The fate of chemoresistance in triple negative breast cancer (TNBC) EA O’Reilly, L Gubbins, S Sharma, R Tully, MHZ Guang, K Weiner-Gorzel, ... BBA clinical 3, 257-275, 2015 | 423 | 2015 |
Overexpression of the microRNA miR‐433 promotes resistance to paclitaxel through the induction of cellular senescence in ovarian cancer cells K Weiner‐Gorzel, E Dempsey, M Milewska, A McGoldrick, V Toh, A Walsh, ... Cancer medicine 4 (5), 745-758, 2015 | 173 | 2015 |
Cisplatin induces the release of extracellular vesicles from ovarian cancer cells that can induce invasiveness and drug resistance in bystander cells P Samuel, LA Mulcahy, F Furlong, HO McCarthy, SA Brooks, M Fabbri, ... Philosophical Transactions of the Royal Society B: Biological Sciences 373 …, 2018 | 120 | 2018 |
Connective tissue growth factor [CTGF]/CCN2 stimulates mesangial cell migration through integrated dissolution of focal adhesion complexes and activation of cell polarization JK Crean, F Furlong, D Finlay, D Mitchell, B Conway, HR Brady, ... The FASEB Journal 18 (13), 1541-1543, 2004 | 93 | 2004 |
Low MAD2 expression levels associate with reduced progression‐free survival in patients with high‐grade serous epithelial ovarian cancer F Furlong, P Fitzpatrick, S O'Toole, S Phelan, B McGrogan, A Maguire, ... The Journal of pathology 226 (5), 746-755, 2012 | 88 | 2012 |
Organization of mammary epithelial cells into 3D acinar structures requires glucocorticoid and JNK signaling J Murtagh, E McArdle, E Gilligan, L Thornton, F Furlong, F Martin The Journal of cell biology 166 (1), 133-143, 2004 | 79 | 2004 |
IHG-1 amplifies TGF-β1 signaling and is increased in renal fibrosis M Murphy, NG Docherty, B Griffin, J Howlin, E McArdle, R McMahon, ... Journal of the American Society of Nephrology 19 (9), 1672-1680, 2008 | 64 | 2008 |
FKBPL and its peptide derivatives inhibit endocrine therapy resistant cancer stem cells and breast cancer metastasis by downregulating DLL4 and Notch4 L McClements, S Annett, A Yakkundi, M O’Rourke, A Valentine, ... BMC cancer 19, 1-14, 2019 | 57 | 2019 |
Hollow microneedle assisted intradermal delivery of hypericin lipid nanocapsules with light enabled photodynamic therapy against skin cancer H Abd-El-Azim, IA Tekko, A Ali, A Ramadan, N Nafee, N Khalafallah, ... Journal of Controlled Release 348, 849-869, 2022 | 56 | 2022 |
Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro M Prencipe, P Fitzpatrick, S Gorman, M Tosetto, R Klinger, F Furlong, ... British Journal of Cancer 102 (2), 456, 2010 | 56 | 2010 |
Autophagic secretion of HMGB1 from cancer-associated fibroblasts promotes metastatic potential of non-small cell lung cancer cells via NFκB signaling Y Ren, L Cao, L Wang, S Zheng, Q Zhang, X Guo, X Li, M Chen, X Wu, ... Cell Death & Disease 12 (10), 858, 2021 | 53 | 2021 |
Connective tissue growth factor/CCN2 stimulates actin disassembly through Akt/protein kinase B‐mediated phosphorylation and cytoplasmic translocation of p27Kip‐1 JK Crean, F Furlong, D Mitchell, E McArdle, C Godson, F Martin, JK Crean, ... The FASEB Journal 20 (10), 1712-1714, 2006 | 52 | 2006 |
MAP kinase pathway signalling is essential for extracellular matrix determined mammary epithelial cell survival D Finlay, V Healy, F Furlong, FC O'Connell, NK Keon, F Martin Cell Death & Differentiation 7 (3), 302-313, 2000 | 52 | 2000 |
IHG-1 promotes mitochondrial biogenesis by stabilizing PGC-1α FB Hickey, JB Corcoran, NG Docherty, B Griffin, U Bhreathnach, F Furlong, ... Journal of the American Society of Nephrology 22 (8), 1475-1485, 2011 | 49 | 2011 |
FKBPL-based peptide, ALM201, targets angiogenesis and cancer stem cells in ovarian cancer S Annett, G Moore, A Short, A Marshall, C McCrudden, A Yakkundi, S Das, ... British Journal of Cancer 122 (3), 361-371, 2020 | 48 | 2020 |
Dysregulated intracellular signaling impairs CTGF-stimulated responses in human mesangial cells exposed to high extracellular glucose F Furlong, J Crean, L Thornton, R O'Leary, M Murphy, F Martin American Journal of Physiology-Renal Physiology 292 (6), F1691-F1700, 2007 | 30 | 2007 |
IHG-1 increases mitochondrial fusion and bioenergetic function FB Hickey, JB Corcoran, B Griffin, U Bhreathnach, H Mortiboys, HM Reid, ... Diabetes 63 (12), 4314-4325, 2014 | 28 | 2014 |
IHG-1 must be localised to mitochondria to decrease Smad7 expression and amplify TGF-β1-induced fibrotic responses JB Corcoran, S McCarthy, B Griffin, A Gaffney, U Bhreathnach, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1833 (8), 1969-1978, 2013 | 28 | 2013 |
HDAC6 degradation inhibits the growth of high-grade serous ovarian cancer cells A Ali, F Zhang, A Maguire, T Byrne, K Weiner-Gorzel, S Bridgett, S O’toole, ... Cancers 12 (12), 3734, 2020 | 24 | 2020 |
Too MAD or not MAD enough: The duplicitous role of the spindle assembly checkpoint protein MAD2 in cancer M Bates, F Furlong, MF Gallagher, CD Spillane, A McCann, S O'Toole, ... Cancer Letters 469, 11-21, 2020 | 22 | 2020 |