Turning cold into hot: firing up the tumor microenvironment Q Duan, H Zhang, J Zheng, L Zhang Trends in cancer 6 (7), 605-618, 2020 | 682 | 2020 |
TSC1 controls macrophage polarization to prevent inflammatory disease L Zhu, T Yang, L Li, L Sun, Y Hou, X Hu, L Zhang, H Tian, Q Zhao, J Peng, ... Nature communications 5 (1), 4696, 2014 | 296 | 2014 |
The imbalance of Th17/Th1/Tregs in patients with type 2 diabetes: relationship with metabolic factors and complications C Zeng, X Shi, B Zhang, H Liu, L Zhang, W Ding, Y Zhao Journal of molecular medicine 90, 175-186, 2012 | 268 | 2012 |
The regulation of Foxp3 expression in regulatory CD4+CD25+T cells: Multiple pathways on the road L Zhang, Y Zhao Journal of cellular physiology 211 (3), 590-597, 2007 | 226 | 2007 |
Metabolic control of CD8+ T cell fate decisions and antitumor immunity L Zhang, P Romero Trends in molecular medicine 24 (1), 30-48, 2018 | 192 | 2018 |
The NAD-booster nicotinamide riboside potently stimulates hematopoiesis through increased mitochondrial clearance N Vannini, V Campos, M Girotra, V Trachsel, S Rojas-Sutterlin, J Tratwal, ... Cell stem cell 24 (3), 405-418. e7, 2019 | 183 | 2019 |
Mitochondria-endoplasmic reticulum contact sites function as immunometabolic hubs that orchestrate the rapid recall response of memory CD8+ T cells GR Bantug, M Fischer, J Grählert, ML Balmer, G Unterstab, L Develioglu, ... Immunity 48 (3), 542-555. e6, 2018 | 146 | 2018 |
Mammalian target of rapamycin complex 2 controls CD8 T cell memory differentiation in a Foxo1-dependent manner L Zhang, BO Tschumi, IC Lopez-Mejia, SG Oberle, M Meyer, G Samson, ... Cell reports 14 (5), 1206-1217, 2016 | 136 | 2016 |
Modulation of immune responses through direct activation of Toll-like receptors to T cells G Liu, L Zhang, Y Zhao Clinical & Experimental Immunology 160 (2), 168-175, 2010 | 136 | 2010 |
Modulation of mTOR signalling triggers the formation of stem cell-like memory T cells G Scholz, C Jandus, L Zhang, C Grandclément, IC Lopez-Mejia, ... EBioMedicine 4, 50-61, 2016 | 115 | 2016 |
Transforming growth factor-beta: An important role in CD4+CD25+ regulatory T cells and immune tolerance L Zhang, H Yi, XP Xia, Y Zhao Autoimmunity 39 (4), 269-276, 2006 | 106 | 2006 |
Enforced PGC-1α expression promotes CD8 T cell fitness, memory formation and antitumor immunity N Dumauthioz, B Tschumi, M Wenes, B Marti, H Wang, F Franco, W Li, ... Cellular & molecular immunology 18 (7), 1761-1771, 2021 | 90 | 2021 |
CDK4 is an essential insulin effector in adipocytes S Lagarrigue, IC Lopez-Mejia, PD Denechaud, X Escoté, ... The Journal of clinical investigation 126 (1), 335-348, 2022 | 84 | 2022 |
Immunotoxic effects of perfluorononanoic acid on BALB/c mice X Fang, L Zhang, Y Feng, Y Zhao, J Dai Toxicological Sciences 105 (2), 312-321, 2008 | 84 | 2008 |
The mitochondrial pyruvate carrier regulates memory T cell differentiation and antitumor function M Wenes, A Jaccard, T Wyss, N Maldonado-Pérez, ST Teoh, A Lepez, ... Cell Metabolism 34 (5), 731-746. e9, 2022 | 81 | 2022 |
CART cells are prone to Fas-and DR5-mediated cell death BO Tschumi, N Dumauthioz, B Marti, L Zhang, P Schneider, JP Mach, ... Journal for immunotherapy of cancer 6 (1), 71, 2018 | 80 | 2018 |
Tanycytes regulate lipid homeostasis by sensing free fatty acids and signaling to key hypothalamic neuronal populations via FGF21 secretion S Geller, Y Arribat, C Netzahualcoyotzi, S Lagarrigue, L Carneiro, ... Cell metabolism 30 (4), 833-844. e7, 2019 | 74 | 2019 |
CDK4 phosphorylates AMPKα2 to inhibit its activity and repress fatty acid oxidation IC Lopez-Mejia, S Lagarrigue, A Giralt, L Martinez-Carreres, N Zanou, ... Molecular cell 68 (2), 336-349. e6, 2017 | 74 | 2017 |
Mammalian target of rapamycin complex 1 orchestrates invariant NKT cell differentiation and effector function L Zhang, BO Tschumi, S Corgnac, MA Rüegg, MN Hall, JP Mach, ... The Journal of Immunology 193 (4), 1759-1765, 2014 | 74 | 2014 |
TSC1/2 signaling complex is essential for peripheral naive CD8+ T cell survival and homeostasis in mice L Zhang, H Zhang, L Li, Y Xiao, E Rao, Z Miao, H Chen, L Sun, H Li, G Liu, ... PloS one 7 (2), e30592, 2012 | 69 | 2012 |