Copper-facilitated Suzuki reactions: Application to 2-heterocyclic boronates JZ Deng, DV Paone, AT Ginnetti, H Kurihara, SD Dreher, SA Weissman, ... Organic Letters 11 (2), 345-347, 2009 | 235 | 2009 |
Potent, Orally Bioavailable Calcitonin Gene-Related Peptide Receptor Antagonists for the Treatment of Migraine: Discovery of N-[(3R,6S)-6-(2,3-Difluorophenyl)-2-oxo-1- (2,2,2 … DV Paone, AW Shaw, DN Nguyen, CS Burgey, JZ Deng, SA Kane, ... Journal of medicinal chemistry 50 (23), 5564-5567, 2007 | 164 | 2007 |
Reduction of Aflatoxin B1 Dialdehyde by Rat and Human Aldo-keto Reductases FP Guengerich, H Cai, M McMahon, JD Hayes, TR Sutter, JD Groopman, ... Chemical research in toxicology 14 (6), 727-737, 2001 | 96 | 2001 |
An Intercalated and Thermally Stable FAPY Adduct of Aflatoxin B1 in a DNA Duplex: Structural Refinement from 1H NMR H Mao, Z Deng, F Wang, TM Harris, MP Stone Biochemistry 37 (13), 4374-4387, 1998 | 85 | 1998 |
Low molecular weight cationic lipids for oligonucleotide delivery JA Bawiec III, ZJ Deng US Patent 9,029,604, 2015 | 82 | 2015 |
Unraveling the aflatoxin− FAPY conundrum: structural basis for differential replicative processing of isomeric forms of the formamidopyrimidine-type DNA adduct of aflatoxin B1 KL Brown, JZ Deng, RS Iyer, LG Iyer, MW Voehler, MP Stone, CM Harris, ... Journal of the American Chemical Society 128 (47), 15188-15199, 2006 | 68 | 2006 |
Synthesis of the (3R,6S)-3-Amino-6-(2,3-difluorophenyl)azepan-2-one of Telcagepant (MK-0974), a Calcitonin Gene-Related Peptide Receptor Antagonist for the … CS Burgey, DV Paone, AW Shaw, JZ Deng, DN Nguyen, CM Potteiger, ... Organic Letters 10 (15), 3235-3238, 2008 | 67 | 2008 |
Imidazopyridine CB2 agonists: optimization of CB2/CB1 selectivity and implications for in vivo analgesic efficacy BW Trotter, KK Nanda, CS Burgey, CM Potteiger, JZ Deng, AI Green, ... Bioorganic & medicinal chemistry letters 21 (8), 2354-2358, 2011 | 64 | 2011 |
Development of an oxazolopyridine series of dual thrombin/factor Xa inhibitors via structure-guided lead optimization JZ Deng, DR McMasters, PMA Rabbat, PD Williams, CA Coburn, Y Yan, ... Bioorganic & medicinal chemistry letters 15 (20), 4411-4416, 2005 | 59 | 2005 |
Benzodiazepine calcitonin gene-related peptide (CGRP) receptor antagonists: optimization of the 4-substituted piperidine CS Burgey, CA Stump, DN Nguyen, JZ Deng, AG Quigley, BR Norton, ... Bioorganic & medicinal chemistry letters 16 (19), 5052-5056, 2006 | 56 | 2006 |
CGRP receptor antagonists CS Burgey, ZJ Deng, DN Nguyen, DV Paone, AW Shaw, TM Williams US Patent 6,953,790, 2005 | 36 | 2005 |
Expanding the scope of the Cu assisted Suzuki–Miyaura reaction BM Crowley, CM Potteiger, JZ Deng, CK Prier, DV Paone, CS Burgey Tetrahedron letters 52 (39), 5055-5059, 2011 | 32 | 2011 |
CGRP receptor antagonists CS Burgey, ZJ Deng, DN Nguyen, DV Paone, AW Shaw, TM Williams US Patent 7,235,545, 2007 | 30 | 2007 |
CGRP receptor antagonists CS Burgey, DV Paone, AW Shaw, DN Nguyen, ZJ Deng, TM Williams, ... US Patent 8,039,460, 2011 | 27 | 2011 |
P2 pyridine N-oxide thrombin inhibitors: a novel peptidomimetic scaffold PG Nantermet, CS Burgey, KA Robinson, JM Pellicore, CL Newton, ... Bioorganic & medicinal chemistry letters 15 (11), 2771-2775, 2005 | 27 | 2005 |
The development of an in vitro assay to screen lipid based nanoparticles for siRNA delivery Y Zhang, L Arrington, D Boardman, J Davis, Y Xu, K DiFelice, S Stirdivant, ... Journal of Controlled Release 174, 7-14, 2014 | 25 | 2014 |
Optimization of azepanone calcitonin gene-related peptide (CGRP) receptor antagonists: development of novel spiropiperidines CS Burgey, CM Potteiger, JZ Deng, SD Mosser, CA Salvatore, S Yu, ... Bioorganic & medicinal chemistry letters 19 (22), 6368-6372, 2009 | 24 | 2009 |
CGRP receptor antagonists CS Burgey, ZJ Deng, DN Nguyen, DV Paone, AW Shaw, TM Williams US Patent 7,534,784, 2009 | 21 | 2009 |
Orally bioavailable imidazoazepanes as calcitonin gene-related peptide (CGRP) receptor antagonists: discovery of MK-2918 DV Paone, DN Nguyen, AW Shaw, CS Burgey, CM Potteiger, JZ Deng, ... Bioorganic & medicinal chemistry letters 21 (9), 2683-2686, 2011 | 18 | 2011 |
A novel and efficient synthesis of 2, 5-substituted 1, 2, 4-triazol-3-ones JZ Deng, CS Burgey Tetrahedron letters 46 (46), 7993-7996, 2005 | 18 | 2005 |