CD8+ T-cell responses to different HIV proteins have discordant associations with viral load P Kiepiela, K Ngumbela, C Thobakgale, D Ramduth, I Honeyborne, ... Nature medicine 13 (1), 46-53, 2007 | 1243 | 2007 |
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA P Kiepiela, AJ Leslie, I Honeyborne, D Ramduth, C Thobakgale, S Chetty, ... Nature 432 (7018), 769-775, 2004 | 1011 | 2004 |
Fitness cost of escape mutations in p24 Gag in association with control of human immunodeficiency virus type 1 J Martinez-Picado, JG Prado, EE Fry, K Pfafferott, A Leslie, S Chetty, ... Journal of virology 80 (7), 3617-3623, 2006 | 553 | 2006 |
Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA A Leslie, D Kavanagh, I Honeyborne, K Pfafferott, C Edwards, T Pillay, ... The Journal of experimental medicine 201 (6), 891, 2005 | 290 | 2005 |
Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection M Muenchhoff, E Adland, O Karimanzira, C Crowther, M Pace, A Csala, ... Science translational medicine 8 (358), 358ra125-358ra125, 2016 | 132 | 2016 |
High frequency of rapid immunological progression in African infants infected in the era of perinatal HIV prophylaxis W Mphatswe, N Blanckenberg, G Tudor-Williams, A Prendergast, ... Aids 21 (10), 1253-1261, 2007 | 128 | 2007 |
Early virological suppression with three-class antiretroviral therapy in HIV-infected African infants A Prendergast, W Mphatswe, G Tudor-Williams, M Rakgotho, V Pillay, ... Aids 22 (11), 1333-1343, 2008 | 106 | 2008 |
Targeting of a CD8 T cell env epitope presented by HLA-B* 5802 is associated with markers of HIV disease progression and lack of selection pressure KC Ngumbela, CL Day, Z Mncube, K Nair, D Ramduth, C Thobakgale, ... AIDS research and human retroviruses 24 (1), 72-82, 2008 | 87 | 2008 |
Neutrophil counts in persons of African origin CF Thobakgale, T Ndung’u Current opinion in hematology 21 (1), 50-57, 2014 | 84 | 2014 |
Selection of an HLA-C* 03: 04-restricted HIV-1 p24 gag sequence variant is associated with viral escape from KIR2DL3+ natural killer cells: data from an observational cohort in … A Hölzemer, CF Thobakgale, CA Jimenez Cruz, WF Garcia-Beltran, ... PLoS medicine 12 (11), e1001900, 2015 | 82 | 2015 |
Human Immunodeficiency Virus-Specific CD8+ T-Cell Activity Is Detectable from Birth in the Majority of In Utero-Infected Infants CF Thobakgale, D Ramduth, S Reddy, N Mkhwanazi, C de Pierres, ... Journal of virology 81 (23), 12775-12784, 2007 | 77 | 2007 |
Discordant impact of HLA on viral replicative capacity and disease progression in pediatric and adult HIV infection E Adland, P Paioni, C Thobakgale, L Laker, L Mori, M Muenchhoff, ... PLoS pathogens 11 (6), e1004954, 2015 | 65 | 2015 |
Impact of HLA in mother and child on disease progression of pediatric human immunodeficiency virus type 1 infection CF Thobakgale, A Prendergast, H Crawford, N Mkhwanazi, D Ramduth, ... Journal of virology 83 (19), 10234-10244, 2009 | 62 | 2009 |
Immunodominant HIV-1 Cd4+ T cell epitopes in chronic untreated clade C HIV-1 infection D Ramduth, CL Day, CF Thobakgale, NP Mkhwanazi, C de Pierres, ... PLoS One 4 (4), e5013, 2009 | 54 | 2009 |
Replicative capacity of human immunodeficiency virus type 1 transmitted from mother to child is associated with pediatric disease progression rate JG Prado, A Prendergast, C Thobakgale, C Molina, G Tudor-Williams, ... Journal of virology 84 (1), 492-502, 2010 | 43 | 2010 |
CD8+ T Cell Breadth and Ex Vivo Virus Inhibition Capacity Distinguish between Viremic Controllers with and without Protective HLA Class I Alleles CK Koofhethile, ZM Ndhlovu, C Thobakgale-Tshabalala, JG Prado, ... Journal of virology 90 (15), 6818-6831, 2016 | 35 | 2016 |
Frequent and strong antibody-mediated natural killer cell activation in response to HIV-1 Env in individuals with chronic HIV-1 infection CF Thobakgale, L Fadda, K Lane, I Toth, F Pereyra, S Bazner, T Ndung'u, ... Journal of virology 86 (12), 6986-6993, 2012 | 32 | 2012 |
Role of HIV-specific CD8+ T cells in pediatric HIV cure strategies after widespread early viral escape EM Leitman, CF Thobakgale, E Adland, MA Ansari, J Raghwani, ... The Journal of Experimental Medicine 214 (11), 3239, 2017 | 31 | 2017 |
Reduced Expression of Siglec-7, NKG2A, and CD57 on Terminally Differentiated CD56−CD16+ Natural Killer Cell Subset Is Associated with Natural Killer Cell … MZ Zulu, KK Naidoo, Z Mncube, M Jaggernath, PJR Goulder, T Ndung'u, ... AIDS research and human retroviruses 33 (12), 1205-1213, 2017 | 27 | 2017 |
CD8+ T Cell Polyfunctionality Profiles in Progressive and Nonprogressive Pediatric HIV Type 1 Infection CF Thobakgale, H Streeck, N Mkhwanazi, Z Mncube, L Maphumulo, ... AIDS research and human retroviruses 27 (9), 1005-1012, 2011 | 26 | 2011 |