzo, ME Maffei International Journal of Molecular Sciences 17 (10), 1659, 2016 | 74 | 2016 |
| Aβ1‐42‐mediated down‐regulation of Uch‐L1 is dependent on NF‐κB activation and impaired BACE1 lysosomal degradation M Guglielmotto, D Monteleone, M Boido, A Piras, L Giliberto, R Borghi, ... Aging cell 11 (5), 834-844, 2012 | 67 | 2012 |
| Amyloid-β 42 activates the expression of BACE1 through the JNK pathway M Guglielmotto, D Monteleone, L Giliberto, M Fornaro, R Borghi, ... Journal of Alzheimer's Disease 27 (4), 871-883, 2011 | 67 | 2011 |
| Up‐regulation of β‐amyloidogenesis in neuron‐like human cells by both 24‐ and 27‐hydroxycholesterol: protective effect of N‐acetyl‐cysteine P Gamba, M Guglielmotto, G Testa, D Monteleone, C Zerbinati, S Gargiulo, ... Aging cell 13 (3), 561-572, 2014 | 62 | 2014 |
| Inhibition of autophagy delays motoneuron degeneration and extends lifespan in a mouse model of spinal muscular atrophy A Piras, L Schiaffino, M Boido, V Valsecchi, M Guglielmotto, E De Amicis, ... Cell death & disease 8 (12), 3223, 2017 | 55 | 2017 |
