Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine LT Geller, M Barzily-Rokni, T Danino, OH Jonas, N Shental, D Nejman, ... Science 357 (6356), 1156-1160, 2017 | 1386 | 2017 |
Selective killing of cancer cells by a small molecule targeting the stress response to ROS L Raj, T Ide, AU Gurkar, M Foley, M Schenone, X Li, NJ Tolliday, ... Nature 475 (7355), 231-234, 2011 | 1175 | 2011 |
Cross-regulation between Notch and p63 in keratinocyte commitment to differentiation BC Nguyen, K Lefort, A Mandinova, D Antonini, V Devgan, G Della Gatta, ... Genes & development 20 (8), 1028-1042, 2006 | 478 | 2006 |
Increased Wnt signaling triggers oncogenic conversion of human breast epithelial cells by a Notch-dependent mechanism A Ayyanan, G Civenni, L Ciarloni, C Morel, N Mueller, K Lefort, ... Proceedings of the National Academy of Sciences 103 (10), 3799-3804, 2006 | 432 | 2006 |
Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKα kinases K Lefort, A Mandinova, P Ostano, V Kolev, V Calpini, I Kolfschoten, ... Genes & development 21 (5), 562-577, 2007 | 383 | 2007 |
A small molecule that binds Hedgehog and blocks its signaling in human cells BZ Stanton, LF Peng, N Maloof, K Nakai, X Wang, JL Duffner, KM Taveras, ... Nature chemical biology 5 (3), 154-156, 2009 | 373 | 2009 |
Emerging roles of p53 and other tumour-suppressor genes in immune regulation C Muñoz-Fontela, A Mandinova, SA Aaronson, SW Lee Nature Reviews Immunology 16 (12), 741-750, 2016 | 337 | 2016 |
The non-classical export routes: FGF1 and IL-1α point the way I Prudovsky, A Mandinova, R Soldi, C Bagala, I Graziani, M Landriscina, ... Journal of cell science 116 (24), 4871-4881, 2003 | 239 | 2003 |
EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer V Kolev, A Mandinova, J Guinea-Viniegra, B Hu, K Lefort, C Lambertini, ... Nature cell biology 10 (8), 902-911, 2008 | 237 | 2008 |
Control of signaling-mediated clearance of apoptotic cells by the tumor suppressor p53 KW Yoon, S Byun, E Kwon, SY Hwang, K Chu, M Hiraki, SH Jo, A Weins, ... Science 349 (6247), 1261669, 2015 | 228 | 2015 |
Distinct subcellular localization of calcium binding S100 proteins in human smooth muscle cells and their relocation in response to rises in intracellular calcium A Mandinova, D Atar, BW Schäfer, M Spiess, U Aebi, CW Heizmann Journal of cell science 111 (14), 2043-2054, 1998 | 203 | 1998 |
Identification of ROCK1 kinase as a critical regulator of Beclin1-mediated autophagy during metabolic stress AU Gurkar, K Chu, L Raj, R Bouley, SH Lee, YB Kim, SE Dunn, ... Nature communications 4 (1), 1-13, 2013 | 176 | 2013 |
Copper induces the assembly of a multiprotein aggregate implicated in the release of fibroblast growth factor 1 in response to stress M Landriscina, C Bagalá, A Mandinova, R Soldi, I Micucci, S Bellum, ... Journal of Biological Chemistry 276 (27), 25549-25557, 2001 | 158 | 2001 |
Discovery of a potent and selective DDR1 receptor tyrosine kinase inhibitor HG Kim, L Tan, EL Weisberg, F Liu, P Canning, HG Choi, SA Ezell, H Wu, ... ACS chemical biology 8 (10), 2145-2150, 2013 | 154 | 2013 |
Copper chelation represses the vascular response to injury L Mandinov, A Mandinova, S Kyurkchiev, D Kyurkchiev, I Kehayov, ... Proceedings of the National Academy of Sciences 100 (11), 6700-6705, 2003 | 153 | 2003 |
The p53 pathway as a target in cancer therapeutics: obstacles and promise A Mandinova, SW Lee Science translational medicine 3 (64), 64rv1-64rv1, 2011 | 135 | 2011 |
The intracellular translocation of the components of the fibroblast growth factor 1 release complex precedes their assembly prior to export I Prudovsky, C Bagala, F Tarantini, A Mandinova, R Soldi, S Bellum, ... The Journal of cell biology 158 (2), 201, 2002 | 127 | 2002 |
Direct targeting of β-catenin by a small molecule stimulates proteasomal degradation and suppresses oncogenic Wnt/β-catenin signaling SY Hwang, X Deng, S Byun, C Lee, SJ Lee, H Suh, J Zhang, Q Kang, ... Cell reports 16 (1), 28-36, 2016 | 123 | 2016 |
DDR1 receptor tyrosine kinase promotes prosurvival pathway through Notch1 activation HG Kim, SY Hwang, SA Aaronson, A Mandinova, SW Lee Journal of Biological Chemistry 286 (20), 17672-17681, 2011 | 119 | 2011 |
S100A13 mediates the copper-dependent stress-induced release of IL-1α from both human U937 and murine NIH 3T3 cells A Mandinova, R Soldi, I Graziani, C Bagalá, S Bellum, M Landriscina, ... Journal of cell science 116 (13), 2687-2696, 2003 | 115 | 2003 |