| Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor … HD Lim, RM van Rijn, P Ling, RA Bakker, RL Thurmond, R Leurs Journal of Pharmacology and Experimental Therapeutics 314 (3), 1310-1321, 2005 | 358 | 2005 |
| Qualitative determination of false‐positive effects in the acetylcholinesterase assay using thin layer chromatography IK Rhee, RM van Rijn, R Verpoorte Phytochemical Analysis: An International Journal of Plant Chemical and …, 2003 | 215 | 2003 |
| Synthesis and structure–activity relationships of indole and benzimidazole piperazines as histamine H4 receptor antagonists N Terzioglu, RM van Rijn, RA Bakker, IJP De Esch, R Leurs Bioorganic & medicinal chemistry letters 14 (21), 5251-5256, 2004 | 153 | 2004 |
| Opioid-receptor-heteromer-specific trafficking and pharmacology RM van Rijn, JL Whistler, M Waldhoer Current opinion in pharmacology 10 (1), 73-79, 2010 | 115 | 2010 |
| The δ1 opioid receptor is a heterodimer that opposes the actions of the δ2 receptor on alcohol intake RM van Rijn, JL Whistler Biological psychiatry 66 (8), 777-784, 2009 | 107 | 2009 |
| A review of the therapeutic potential of recently developed G protein-biased kappa agonists KL Mores, BR Cummins, RJ Cassell, RM van Rijn Frontiers in pharmacology 10, 407, 2019 | 106 | 2019 |
| An integrated perspective on diabetic, alcoholic, and drug-induced neuropathy, etiology, and treatment in the US L Zeng, D Alongkronrusmee, RM van Rijn Journal of pain research, 219-228, 2017 | 103 | 2017 |
| Selection of DNA-encoded libraries to protein targets within and on living cells B Cai, D Kim, S Akhand, Y Sun, RJ Cassell, A Alpsoy, EC Dykhuizen, ... Journal of the American Chemical Society 141 (43), 17057-17061, 2019 | 98 | 2019 |
| Discovery of naturally occurring splice variants of the rat histamine H3 receptor that act as dominant-negative isoforms RA Bakker, AF Lozada, A van Marle, FC Shenton, G Drutel, K Karlstedt, ... Molecular pharmacology 69 (4), 1194-1206, 2006 | 88 | 2006 |
| Oligomerization of recombinant and endogenously expressed human histamine H4 receptors RM Van Rijn, PL Chazot, FC Shenton, K Sansuk, RA Bakker, R Leurs Molecular pharmacology 70 (2), 604-615, 2006 | 80 | 2006 |
| Dual efficacy of delta opioid receptor-selective ligands for ethanol drinking and anxiety RM van Rijn, DI Brissett, JL Whistler Journal of pharmacology and experimental therapeutics 335 (1), 133-139, 2010 | 74 | 2010 |
| Cloning and characterization of dominant negative splice variants of the human histamine H4 receptor RM van Rijn, A van Marle, PL Chazot, E Langemeijer, Y Qin, FC Shenton, ... Biochemical Journal 414 (1), 121-131, 2008 | 74 | 2008 |
| β‐Arrestin 2 dependence of δ opioid receptor agonists is correlated with alcohol intake T Chiang, K Sansuk, RM Van Rijn British journal of pharmacology 173 (2), 332-343, 2016 | 67 | 2016 |
| G protein‐biased kratom‐alkaloids and synthetic carfentanil‐amide opioids as potential treatments for alcohol use disorder AM Gutridge, MT Robins, RJ Cassell, R Uprety, KL Mores, MJ Ko, ... British journal of pharmacology 177 (7), 1497-1513, 2020 | 63 | 2020 |
| Identification of a selective small-molecule inhibitor of type 1 adenylyl cyclase activity with analgesic properties TF Brust, D Alongkronrusmee, M Soto-Velasquez, TA Baldwin, Z Ye, ... Science signaling 10 (467), eaah5381, 2017 | 61 | 2017 |
| Emergence of functional spinal delta opioid receptors after chronic ethanol exposure RM van Rijn, DI Brissett, JL Whistler Biological psychiatry 71 (3), 232-238, 2012 | 60 | 2012 |
| Pharmacological traits of delta opioid receptors: pitfalls or opportunities? RM Van Rijn, JN DeFriel, JL Whistler Psychopharmacology 228, 1-18, 2013 | 59 | 2013 |
| Methadone antinociception is dependent on peripheral opioid receptors L He, J Kim, C Ou, W McFadden, RM van Rijn, JL Whistler The Journal of Pain 10 (4), 369-379, 2009 | 49 | 2009 |
| A novel mitragynine analog with low-efficacy mu opioid receptor agonism displays antinociception with attenuated adverse effects S Chakraborty, JF DiBerto, A Faouzi, SM Bernhard, AM Gutridge, ... Journal of medicinal chemistry 64 (18), 13873-13892, 2021 | 47 | 2021 |
| Commonly used anesthesia/euthanasia methods for brain collection differentially impact MAPK activity in male and female C57BL/6 mice MJ Ko, GE Mulia, RM Van Rijn Frontiers in cellular neuroscience 13, 96, 2019 | 41 | 2019 |
