Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis NA Scott, A Andrusaite, P Andersen, M Lawson, C Alcon-Giner, C Leclaire, ... Science translational medicine 10 (464), eaao4755, 2018 | 273 | 2018 |
From ingestion to colonization: the influence of the host environment on regulation of the LEE encoded type III secretion system in enterohaemorrhagic Escherichia coli JPR Connolly, BB Finlay, AJ Roe Frontiers in Microbiology 6, 568, 2015 | 77 | 2015 |
The host metabolite D-serine contributes to bacterial niche specificity through gene selection JPR Connolly, RJ Goldstone, K Burgess, RJ Cogdell, SA Beatson, ... The ISME journal 9 (4), 1039-1051, 2015 | 75 | 2015 |
Propionic acid promotes the virulent phenotype of Crohn’s disease-associated adherent-invasive Escherichia coli MJ Ormsby, SA Johnson, N Carpena, LM Meikle, RJ Goldstone, ... Cell reports 30 (7), 2297-2305. e5, 2020 | 69 | 2020 |
A highly conserved bacterial D-serine uptake system links host metabolism and virulence JPR Connolly, M Gabrielsen, RJ Goldstone, R Grinter, D Wang, ... PLoS pathogens 12 (1), e1005359, 2016 | 66 | 2016 |
Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion JPR Connolly, SL Slater, N O’Boyle, RJ Goldstone, VF Crepin, ... Nature Communications 9 (1), 4187, 2018 | 64 | 2018 |
The metabolic enzyme AdhE controls the virulence of Escherichia coli O157:H7 KSH Beckham, JPR Connolly, JM Ritchie, D Wang, JA Gawthorne, ... Molecular microbiology 93 (1), 199-211, 2014 | 59 | 2014 |
Postgenomics Characterization of an Essential Genetic Determinant of Mammary Pathogenic Escherichia coli SE Blum, RJ Goldstone, JPR Connolly, M Répérant-Ferter, P Germon, ... MBio 9 (2), 10.1128/mbio. 00423-18, 2018 | 40 | 2018 |
Control freaks—signals and cues governing the regulation of virulence in attaching and effacing pathogens NCA Turner, JPR Connolly, AJ Roe Biochemical Society Transactions 47 (1), 229-238, 2019 | 33 | 2019 |
Characterization of the mode of action of aurodox, a type III secretion system inhibitor from Streptomyces goldiniensis RE McHugh, N O’Boyle, JPR Connolly, PA Hoskisson, AJ Roe Infection and immunity 87 (2), 10.1128/iai. 00595-18, 2019 | 32 | 2019 |
The Highly Conserved Escherichia coli Transcription Factor YhaJ Regulates Aromatic Compound Degradation N Palevsky, B Shemer, JPR Connolly, S Belkin Frontiers in Microbiology 7, 1490, 2016 | 28 | 2016 |
Genomic and transcriptomic characterization of Pseudomonas aeruginosa small colony variants derived from a chronic infection model S Irvine, B Bunk, HK Bayes, C Spröer, JPR Connolly, A Six, TJ Evans, ... Microbial genomics 5 (4), e000262, 2019 | 25 | 2019 |
Distinct intraspecies virulence mechanisms regulated by a conserved transcription factor JPR Connolly, N O’Boyle, NCA Turner, DF Browning, AJ Roe Proceedings of the National Academy of Sciences 116 (39), 19695-19704, 2019 | 23 | 2019 |
Novel compounds targeting the enterohemorrhagic Escherichia coli type three secretion system reveal insights into mechanisms of secretion inhibition R Zambelloni, JPR Connolly, A Huerta Uribe, K Burgess, R Marquez, ... Molecular Microbiology 105 (4), 606-619, 2017 | 23 | 2017 |
Identification and Characterization of Novel Compounds Blocking Shiga Toxin Expression in Escherichia coli O157:H7 A Huerta-Uribe, ZR Marjenberg, N Yamaguchi, S Fitzgerald, ... Frontiers in microbiology 7, 1930, 2016 | 14 | 2016 |
Intracellular d-Serine Accumulation Promotes Genetic Diversity via Modulated Induction of RecA in Enterohemorrhagic Escherichia coli JPR Connolly, AJ Roe Journal of Bacteriology 198 (24), 3318-3328, 2016 | 12 | 2016 |
Tracking elusive cargo: Illuminating spatio‐temporal Type 3 effector protein dynamics using reporters N O'Boyle, JPR Connolly, AJ Roe Cellular microbiology 20 (1), e12797, 2018 | 10 | 2018 |
When and where? Pathogenic Escherichia coli differentially sense host D-serine using a universal transporter system to monitor their environment JPR Connolly, AJ Roe Microbial cell 3 (4), 181, 2016 | 8 | 2016 |
Genomic inversion drives small colony variant formation and increased virulence in P. aeruginosa S Irvine, B Bunk, HK Bayes, C Sprӧer, JPR Connolly, A Six, TJ Evans, ... bioRxiv, 356386, 2018 | 1 | 2018 |
Author Correction: Host-associated niche metabolism controls enteric infection through fine-tuning the regulation of type 3 secretion JPR Connolly, SL Slater, N O’Boyle, RJ Goldstone, VF Crepin, ... Nature Communications 9, 2018 | | 2018 |