iPSC-derived human microglia-like cells to study neurological diseases EM Abud, RN Ramirez, ES Martinez, LM Healy, CHH Nguyen, ... Neuron 94 (2), 278-293. e9, 2017 | 753 | 2017 |
Microglial control of astrocytes in response to microbial metabolites V Rothhammer, DM Borucki, EC Tjon, MC Takenaka, CC Chao, ... Nature 557 (7707), 724-728, 2018 | 704 | 2018 |
Roles of microglia in brain development, tissue maintenance and repair M Michell-Robinson, H Touil, L Healy, D Owen, B Durafourt, A Bar-Or, ... Brain 138 (5), 1138-1159, 2015 | 380 | 2015 |
Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype K Gabrusiewicz, B Rodriguez, J Wei, Y Hashimoto, LM Healy, SN Maiti, ... JCI insight 1 (2), 2016 | 378 | 2016 |
Control of tumor-associated macrophages and T cells in glioblastoma via AHR and CD39 MC Takenaka, G Gabriely, V Rothhammer, ID Mascanfroni, MA Wheeler, ... Nature neuroscience 22 (5), 729-740, 2019 | 305 | 2019 |
Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes K Gabrusiewicz, X Li, J Wei, Y Hashimoto, AL Marisetty, M Ott, F Wang, ... Oncoimmunology 7 (4), e1412909, 2018 | 246 | 2018 |
Development of a chimeric model to study and manipulate human microglia in vivo J Hasselmann, MA Coburn, W England, DXF Velez, SK Shabestari, ... Neuron 103 (6), 1016-1033. e10, 2019 | 207 | 2019 |
Peripherally derived macrophages modulate microglial function to reduce inflammation after CNS injury AD Greenhalgh, JG Zarruk, LM Healy, SJ Baskar Jesudasan, P Jhelum, ... PLoS biology 16 (10), e2005264, 2018 | 178 | 2018 |
Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans DR Owen, N Narayan, L Wells, L Healy, E Smyth, EA Rabiner, ... Journal of Cerebral Blood Flow & Metabolism 37 (8), 2679-2690, 2017 | 170 | 2017 |
Sphingosine 1-phosphate receptor modulation suppresses pathogenic astrocyte activation and chronic progressive CNS inflammation V Rothhammer, JE Kenison, E Tjon, MC Takenaka, KA de Lima, ... Proceedings of the National Academy of Sciences 114 (8), 2012-2017, 2017 | 162 | 2017 |
MerTK Is a Functional Regulator of Myelin Phagocytosis by Human Myeloid Cells L Healy, SY Perron, Gabrielle, Won, M Michell-Robinson, A Rezk, ... Journal of Immunology 196 (8), 3375-3384, 2016 | 136 | 2016 |
Cytokine-Defined B Cell Responses as Therapeutic Targets in Multiple Sclerosis R Li, A Rezk, L Healy, G Muirhead, A Prat, J Gommerman, A Bar-Or, ... Frontiers in Immunology, 2015 | 105 | 2015 |
Astrocytes have the capacity to act as antigen-presenting cells in the Parkinson’s disease brain J Rostami, G Fotaki, J Sirois, R Mzezewa, J Bergström, M Essand, L Healy, ... Journal of neuroinflammation 17 (1), 1-18, 2020 | 97 | 2020 |
pHERV-W envelope protein fuels microglial cell-dependent damage of myelinated axons in multiple sclerosis D Kremer, J Gruchot, V Weyers, L Oldemeier, P Göttle, L Healy, J Ho Jang, ... Proceedings of the National Academy of Sciences 116 (30), 15216-15225, 2019 | 84 | 2019 |
USP15 regulates type I interferon response and is required for pathogenesis of neuroinflammation S Torre, MJ Polyak, D Langlais, N Fodil, JM Kennedy, I Radovanovic, ... Nature immunology 18 (1), 54-63, 2017 | 84 | 2017 |
Lesion stage-dependent causes for impaired remyelination in MS K Heß, L Starost, NW Kieran, C Thomas, MCJ Vincenten, J Antel, ... Acta neuropathologica 140, 359-375, 2020 | 75 | 2020 |
Effects of fumarates on circulating and CNS myeloid cells in multiple sclerosis M Michell-Robinson, C Moore, L Healy, L Osso, N Zorko, V Grouza, ... Annals of Clinical and Translational Neurology 3 (1), 27-41, 2015 | 70 | 2015 |
Crosstalk between astrocytes and microglia results in increased degradation of α-synuclein and amyloid-β aggregates J Rostami, T Mothes, M Kolahdouzan, O Eriksson, M Moslem, J Bergström, ... Journal of neuroinflammation 18 (1), 1-20, 2021 | 65 | 2021 |
Divergent neuroinflammatory regulation of microglial TREM expression and involvement of NF-κB R Owens, K Grabert, CL Davies, A Alfieri, JP Antel, LM Healy, BW McColl Frontiers in cellular neuroscience 11, 56, 2017 | 64 | 2017 |
Sphingosine 1‐phosphate receptors regulate TLR4‐induced CXCL5 release from astrocytes and microglia SA O'Sullivan, C O'Sullivan, LM Healy, KK Dev, GK Sheridan Journal of Neurochemistry, 2018 | 61 | 2018 |