Targeting MET and AXL overcomes resistance to sunitinib therapy in renal cell carcinoma L Zhou, XD Liu, M Sun, X Zhang, P German, S Bai, Z Ding, N Tannir, ... Oncogene 35 (21), 2687-2697, 2016 | 397 | 2016 |
Adiponectin activates AMP-activated protein kinase in muscle cells via APPL1/LKB1-dependent and phospholipase C/Ca2+/Ca2+/calmodulin-dependent protein kinase kinase-dependent … L Zhou, SS Deepa, JC Etzler, J Ryu, X Mao, Q Fang, DD Liu, JM Torres, ... Journal of Biological Chemistry 284 (33), 22426-22435, 2009 | 265 | 2009 |
A disulfide-bond A oxidoreductase-like protein (DsbA-L) regulates adiponectin multimerization M Liu, L Zhou, A Xu, KSL Lam, MD Wetzel, R Xiang, J Zhang, X Xin, ... Proceedings of the National Academy of Sciences 105 (47), 18302-18307, 2008 | 264 | 2008 |
Resveratrol inhibits mTOR signaling by promoting the interaction between mTOR and DEPTOR M Liu, SA Wilk, A Wang, L Zhou, RH Wang, W Ogawa, C Deng, LQ Dong, ... Journal of Biological Chemistry 285 (47), 36387-36394, 2010 | 195 | 2010 |
Resistance to antiangiogenic therapy is associated with an immunosuppressive tumor microenvironment in metastatic renal cell carcinoma XD Liu, A Hoang, L Zhou, S Kalra, A Yetil, M Sun, Z Ding, X Zhang, S Bai, ... Cancer immunology research 3 (9), 1017-1029, 2015 | 192 | 2015 |
Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance L Zhou, J Zhang, Q Fang, M Liu, X Liu, W Jia, LQ Dong, F Liu Molecular pharmacology 76 (3), 596-603, 2009 | 136 | 2009 |
DsbA-L alleviates endoplasmic reticulum stress–induced adiponectin downregulation L Zhou, M Liu, J Zhang, H Chen, LQ Dong, F Liu Diabetes 59 (11), 2809-2816, 2010 | 134 | 2010 |
APPL1 potentiates insulin sensitivity by facilitating the binding of IRS1/2 to the insulin receptor J Ryu, AK Galan, X Xin, F Dong, MA Abdul-Ghani, L Zhou, C Wang, C Li, ... Cell reports 7 (4), 1227-1238, 2014 | 131 | 2014 |
APPL1 mediates adiponectin-stimulated p38 MAPK activation by scaffolding the TAK1-MKK3-p38 MAPK pathway X Xin, L Zhou, CM Reyes, F Liu, LQ Dong American Journal of Physiology-Endocrinology and Metabolism 300 (1), E103-E110, 2011 | 119 | 2011 |
Fat-Specific DsbA-L Overexpression Promotes Adiponectin Multimerization and Protects Mice From Diet-Induced Obesity and Insulin Resistance M Liu, R Xiang, SA Wilk, N Zhang, LB Sloane, K Azarnoush, L Zhou, ... Diabetes, 2012 | 98 | 2012 |
APPL1 mediates adiponectin-induced LKB1 cytosolic localization through the PP2A-PKCζ signaling pathway SS Deepa, L Zhou, J Ryu, C Wang, X Mao, C Li, N Zhang, N Musi, ... Molecular endocrinology 25 (10), 1773-1785, 2011 | 92 | 2011 |
Autophagy mediates HIF2α degradation and suppresses renal tumorigenesis XD Liu, J Yao, DN Tripathi, Z Ding, Y Xu, M Sun, J Zhang, S Bai, ... Oncogene 34 (19), 2450-2460, 2015 | 82 | 2015 |
Autophagy: roles in obesity-induced ER stress and adiponectin downregulation in adipocytes L Zhou, F Liu Autophagy 6 (8), 1196-1197, 2010 | 69 | 2010 |
Disruption of Growth Factor Receptor–Binding Protein 10 in the Pancreas Enhances β-Cell Proliferation and Protects Mice From Streptozotocin-Induced β-Cell Apoptosis J Zhang, N Zhang, M Liu, X Li, L Zhou, W Huang, Z Xu, J Liu, N Musi, ... Diabetes, 2012 | 50 | 2012 |
Fine tuning PDK1 activity by phosphorylation at Ser163 RA Riojas, CK Kikani, C Wang, X Mao, L Zhou, PR Langlais, D Hu, ... Journal of Biological Chemistry 281 (31), 21588-21593, 2006 | 28 | 2006 |
HNF1B loss exacerbates the development of chromophobe renal cell carcinomas M Sun, P Tong, W Kong, B Dong, Y Huang, IY Park, L Zhou, XD Liu, ... Cancer research 77 (19), 5313-5326, 2017 | 27 | 2017 |
Genetic and pharmacological strategies to refunctionalize the von Hippel Lindau R167Q mutant protein Z Ding, P German, S Bai, AS Reddy, XD Liu, M Sun, L Zhou, X Chen, ... Cancer research 74 (11), 3127-3136, 2014 | 26 | 2014 |
Phosphorylation of Adaptor Protein Containing Pleckstrin Homology Domain, Phosphotyrosine Binding Domain and Leucine Zipper Motif 1 (APPL1) at Ser430 Mediates ER stress-induced … M Liu, L Zhou, L Wei, R Villarreal, X Yang, D Hu, RA Riojas, BM Holmes, ... Journal of Biological Chemistry, 2012 | 19 | 2012 |
Phosphorylation-dependent cleavage regulates von Hippel Lindau proteostasis and function P German, S Bai, XD Liu, M Sun, L Zhou, S Kalra, X Zhang, R Minelli, ... Oncogene 35 (38), 4973-4980, 2016 | 13 | 2016 |
Loss of p27 associated with risk for endometrial carcinoma arising in the setting of obesity AS McCampbell, ML Mittelstadt, R Dere, S Kim, L Zhou, B Djordjevic, ... Current molecular medicine 16 (3), 252-265, 2016 | 10 | 2016 |