Functionally diverse type V CRISPR-Cas systems WX Yan, P Hunnewell, LE Alfonse, JM Carte, E Keston-Smith, ... Science 363 (6422), 88-91, 2019 | 440 | 2019 |
Peptide design principles for antimicrobial applications MDT Torres, S Sothiselvam, TK Lu, C de la Fuente-Nunez Journal of molecular biology 431 (18), 3547-3567, 2019 | 355 | 2019 |
Macrolide antibiotics allosterically predispose the ribosome for translation arrest S Sothiselvam, B Liu, W Han, H Ramu, D Klepacki, GC Atkinson, A Brauer, ... Proceedings of the National Academy of Sciences 111 (27), 9804-9809, 2014 | 126 | 2014 |
Deregulation of translation due to post-transcriptional modification of rRNA explains why erm genes are inducible P Gupta, S Sothiselvam, N Vázquez-Laslop, AS Mankin Nature communications 4 (1), 1984, 2013 | 74 | 2013 |
Structural and mechanistic basis for translation inhibition by macrolide and ketolide antibiotics B Beckert, EC Leroy, S Sothiselvam, LV Bock, MS Svetlov, M Graf, ... Nature Communications 12 (1), 4466, 2021 | 62 | 2021 |
Binding of macrolide antibiotics leads to ribosomal selection against specific substrates based on their charge and size S Sothiselvam, S Neuner, L Rigger, D Klepacki, R Micura, ... Cell reports 16 (7), 1789-1799, 2016 | 37 | 2016 |
Engineered Cas12i2 is a versatile high-efficiency platform for therapeutic genome editing C McGaw, AJ Garrity, GZ Munoz, JR Haswell, S Sengupta, ... Nature communications 13 (1), 2833, 2022 | 21 | 2022 |
Solid-phase zincke reaction for the synthesis of peptide-4, 4′-bipyridinium Conjugates P Corton, P Novo, V Lopez-Sobrado, MD Garcia, C Peinador, E Pazos Synthesis 52 (04), 537-543, 2020 | 5 | 2020 |
Functional Interactions Between Ribosome and Nascent Peptide Mediated By Small Molecules S Sothiselvam University of Illinois at Chicago, 2016 | | 2016 |
Programmed translation arrest controlling antibiotic resistance genes relies on the sequence context of the nascent peptide stalling domain N Vazquez-Laslop, S Sothiselvam, J Marks, A Mankin FEBS JOURNAL 282, 71-71, 2015 | | 2015 |
The Shortest Nascent Peptide That Can Direct Ribosome Stalling S Sothiselvam, H Ramu, N Vazquez-Laslop, A Mankin The FASEB Journal 26, 550.3-550.3, 2012 | | 2012 |