Depletion of hematogenous macrophages promotes partial hindlimb recovery and neuroanatomical repair after experimental spinal cord injury PG Popovich, Z Guan, P Wei, I Huitinga, N Van Rooijen, BT Stokes Experimental neurology 158 (2), 351-365, 1999 | 844 | 1999 |
Spatial transcriptomics and in situ sequencing to study Alzheimer’s disease WT Chen, A Lu, K Craessaerts, B Pavie, CS Frigerio, N Corthout, X Qian, ... Cell 182 (4), 976-991. e19, 2020 | 598 | 2020 |
Extensive hippocampal demyelination in multiple sclerosis JJG Geurts, L Bö, SD Roosendaal, T Hazes, R Daniëls, F Barkhof, ... Journal of Neuropathology & Experimental Neurology 66 (9), 819-827, 2007 | 351 | 2007 |
Tissue-resident memory T cells populate the human brain J Smolders, KM Heutinck, NL Fransen, EBM Remmerswaal, P Hombrink, ... Nature communications 9 (1), 4593, 2018 | 317 | 2018 |
Progressive multiple sclerosis patients show substantial lesion activity that correlates with clinical disease severity and sex: a retrospective autopsy cohort analysis S Luchetti, NL Fransen, CG van Eden, V Ramaglia, M Mason, I Huitinga Acta neuropathologica 135, 511-528, 2018 | 311 | 2018 |
Gene expression analysis in the human hypothalamus in depression by laser microdissection and real-time PCR: the presence of multiple receptor imbalances SS Wang, W Kamphuis, I Huitinga, JN Zhou, DF Swaab Molecular psychiatry 13 (8), 786-799, 2008 | 286 | 2008 |
The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis J Bauer, I Huitinga, W Zhao, H Lassmann, WF Hickey, CD Dijkstra Glia 15 (4), 437-446, 1995 | 280 | 1995 |
Acute isolation and transcriptome characterization of cortical astrocytes and microglia from young and aged mice M Orre, W Kamphuis, LM Osborn, J Melief, L Kooijman, I Huitinga, ... Neurobiology of aging 35 (1), 1-14, 2014 | 274 | 2014 |
Staining of HLA-DR, Iba1 and CD68 in human microglia reveals partially overlapping expression depending on cellular morphology and pathology DAE Hendrickx, CG van Eden, KG Schuurman, J Hamann, I Huitinga Journal of neuroimmunology 309, 12-22, 2017 | 271 | 2017 |
Transcriptional profiling of human microglia reveals grey–white matter heterogeneity and multiple sclerosis-associated changes M van der Poel, T Ulas, MR Mizee, CC Hsiao, SSM Miedema, null Adelia, ... Nature communications 10 (1), 1139, 2019 | 247 | 2019 |
Expression of interleukin-1 beta in rat dorsal root ganglia J Copray, I Mantingh, N Brouwer, K Biber, BM Küst, RSB Liem, I Huitinga, ... Journal of neuroimmunology 118 (2), 203-211, 2001 | 224 | 2001 |
Distribution of the immune inhibitory molecules CD200 and CD200R in the normal central nervous system and multiple sclerosis lesions suggests neuron-glia and glia-glia interactions N Koning, DF Swaab, RM Hoek, I Huitinga Journal of Neuropathology & Experimental Neurology 68 (2), 159-167, 2009 | 223 | 2009 |
Phagocytic response in photochemically induced infarction of rat cerebral cortex: the role of resident microglia M Schroeter, S Jander, I Huitinga, OW Witte, G Stoll Stroke 28 (2), 382-386, 1997 | 219 | 1997 |
Downregulation of macrophage inhibitory molecules in multiple sclerosis lesions N Koning, L Bö, RM Hoek, I Huitinga Annals of Neurology: Official Journal of the American Neurological …, 2007 | 215 | 2007 |
Complement C 1q‐C 3–associated synaptic changes in multiple sclerosis hippocampus I Michailidou, JGP Willems, EJ Kooi, C van Eden, SM Gold, JJG Geurts, ... Annals of neurology 77 (6), 1007-1026, 2015 | 210 | 2015 |
Epstein Barr virus is not a characteristic feature in the central nervous system in established multiple sclerosis LAN Peferoen, F Lamers, LNR Lodder, WH Gerritsen, I Huitinga, J Melief, ... Brain 133 (5), e137-e137, 2010 | 185 | 2010 |
Effects of antemortem and postmortem variables on human brain mRNA quality: a BrainNet Europe study PF Durrenberger, S Fernando, SN Kashefi, I Ferrer, JJ Hauw, D Seilhean, ... Journal of Neuropathology & Experimental Neurology 69 (1), 70-81, 2010 | 183 | 2010 |
Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis SA Berghoff, L Spieth, T Sun, L Hosang, L Schlaphoff, C Depp, T Düking, ... Nature neuroscience 24 (1), 47-60, 2021 | 182 | 2021 |
C3-dependent mechanism of microglial priming relevant to multiple sclerosis V Ramaglia, TR Hughes, RM Donev, MM Ruseva, X Wu, I Huitinga, ... Proceedings of the National Academy of Sciences 109 (3), 965-970, 2012 | 171 | 2012 |
Longterm quiescent cells in the aged human subventricular neurogenic system specifically express GFAP‐δ SA Van Den Berge, J Middeldorp, CE Zhang, MA Curtis, BW Leonard, ... Aging cell 9 (3), 313-326, 2010 | 171 | 2010 |