Merging pathology with biomechanics using CHIMERA (Closed-Head Impact Model of Engineered Rotational Acceleration): a novel, surgery-free model of traumatic brain injury DR Namjoshi, WH Cheng, KA McInnes, KM Martens, M Carr, A Wilkinson, ... Molecular neurodegeneration 9, 1-18, 2014 | 198 | 2014 |
Towards clinical management of traumatic brain injury: a review of models and mechanisms from a biomechanical perspective DR Namjoshi, C Good, WH Cheng, W Panenka, D Richards, PA Cripton, ... Disease models & mechanisms 6 (6), 1325-1338, 2013 | 155 | 2013 |
HFE interacts with the BMP type I receptor ALK3 to regulate hepcidin expression X Wu, Y Wang, Q Wu, WH Cheng, W Liu, Y Zhao, C Mayeur, PJ Schmidt, ... Blood, The Journal of the American Society of Hematology 124 (8), 1335-1343, 2014 | 141 | 2014 |
Reconstituted high-density lipoproteins acutely reduce soluble brain Aβ levels in symptomatic APP/PS1 mice J Robert, S Stukas, E Button, WH Cheng, M Lee, J Fan, A Wilkinson, ... Biochimica Et Biophysica Acta (BBA)-Molecular Basis of Disease 1862 (5 …, 2016 | 87 | 2016 |
Defining the biomechanical and biological threshold of murine mild traumatic brain injury using CHIMERA (Closed Head Impact Model of Engineered Rotational Acceleration) DR Namjoshi, WH Cheng, A Bashir, A Wilkinson, S Stukas, KM Martens, ... Experimental neurology 292, 80-91, 2017 | 85 | 2017 |
CHIMERA repetitive mild traumatic brain injury induces chronic behavioural and neuropathological phenotypes in wild-type and APP/PS1 mice WH Cheng, KM Martens, A Bashir, H Cheung, S Stukas, E Gibbs, ... Alzheimer's research & therapy 11, 1-21, 2019 | 67 | 2019 |
Hepcidin regulation by BMP signaling in macrophages is lipopolysaccharide dependent X Wu, LM Yung, WH Cheng, PB Yu, JL Babitt, HY Lin, Y Xia Public Library of Science 7 (9), e44622, 2012 | 58 | 2012 |
High-density lipoproteins suppress Aβ-induced PBMC adhesion to human endothelial cells in bioengineered vessels and in monoculture J Robert, EB Button, S Stukas, GK Boyce, E Gibbs, CM Cowan, M Gilmour, ... Molecular neurodegeneration 12, 1-19, 2017 | 53 | 2017 |
FE65 interacts with ADP-ribosylation factor 6 to promote neurite outgrowth HNM Cheung, C Dunbar, GM Mórotz, WH Cheng, HYE Chan, CCJ Miller, ... FASEB journal: official publication of the Federation of American Societies …, 2014 | 53 | 2014 |
Age at injury and genotype modify acute inflammatory and neurofilament-light responses to mild CHIMERA traumatic brain injury in wild-type and APP/PS1 mice WH Cheng, S Stukas, KM Martens, DR Namjoshi, EB Button, A Wilkinson, ... Experimental neurology 301, 26-38, 2018 | 46 | 2018 |
Chronic exposure to androgenic-anabolic steroids exacerbates axonal injury and microgliosis in the CHIMERA mouse model of repetitive concussion DR Namjoshi, WH Cheng, M Carr, KM Martens, S Zareyan, A Wilkinson, ... PloS one 11 (1), e0146540, 2016 | 45 | 2016 |
Effect of graft tensioning on mechanical restoration in a rat model of anterior cruciate ligament reconstruction using free tendon graft SC Fu, WH Cheng, YC Cheuk, TY Mok, CG Rolf, SH Yung, KM Chan Knee Surgery, Sports Traumatology, Arthroscopy 21 (5), 1226-1233, 2013 | 43 | 2013 |
Increased severity of the CHIMERA model induces acute vascular injury, sub-acute deficits in memory recall, and chronic white matter gliosis A Bashir, ZA Abebe, KA McInnes, EB Button, I Tatarnikov, WH Cheng, ... Experimental neurology 324, 113116, 2020 | 40 | 2020 |
Defining an analytic framework to evaluate quantitative MRI markers of traumatic axonal injury: preliminary results in a mouse closed head injury model M Haber, EB Hutchinson, N Sadeghi, WH Cheng, D Namjoshi, P Cripton, ... eneuro 4 (5), 2017 | 38 | 2017 |
Repetitive closed-head impact model of engineered rotational acceleration (CHIMERA) injury in rats increases impulsivity, decreases dopaminergic innervation in the olfactory … CV Haar, KM Martens, A Bashir, KA McInnes, WH Cheng, H Cheung, ... Experimental neurology 317, 87-99, 2019 | 31 | 2019 |
Development of vitamin C irrigation saline to promote graft healing in anterior cruciate ligament reconstruction SC Fu, WH Cheng, YC Cheuk, TY Mok, C Rolf, SH Yung, KM Chan Journal of Orthopaedic Translation 1 (1), 67-77, 2013 | 28 | 2013 |
An end-to-end system for automatic characterization of iba1 immunopositive microglia in whole slide imaging AD Kyriazis, S Noroozizadeh, A Refaee, W Choi, LT Chu, A Bashir, ... Neuroinformatics 17, 373-389, 2019 | 24 | 2019 |
Development of a novel, sensitive translational immunoassay to detect plasma glial fibrillary acidic protein (GFAP) after murine traumatic brain injury EB Button, WH Cheng, C Barron, H Cheung, A Bashir, J Cooper, J Gill, ... Alzheimer's Research & Therapy 13, 1-27, 2021 | 15 | 2021 |
High-density lipoproteins at the interface between central nervous system and plasma lipoprotein metabolism J Robert, WH Cheng, A Hayat, T Ward-Able, CL Wellington Clinical Lipidology and Metabolic Disorders 10 (1), 69, 2015 | 4 | 2015 |
The 3rd joint symposium of the international and national neurotrauma societies and AANS/CNS Section on neurotrauma and critical care august 11-16, 2018 Toronto, Canada JR Huie J Neurotrauma 35, A-154, 2018 | 3 | 2018 |