关注
Mohamed W. Attwa
Mohamed W. Attwa
King Saud University, College of Pharmacy, Pharmaceutical Chemistry Department
在 ksu.edu.sa 的电子邮件经过验证
标题
引用次数
引用次数
年份
Isatin-benzoazine molecular hybrids as potential antiproliferative agents: synthesis and in vitro pharmacological profiling
HA Abdel-Aziz, WM Eldehna, AB Keeton, GA Piazza, AA Kadi, MW Attwa, ...
Drug Design, Development and Therapy, 2333-2346, 2017
552017
An LC–MS/MS method for rapid and sensitive high‐throughput simultaneous determination of various protein kinase inhibitors in human plasma
AS Abdelhameed, MW Attwa, AA Kadi
Biomedical Chromatography 31 (2), e3793, 2017
482017
Metabolic stability assessment of new parp inhibitor talazoparib using validated lc–ms/ms methodology: In silico metabolic vulnerability and toxicity studies
MW Attwa, AA Kadi, AS Abdelhameed, HA Alhazmi
Drug design, development and therapy, 783-793, 2020
452020
Detection and characterization of ponatinib reactive metabolites by liquid chromatography tandem mass spectrometry and elucidation of bioactivation pathways
AA Kadi, HW Darwish, MW Attwa, SM Amer
RSC advances 6 (76), 72575-72585, 2016
412016
Reactive intermediates and bioactivation pathways characterization of avitinib by LC–MS/MS: in vitro metabolic investigation
MW Attwa, AA Kadi, AS Abdelhameed
Journal of Pharmaceutical and Biomedical Analysis 164, 659-667, 2019
392019
Investigation of metabolic degradation of new ALK inhibitor: Entrectinib by LC-MS/MS
MW Attwa, HW Darwish, HA Alhazmi, AA Kadi
Clinica Chimica Acta 485, 298-304, 2018
392018
Identification and characterization of in vitro phase I and reactive metabolites of masitinib using a LC-MS/MS method: bioactivation pathway elucidation
SM Amer, AA Kadi, HW Darwish, MW Attwa
RSC advances 7 (8), 4479-4491, 2017
392017
Identification and characterization of in vivo, in vitro and reactive metabolites of vandetanib using LC–ESI–MS/MS
MW Attwa, AA Kadi, HW Darwish, SM Amer, NS Al-Shakliah
Chemistry Central Journal 12, 1-16, 2018
382018
LC–MS/MS reveals the formation of iminium and quinone methide reactive intermediates in entrectinib metabolism: in vivo and in vitro metabolic investigation
MW Attwa, AA Kadi, H Alrabiah, HW Darwish
Journal of pharmaceutical and biomedical analysis 160, 19-30, 2018
362018
Identification and characterization of in silico, in vivo, in vitro, and reactive metabolites of infigratinib using LC-ITMS: Bioactivation pathway elucidation and in silico …
NS Al-Shakliah, MW Attwa, AA Kadi, H AlRabiah
RSC advances 10 (28), 16231-16244, 2020
352020
Development of simultaneous determination of empagliflozin and metformin in human plasma using liquid chromatography–mass spectrometry and application to pharmacokinetics
T Wattamwar, A Mungantiwar, S Halde, N Pandita
European Journal of Mass Spectrometry 26 (2), 117-130, 2020
342020
Liquid chromatography tandem mass spectrometry method for the quantification of vandetanib in human plasma and rat liver microsomes matrices: metabolic stability investigation
SM Amer, AA Kadi, HW Darwish, MW Attwa
Chemistry Central Journal 11, 1-8, 2017
332017
LC-MS/MS reveals the formation of aldehydes and iminium reactive intermediates in foretinib metabolism: phase I metabolic profiling
AA Kadi, SM Amer, HW Darwish, MW Attwa
RSC advances 7 (58), 36279-36287, 2017
332017
Liquid chromatographic-tandem mass spectrometric assay for simultaneous quantitation of tofacitinib, cabozantinib and afatinib in human plasma and urine
MWAAHB Adnan A Kadi , Ali S Abdelhameed, Hany W Darwish
Tropical Journal of Pharmaceutical Research, 2016
332016
Detection and characterization of olmutinib reactive metabolites by LC‐MS/MS: Elucidation of bioactivation pathways
MW Attwa, AA Kadi, AS Abdelhameed
Journal of Separation Science, 2019
322019
A reliable and stable method for the determination of foretinib in human plasma by LC-MS/MS: application to metabolic stability investigation and excretion rate
MW Attwa, AA Kadi, HW Darwish, SM Amer, H Alrabiah
European Journal of Mass Spectrometry 24 (4), 344-351, 2018
322018
A highly efficient and sensitive LC‐MS/MS method for the determination of afatinib in human plasma: application to a metabolic stability study
AA Kadi, AS Abdelhameed, HW Darwish, MW Attwa, NS Al‐Shakliah
Biomedical Chromatography 30 (8), 1248-1255, 2016
322016
Phase I metabolic profiling and unexpected reactive metabolites in human liver microsome incubations of X-376 using LC-MS/MS: bioactivation pathway elucidation and in silico …
MW Attwa, AA Kadi, AS Abdelhameed
RSC advances 10 (9), 5412-5427, 2020
312020
LC–MS/MS method for the quantification of masitinib in RLMs matrix and rat urine: application to metabolic stability and excretion rate
SM Amer, AA Kadi, HW Darwish, MW Attwa
Chemistry Central Journal 11, 1-7, 2017
312017
Investigation of the metabolic stability of olmutinib by validated LC-MS/MS: quantification in human plasma
MW Attwa, AA Kadi, HW Darwish, AS Abdelhameed
RSC advances 8 (70), 40387-40394, 2018
302018
系统目前无法执行此操作,请稍后再试。
文章 1–20