Endocytic receptors in the renal proximal tubule EI Christensen, H Birn, T Storm, K Weyer, R Nielsen Physiology 27 (4), 223-236, 2012 | 317 | 2012 |
Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin HB BOLDT, MT OVERGAARD, LS LAURSEN, K Weyer, L Sottrup-Jensen, ... Biochemical Journal 358 (2), 359-367, 2001 | 213 | 2001 |
APOE4-mediated amyloid-β pathology depends on its neuronal receptor LRP1 M Tachibana, ML Holm, CC Liu, M Shinohara, T Aikawa, H Oue, ... The Journal of clinical investigation 129 (3), 1272-1277, 2019 | 132 | 2019 |
Cell surface targeting of pregnancy-associated plasma protein A proteolytic activity: reversible adhesion is mediated by two neighboring short consensus repeats LS Laursen, MT Overgaard, K Weyer, HB Boldt, P Ebbesen, ... Journal of Biological Chemistry 277 (49), 47225-47234, 2002 | 127 | 2002 |
Heparan sulfate proteoglycans present PCSK9 to the LDL receptor C Gustafsen, D Olsen, J Vilstrup, S Lund, A Reinhardt, N Wellner, ... Nature communications 8 (1), 503, 2017 | 104 | 2017 |
Megalin-mediated specific uptake of chitosan/siRNA nanoparticles in mouse kidney proximal tubule epithelial cells enables AQP1 gene silencing S Gao, S Hein, F Dagnæs-Hansen, K Weyer, C Yang, R Nielsen, ... Theranostics 4 (10), 1039, 2014 | 104 | 2014 |
Renal uptake of 99mTc-dimercaptosuccinic acid is dependent on normal proximal tubule receptor–mediated endocytosis K Weyer, R Nielsen, SV Petersen, EI Christensen, M Rehling, H Birn Journal of Nuclear Medicine 54 (1), 159-165, 2013 | 85 | 2013 |
The Lin12-notch repeats of pregnancy-associated plasma protein-A bind calcium and determine its proteolytic specificity HB Boldt, K Kjaer-Sorensen, MT Overgaard, K Weyer, CB Poulsen, ... Journal of Biological Chemistry 279 (37), 38525-38531, 2004 | 84 | 2004 |
Mouse model of proximal tubule endocytic dysfunction K Weyer, T Storm, J Shan, S Vainio, R Kozyraki, PJ Verroust, ... Nephrology Dialysis Transplantation 26 (11), 3446-3451, 2011 | 82 | 2011 |
Increased lysosomal proteolysis counteracts protein accumulation in the proximal tubule during focal segmental glomerulosclerosis R Nielsen, G Mollet, EL Esquivel, K Weyer, PK Nielsen, C Antignac, ... Kidney international 84 (5), 902-910, 2013 | 48 | 2013 |
A substrate specificity-determining unit of three Lin12-Notch repeat modules is formed in trans within the pappalysin-1 dimer and requires a sequence stretch C-terminal to the … K Weyer, HB Boldt, CB Poulsen, K Kjaer-Sorensen, C Gyrup, C Oxvig Journal of Biological Chemistry 282 (15), 10988-10999, 2007 | 41 | 2007 |
Distinct functions of megalin and cubilin receptors in recovery of normal and nephrotic levels of filtered albumin Q Ren, K Weyer, Y Rbaibi, KR Long, RJ Tan, R Nielsen, EI Christensen, ... American Journal of Physiology-Renal Physiology 318 (5), F1284-F1294, 2020 | 38 | 2020 |
Abolishment of proximal tubule albumin endocytosis does not affect plasma albumin during nephrotic syndrome in mice K Weyer, PK Andersen, K Schmidt, G Mollet, C Antignac, H Birn, ... Kidney international 93 (2), 335-342, 2018 | 37 | 2018 |
Cell surface adhesion of pregnancy‐associated plasma protein‐A is mediated by four clusters of basic residues located in its third and fourth CCP module K Weyer, MT Overgaard, LS Laursen, CG Nielsen, A Schmitz, ... European journal of biochemistry 271 (8), 1525-1535, 2004 | 37 | 2004 |
Urokinase‐type plasminogen activator contributes to amiloride‐sensitive sodium retention in nephrotic range glomerular proteinuria in mice GR Hinrichs, K Weyer, UG Friis, P Svenningsen, IK Lund, R Nielsen, ... Acta Physiologica 227 (4), e13362, 2019 | 36 | 2019 |
Placental regulation of peptide hormone and growth factor activity by proMBP K Weyer, S Glerup Biology of reproduction 84 (6), 1077-1086, 2011 | 33 | 2011 |
Papp-a2 modulates development of cranial cartilage and angiogenesis in zebrafish embryos K Kjaer-Sorensen, DH Engholm, MR Jepsen, MG Morch, K Weyer, ... Journal of cell science 127 (23), 5027-5037, 2014 | 28 | 2014 |
Generation of urinary albumin fragments does not require proximal tubular uptake K Weyer, R Nielsen, EI Christensen, H Birn Journal of the American Society of Nephrology 23 (4), 591-596, 2012 | 26 | 2012 |
Renin-angiotensin-aldosterone system in the pathogenesis of pregnancy-induced hypertension R Świątkowska-Stodulska, P Kmieć, K Stefańska, K Sworczak Experimental and Clinical Endocrinology & Diabetes 126 (06), 362-366, 2018 | 21 | 2018 |
Megalin dependent urinary cystatin C excretion in ischemic kidney injury in rats D Jensen, C Kierulf-Lassen, MLV Kristensen, R Nørregaard, K Weyer, ... PloS one 12 (6), e0178796, 2017 | 20 | 2017 |