Feedback between p21 and reactive oxygen production is necessary for cell senescence JF Passos, G Nelson, C Wang, T Richter, C Simillion, CJ Proctor, S Miwa, ... Molecular systems biology 6 (1), 347, 2010 | 1006 | 2010 |
Oxidative changes and signalling pathways are pivotal in initiating age-related changes in articular cartilage W Hui, DA Young, AD Rowan, X Xu, TE Cawston, CJ Proctor Annals of the rheumatic diseases, annrheumdis-2014-206295, 2015 | 169 | 2015 |
Explaining oscillations and variability in the p53-Mdm2 system CJ Proctor, DA Gray BMC systems biology 2 (1), 75, 2008 | 139 | 2008 |
Towards an e-biology of ageing: integrating theory and data TBL Kirkwood, RJ Boys, CS Gillespie, CJ Proctor, DP Shanley, ... Nature Reviews Molecular Cell Biology 4 (3), 243, 2003 | 137 | 2003 |
Modelling the molecular mechanisms of aging MT Mc Auley, AM Guimera, D Hodgson, N Mcdonald, KM Mooney, ... Bioscience reports 37 (1), BSR20160177, 2017 | 123 | 2017 |
Modelling telomere shortening and the role of oxidative stress CJ Proctor, TBL Kirkwood Mechanisms of ageing and development 123 (4), 351-363, 2002 | 117 | 2002 |
Modelling the actions of chaperones and their role in ageing CJ Proctor, C Sőti, RJ Boys, CS Gillespie, DP Shanley, DJ Wilkinson, ... Mechanisms of ageing and development 126 (1), 119-131, 2005 | 103 | 2005 |
GSK3 and p53-is there a link in Alzheimer's disease? CJ Proctor, DA Gray Molecular neurodegeneration 5 (1), 7, 2010 | 93 | 2010 |
Age-related changes in mesenchymal stem cells identified using a multi-omics approach MJ Peffers, J Collins, Y Fang, K Goljanek-Whysall, M Rushton, J Loughlin, ... Eur Cell Mater 31 (136), e59, 2016 | 75 | 2016 |
Modelling the role of the Hsp70/Hsp90 system in the maintenance of protein homeostasis CJ Proctor, IAJ Lorimer PLoS One 6 (7), e22038, 2011 | 72 | 2011 |
Modelling antipredator vigilance and flight response in group foragers when warning signals are ambiguous CJ Proctor, M Broom, GD Ruxton Journal of Theoretical Biology 211 (4), 409-417, 2001 | 57 | 2001 |
A mathematical model of ageing in yeast CS Gillespie, CJ Proctor, RJ Boys, DP Shanley, DJ Wilkinson, ... Journal of theoretical biology 229 (2), 189-196, 2004 | 54 | 2004 |
Tools for the SBML Community CS Gillespie, DJ Wilkinson, CJ Proctor, DP Shanley, RJ Boys, ... Bioinformatics 22 (5), 628-629, 2006 | 49 | 2006 |
Modelling cellular senescence as a result of telomere state CJ Proctor, TBL Kirkwood Aging cell 2 (3), 151-157, 2003 | 46 | 2003 |
An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline CJ Proctor, M Tsirigotis, DA Gray BMC systems biology 1 (1), 17, 2007 | 44 | 2007 |
Somatic mutations and ageing in silico TBL Kirkwood, CJ Proctor Mechanisms of ageing and development 124 (1), 85-92, 2003 | 39 | 2003 |
Investigating interventions in Alzheimer's disease with computer simulation models CJ Proctor, D Boche, DA Gray, JAR Nicoll PloS one 8 (9), e73631, 2013 | 37 | 2013 |
Modelling the role of UCH-L1 on protein aggregation in age-related neurodegeneration CJ Proctor, PJ Tangeman, HC Ardley PLoS One 5 (10), e13175, 2010 | 35 | 2010 |
Nutrition research and the impact of computational systems biology MT Mc Auley, CJ Proctor, BM Corfe, GJ Cuskelly, KM Mooney J Comput Sci Syst Biol 6: 271-285. 6 (5), 271-285, 2013 | 34 | 2013 |
The role of intracellular peroxide levels on the development and maintenance of telomere-dependent senescence T Richter, C Proctor Experimental gerontology 42 (11), 1043-1052, 2007 | 34 | 2007 |