Glycogen synthase kinase-3 is rapidly inactivated in response to insulin and phosphorylates eukaryotic initiation factor eIF-2B GI Welsh, CG Proud Biochemical Journal 294 (3), 625-629, 1993 | 544 | 1993 |
Insulin signaling to the glomerular podocyte is critical for normal kidney function GI Welsh, LJ Hale, V Eremina, M Jeansson, Y Maezawa, R Lennon, ... Cell metabolism 12 (4), 329-340, 2010 | 496 | 2010 |
Regulation of eukaryotic initiation factor eIF2B: glycogen synthase kinase-3 phosphorylates a conserved serine which undergoes dephosphorylation in response to insulin GI Welsh, CM Miller, AJ Loughlin, NT Price, CG Proud FEBS letters 421 (2), 125-130, 1998 | 398 | 1998 |
The human glomerular podocyte is a novel target for insulin action RJM Coward, GI Welsh, J Yang, C Tasman, R Lennon, A Koziell, ... Diabetes 54 (11), 3095-3102, 2005 | 336 | 2005 |
The podocyte cytoskeleton—key to a functioning glomerulus in health and disease GI Welsh, MA Saleem Nature reviews Nephrology 8 (1), 14-21, 2012 | 286 | 2012 |
Regulation of protein kinase B and glycogen synthase kinase-3 by insulin and β-adrenergic agonists in rat epididymal fat cells: activation of protein kinase B by wortmannin … SK Moule, GI Welsh, NJ Edgell, EJ Foulstone, CG Proud, RM Denton Journal of Biological Chemistry 272 (12), 7713-7719, 1997 | 286 | 1997 |
Genomic and clinical profiling of a national nephrotic syndrome cohort advocates a precision medicine approach to disease management A Bierzynska, HJ McCarthy, K Soderquest, ES Sen, E Colby, WY Ding, ... Kidney international 91 (4), 937-947, 2017 | 279 | 2017 |
WT1 mutants reveal SRPK1 to be a downstream angiogenesis target by altering VEGF splicing EM Amin, S Oltean, J Hua, MVR Gammons, M Hamdollah-Zadeh, ... Cancer cell 20 (6), 768-780, 2011 | 277 | 2011 |
Wortmannin inhibits the effects of insulin and serum on the activities of glycogen synthase kinase-3 and mitogen-activated protein kinase GI Welsh, EJ Foulstone, SW Young, JM Tavare, CG Proud Biochemical Journal 303 (1), 15-20, 1994 | 239 | 1994 |
Simultaneous sequencing of 24 genes associated with steroid-resistant nephrotic syndrome HJ McCarthy, A Bierzynska, M Wherlock, M Ognjanovic, L Kerecuk, ... Clinical Journal of the American Society of Nephrology 8 (4), 637-648, 2013 | 217 | 2013 |
Reactive oxygen species modulate the barrier function of the human glomerular endothelial glycocalyx A Singh, RD Ramnath, RR Foster, EC Wylie, V Fridén, I Dasgupta, ... PloS one 8 (2), e55852, 2013 | 188 | 2013 |
Protein kinase B phosphorylation of PIKfyve regulates the trafficking of GLUT4 vesicles DC Berwick, GC Dell, GI Welsh, KJ Heesom, I Hers, LM Fletcher, ... Journal of cell science 117 (25), 5985-5993, 2004 | 185 | 2004 |
GSK3: a SHAGGY frog story GI Welsh, C Wilson, CG Proud Trends in cell biology 6 (7), 274-279, 1996 | 180 | 1996 |
Role for the microtubule cytoskeleton in GLUT4 vesicle trafficking and in the regulation of insulin-stimulated glucose uptake LM FLETCHER, GI WELSH, PB OATEY, JM TAVARÉ Biochemical Journal 352 (2), 267-276, 2000 | 176 | 2000 |
Nephrin is critical for the action of insulin on human glomerular podocytes RJM Coward, GI Welsh, A Koziell, S Hussain, R Lennon, L Ni, JM Tavaré, ... Diabetes 56 (4), 1127-1135, 2007 | 174 | 2007 |
Molecular and cellular events mediating glomerular podocyte dysfunction and depletion in diabetes mellitus P Anil Kumar, GI Welsh, MA Saleem, RK Menon Frontiers in endocrinology 5, 108455, 2014 | 173 | 2014 |
Hemopexin induces nephrin-dependent reorganization of the actin cytoskeleton in podocytes R Lennon, A Singh, GI Welsh, RJ Coward, S Satchell, L Ni, PW Mathieson, ... Journal of the American Society of Nephrology 19 (11), 2140-2149, 2008 | 167 | 2008 |
Nephrin—signature molecule of the glomerular podocyte? GI Welsh, MA Saleem The Journal of Pathology: A Journal of the Pathological Society of Great …, 2010 | 166 | 2010 |
Saturated fatty acids induce insulin resistance in human podocytes: implications for diabetic nephropathy R Lennon, D Pons, MA Sabin, C Wei, JP Shield, RJ Coward, JM Tavaré, ... Nephrology Dialysis Transplantation 24 (11), 3288-3296, 2009 | 165 | 2009 |
Role of protein kinase B in insulin-regulated glucose uptake GI Welsh, I Hers, DC Berwick, G Dell, M Wherlock, R Birkin, S Leney, ... Biochemical Society Transactions 33 (2), 346-349, 2005 | 162 | 2005 |