Interruption of lactate uptake by inhibiting mitochondrial pyruvate transport unravels direct antitumor and radiosensitizing effects C Corbet, E Bastien, N Draoui, B Doix, L Mignion, BF Jordan, A Marchand, ... Nature communications 9 (1), 1208, 2018 | 161 | 2018 |
Phase II study of figitumumab in patients with recurrent and/or metastatic squamous cell carcinoma of the head and neck: clinical activity and molecular response (GORTEC 2008-02) S Schmitz, MC Kaminsky-Forrett, S Henry, S Zanetta, L Geoffrois, ... Annals of oncology 23 (8), 2153-2161, 2012 | 90 | 2012 |
Hypoxia imaging with the nitroimidazole 18F-FAZA PET tracer: a comparison with OxyLite, EPR oximetry and 19F-MRI relaxometry A Bol, D Labar, B Jordan, J Magat, L Mignion, V Grégoire, B Gallez Radiotherapy and Oncology 105 (1), 29-35, 2012 | 79 | 2012 |
Hexafluorobenzene in comparison with perfluoro‐15‐crown‐5‐ether for repeated monitoring of oxygenation using 19F MRI in a mouse model L Mignion, J Magat, O Schakman, E Marbaix, B Gallez, BF Jordan Magnetic Resonance in Medicine 69 (1), 248-254, 2013 | 63 | 2013 |
Mapping of oxygen by imaging lipids relaxation enhancement: a potential sensitive endogenous MRI contrast to map variations in tissue oxygenation BF Jordan, J Magat, F Colliez, E Ozel, AC Fruytier, V Marchand, L Mignion, ... Magnetic Resonance in Medicine 70 (3), 732-744, 2013 | 61 | 2013 |
Monitoring Chemotherapeutic Response by Hyperpolarized 13C-Fumarate MRS and Diffusion MRI L Mignion, P Dutta, GV Martinez, P Foroutan, RJ Gillies, BF Jordan Cancer research 74 (3), 686-694, 2014 | 52 | 2014 |
Targeting the bicarbonate transporter SLC4A4 overcomes immunosuppression and immunotherapy resistance in pancreatic cancer F Cappellesso, MP Orban, N Shirgaonkar, E Berardi, J Serneels, ... Nature Cancer 3 (12), 1464-1483, 2022 | 46 | 2022 |
Metformin improves cancer immunotherapy by directly rescuing tumor-infiltrating CD8 T lymphocytes from hypoxia-induced immunosuppression V Finisguerra, T Dvorakova, M Formenti, P Van Meerbeeck, L Mignion, ... Journal for immunotherapy of cancer 11 (5), 2023 | 25 | 2023 |
Tumor reoxygenation following administration of mitogen-activated protein kinase inhibitors: a rationale for combination with radiation therapy O Karroum, J Kengen, P Danhier, J Magat, L Mignion, C Bouzin, J Verrax, ... Radiotherapy and Oncology 105 (1), 64-71, 2012 | 23 | 2012 |
Obesity and triple‐negative‐breast‐cancer: Is apelin a new key target? F Gourgue, L Mignion, M Van Hul, N Dehaen, E Bastien, V Payen, ... Journal of cellular and molecular medicine 24 (17), 10233-10244, 2020 | 21 | 2020 |
Non‐invasive in vivo imaging of early metabolic tumor response to therapies targeting choline metabolism L Mignion, P Danhier, J Magat, PE Porporato, J Masquelier, V Gregoire, ... International Journal of Cancer 138 (8), 2043-2049, 2016 | 20 | 2016 |
Multimodal imaging of tumor response to sorafenib combined with radiation therapy: comparison between diffusion‐weighted MRI, choline spectroscopy and 18F … O Karroum, L Mignion, J Kengen, L Karmani, P Levêque, P Danhier, ... Contrast media & molecular imaging 8 (3), 274-280, 2013 | 18 | 2013 |
Evaluation of syrosingopine, an MCT inhibitor, as potential modulator of tumor metabolism and extracellular acidification C Buyse, N Joudiou, A Warscotte, E Richiardone, L Mignion, C Corbet, ... Metabolites 12 (6), 557, 2022 | 17 | 2022 |
Influence of paramagnetic melanin on the MRI contrast in melanoma: a combined high‐field (11.7 T) MRI and EPR study Q Godechal, L Mignion, O Karroum, J Magat, P Danhier, R Morandini, ... Contrast media & molecular imaging 9 (2), 154-160, 2014 | 17 | 2014 |
Application of MOBILE (Mapping of Oxygen By Imaging Lipids relaxation Enhancement) to Study Variations in Tumor Oxygenation BF Jordan, J Magat, F Colliez, E Ozel, AC Fruytier, V Marchand, L Mignion, ... Oxygen Transport to Tissue XXXV, 281-288, 2013 | 15 | 2013 |
Impact of inhibition of the mitochondrial pyruvate carrier on the tumor extracellular pH as measured by CEST-MRI C Buyse, N Joudiou, C Corbet, O Feron, L Mignion, J Flament, B Gallez Cancers 13 (17), 4278, 2021 | 14 | 2021 |
Metabolic imaging using hyperpolarized 13C‐pyruvate to assess sensitivity to the B‐Raf inhibitor vemurafenib in melanoma cells and xenografts S Acciardo, L Mignion, E Lacomblez, C Schoonjans, N Joudiou, ... Journal of cellular and molecular medicine 24 (2), 1934-1944, 2020 | 13 | 2020 |
Metabolic Imaging Using Hyperpolarized Pyruvate–Lactate Exchange Assesses Response or Resistance to the EGFR Inhibitor Cetuximab in Patient-Derived HNSCC Xenografts L Mignion, S Acciardo, F Gourgue, N Joudiou, X Caignet, RM Goebbels, ... Clinical Cancer Research 26 (8), 1932-1943, 2020 | 12 | 2020 |
Biomarkers of tumour redox status in response to modulations of glutathione and thioredoxin antioxidant pathways J Kengen, JP Deglasse, MA Neveu, L Mignion, C Desmet, F Gourgue, ... Free Radical Research 52 (2), 256-266, 2018 | 11 | 2018 |
Noninvasive detection of the endogenous free radical melanin in human skin melanomas using electron paramagnetic resonance (EPR) L Mignion, CM Desmet, E Harkemanne, I Tromme, N Joudiou, M Wehbi, ... Free Radical Biology and Medicine 190, 226-233, 2022 | 10 | 2022 |