Dickkopf-1 is a master regulator of joint remodeling D Diarra, M Stolina, K Polzer, J Zwerina, MS Ominsky, D Dwyer, A Korb, ... Nature medicine 13 (2), 156-163, 2007 | 1631 | 2007 |
Targeted deletion of the sclerostin gene in mice results in increased bone formation and bone strength X Li, MS Ominsky, QT Niu, N Sun, B Daugherty, D D'Agostin, C Kurahara, ... Journal of Bone and Mineral Research 23 (6), 860-869, 2008 | 1116 | 2008 |
Sclerostin antibody treatment increases bone formation, bone mass, and bone strength in a rat model of postmenopausal osteoporosis X Li, MS Ominsky, KS Warmington, S Morony, J Gong, J Cao, Y Gao, ... Journal of Bone and Mineral Research 24 (4), 578-588, 2009 | 961 | 2009 |
Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia J Li, I Sarosi, RC Cattley, J Pretorius, F Asuncion, M Grisanti, S Morony, ... Bone 39 (4), 754-766, 2006 | 552 | 2006 |
Two doses of sclerostin antibody in cynomolgus monkeys increases bone formation, bone mineral density, and bone strength MS Ominsky, F Vlasseros, J Jolette, SY Smith, B Stouch, G Doellgast, ... Journal of Bone and Mineral Research 25 (5), 948-959, 2010 | 544 | 2010 |
Denosumab, a fully human monoclonal antibody to RANKL, inhibits bone resorption and increases BMD in knock‐in mice that express chimeric (murine/human) RANKL PJ Kostenuik, HQ Nguyen, J McCabe, KS Warmington, C Kurahara, ... Journal of bone and mineral research 24 (2), 182-195, 2009 | 505 | 2009 |
Sclerostin and Dickkopf-1 as therapeutic targets in bone diseases HZ Ke, WG Richards, X Li, MS Ominsky Endocrine reviews 33 (5), 747-783, 2012 | 475 | 2012 |
Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones MS Ominsky, C Li, X Li, HL Tan, E Lee, M Barrero, FJ Asuncion, D Dwyer, ... Journal of Bone and Mineral Research 26 (5), 1012-1021, 2011 | 305 | 2011 |
Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats X Li, KS Warmington, QT Niu, FJ Asuncion, M Barrero, M Grisanti, ... Journal of Bone and Mineral Research 25 (12), 2647-2656, 2010 | 289 | 2010 |
Comparison of effects of the bisphosphonate alendronate versus the RANKL inhibitor denosumab on murine fracture healing LC Gerstenfeld, DJ Sacks, M Pelis, ZD Mason, DT Graves, M Barrero, ... Journal of bone and mineral research 24 (2), 196-208, 2009 | 278 | 2009 |
Effects of denosumab on bone histomorphometry: the FREEDOM and STAND studies IR Reid, PD Miller, JP Brown, DL Kendler, A Fahrleitner‐Pammer, I Valter, ... Journal of Bone and Mineral Research 25 (10), 2256-2265, 2010 | 265 | 2010 |
Neutralisation of Dkk-1 protects from systemic bone loss during inflammation and reduces sclerostin expression GR Heiland, K Zwerina, W Baum, T Kireva, JH Distler, M Grisanti, ... Annals of the rheumatic diseases 69 (12), 2152-2159, 2010 | 258 | 2010 |
A bispecific antibody targeting sclerostin and DKK-1 promotes bone mass accrual and fracture repair M Florio, K Gunasekaran, M Stolina, X Li, L Liu, B Tipton, ... Nature communications 7 (1), 11505, 2016 | 238 | 2016 |
RANKL inhibition with osteoprotegerin increases bone strength by improving cortical and trabecular bone architecture in ovariectomized rats MS Ominsky, X Li, FJ Asuncion, M Barrero, KS Warmington, D Dwyer, ... Journal of Bone and Mineral Research 23 (5), 672-682, 2008 | 169 | 2008 |
Tissue‐level mechanisms responsible for the increase in bone formation and bone volume by sclerostin antibody MS Ominsky, QT Niu, C Li, X Li, HZ Ke Journal of Bone and Mineral Research 29 (6), 1424-1430, 2014 | 159 | 2014 |
Sclerostin antibody improves skeletal parameters in a Brtl/+ mouse model of osteogenesis imperfecta BP Sinder, MM Eddy, MS Ominsky, MS Caird, JC Marini, KM Kozloff Journal of Bone and Mineral Research 28 (1), 73-80, 2013 | 144 | 2013 |
Sclerostin antibody treatment improves bone mass, bone strength, and bone defect regeneration in rats with type 2 diabetes mellitus C Hamann, M Rauner, Y Höhna, R Bernhardt, J Mettelsiefen, C Goettsch, ... Journal of Bone and Mineral Research 28 (3), 627-638, 2013 | 142 | 2013 |
Effects of sclerostin antibodies in animal models of osteoporosis MS Ominsky, RW Boyce, X Li, HZ Ke Bone 96, 63-75, 2017 | 132 | 2017 |
RANKL is a marker and mediator of local and systemic bone loss in two rat models of inflammatory arthritis M Stolina, S Adamu, M Ominsky, D Dwyer, F Asuncion, Z Geng, ... Journal of Bone and Mineral Research 20 (10), 1756-1765, 2005 | 131 | 2005 |
Dickkopf‐1 regulates bone formation in young growing rodents and upon traumatic injury X Li, M Grisanti, W Fan, FJ Asuncion, HL Tan, D Dwyer, CY Han, L Yu, ... Journal of Bone and Mineral Research 26 (11), 2610-2621, 2011 | 130 | 2011 |