| In vivo prime editing of a metabolic liver disease in mice D Böck, T Rothgangl, L Villiger, L Schmidheini, M Matsushita, N Mathis, ... Science translational medicine 14 (636), eabl9238, 2022 | 127 | 2022 |
| Predicting prime editing efficiency and product purity by deep learning N Mathis, A Allam, L Kissling, KF Marquart, L Schmidheini, C Solari, ... Nature biotechnology 41 (8), 1151-1159, 2023 | 76 | 2023 |
| Dark-field microwells toward high-throughput direct miRNA sensing with gold nanoparticles S Hwu, Y Blickenstorfer, RF Tiefenauer, C Gonnelli, L Schmidheini, ... ACS sensors 4 (7), 1950-1956, 2019 | 27 | 2019 |
| Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibility L Schmidheini, N Mathis, KF Marquart, T Rothgangl, L Kissling, D Böck, ... Nature Chemical Biology 20 (3), 333-343, 2024 | 18 | 2024 |
| Replacing the SpCas9 HNH domain by deaminases generates compact base editors with an alternative targeting scope L Villiger, L Schmidheini, N Mathis, T Rothgangl, K Marquart, G Schwank Molecular Therapy-Nucleic Acids 26, 502-510, 2021 | 13 | 2021 |
| Machine learning prediction of prime editing efficiency across diverse chromatin contexts N Mathis, A Allam, A Tálas, L Kissling, E Benvenuto, L Schmidheini, ... Nature Biotechnology, 1-8, 2024 | 9 | 2024 |
| Self-assembly of nanodiamonds and plasmonic nanoparticles for nanoscopy L Schmidheini, RF Tiefenauer, V Gatterdam, A Frutiger, T Sannomiya, ... Biosensors 12 (3), 148, 2022 | 7 | 2022 |
| Treatment of a metabolic liver disease by in vivo prime editing in mice D Böck, T Rothgangl, L Villiger, L Schmidheini, N Mathis, E Ioannidi, ... biorxiv, 2021.08. 17.456632, 2021 | 6 | 2021 |
| Theoretical and experimental investigation of ligand-induced particle–particle interactions S Hwu, Y Blickenstorfer, SJ Ihle, M Garzuel, C Forró, L Schmidheini, ... The Journal of Physical Chemistry C 124 (2), 1566-1574, 2019 | 5 | 2019 |
| Effective genome editing with an enhanced ISDra2 TnpB system and deep learning-predicted ωRNAs KF Marquart, N Mathis, A Mollaysa, S Müller, L Kissling, T Rothgangl, ... Nature Methods, 1-10, 2024 | 2 | 2024 |
| Prime editing of the β1 adrenoceptor in the brain reprograms mouse behavior D Böck, L Tidecks, M Wilhelm, Y Weber, E Ioannidi, J Mumenthaler, ... BioRxiv, 2023.05. 19.541410, 2023 | 2 | 2023 |
| Predicting prime editing efficiency across diverse edit types and chromatin contexts with machine learning N Mathis, A Allam, A Tálas, E Benvenuto, R Schep, T Damodharan, ... bioRxiv, 2023.10. 09.561414, 2023 | 2 | 2023 |
| Treatment of a genetic liver disease in mice through transient prime editor expression T Rothgangl, EI Ioannidi, Y Weber, A Talas, D Boeck, M Matsushita, ... bioRxiv, 2024.01. 22.575834, 2024 | 1 | 2024 |
| Evolving E3 ligase towards recognising novel substrates for targeted protein degradation NS Allet, KB Villi, J Bast, M Bohl, GC Arriaga, PJ Adolff, S Melkonyan, ... | | |
