1, 2, 3‐Triazole in heterocyclic compounds, endowed with biological activity, through 1, 3‐dipolar cycloadditions A Lauria, R Delisi, F Mingoia, A Terenzi, A Martorana, G Barone, ... European Journal of Organic Chemistry 2014 (16), 3289-3306, 2014 | 310 | 2014 |
Synthesis and antitumor properties of 2, 5-bis (3′-indolyl) thiophenes: Analogues of marine alkaloid nortopsentin P Diana, A Carbone, P Barraja, A Montalbano, A Martorana, G Dattolo, ... Bioorganic & medicinal chemistry letters 17 (8), 2342-2346, 2007 | 122 | 2007 |
3, 5-Bis (3′-indolyl) pyrazoles, analogues of marine alkaloid nortopsentin: Synthesis and antitumor properties P Diana, A Carbone, P Barraja, A Martorana, O Gia, L DallaVia, ... Bioorganic & medicinal chemistry letters 17 (22), 6134-6137, 2007 | 121 | 2007 |
Isoindolo[2,1-a]quinoxaline Derivatives, Novel Potent Antitumor Agents with Dual Inhibition of Tubulin Polymerization and Topoisomerase I P Diana, A Martorana, P Barraja, A Montalbano, G Dattolo, G Cirrincione, ... Journal of medicinal chemistry 51 (8), 2387-2399, 2008 | 115 | 2008 |
Selective G-quadruplex stabilizers: Schiff-base metal complexes with anticancer activity A Terenzi, R Bonsignore, A Spinello, C Gentile, A Martorana, C Ducani, ... RSC advances 4 (63), 33245-33256, 2014 | 91 | 2014 |
Hsp60, a novel target for antitumor therapy: structure-function features and prospective drugs design A Pace, G Barone, A Lauria, A Martorana, A Palumbo Piccionello, ... Current pharmaceutical design 19 (15), 2757-2764, 2013 | 90 | 2013 |
Nanostructured lipid carriers-containing anticancer compounds: preparation, characterization, and cytotoxicity studies ML Bondì, EF Craparo, G Giammona, M Cervello, A Azzolina, P Diana, ... Drug Delivery 14 (2), 61-67, 2007 | 89 | 2007 |
Isoindolo [2, 1-c] benzo [1, 2, 4] triazines: a new ring system with antiproliferative activity P Diana, A Martorana, P Barraja, A Lauria, A Montalbano, AM Almerico, ... Bioorganic & Medicinal Chemistry 15 (1), 343-349, 2007 | 58 | 2007 |
Synthesis, antiproliferative activity, and in silico insights of new 3-benzoylamino-benzo [b] thiophene derivatives A Martorana, C Gentile, U Perricone, AP Piccionello, R Bartolotta, ... European journal of medicinal chemistry 90, 537-546, 2015 | 54 | 2015 |
Lead optimization through VLAK protocol: New annelated pyrrolo-pyrimidine derivatives as antitumor agents A Lauria, C Patella, I Abbate, A Martorana, AM Almerico European journal of medicinal chemistry 55, 375-383, 2012 | 52 | 2012 |
New annelated thieno [2, 3-e][1, 2, 3] triazolo [1, 5-a] pyrimidines, with potent anticancer activity, designed through VLAK protocol A Lauria, I Abbate, C Patella, A Martorana, G Dattolo, AM Almerico European journal of medicinal chemistry 62, 416-424, 2013 | 51 | 2013 |
G-quadruplex vs. duplex-DNA binding of nickel (II) and zinc (II) Schiff base complexes R Bonsignore, A Terenzi, A Spinello, A Martorana, A Lauria, AM Almerico, ... Journal of Inorganic Biochemistry 161, 115-121, 2016 | 46 | 2016 |
Heterocyclic scaffolds for the treatment of Alzheimer’s disease A Martorana, V Giacalone, R Bonsignore, A Pace, C Gentile, I Pibiri, ... Current pharmaceutical design 22 (26), 3971-3995, 2016 | 46 | 2016 |
Kinase inhibitors in multitargeted cancer therapy C Gentile, A Martorana, A Lauria, R Bonsignore Current medicinal chemistry 24 (16), 1671-1686, 2017 | 42 | 2017 |
Curcumin-like compounds designed to modify amyloid beta peptide aggregation patterns A Battisti, AP Piccionello, A Sgarbossa, S Vilasi, C Ricci, F Ghetti, ... RSC advances 7 (50), 31714-31724, 2017 | 42 | 2017 |
Quinoline-based molecules targeting c-Met, EGF, and VEGF receptors and the proteins involved in related carcinogenic pathways A Martorana, G La Monica, A Lauria Molecules 25 (18), 4279, 2020 | 39 | 2020 |
New benzothieno [3, 2-d]-1, 2, 3-triazines with antiproliferative activity: Synthesis, spectroscopic studies, and biological activity A Lauria, A Alfio, R Bonsignore, C Gentile, A Martorana, G Gennaro, ... Bioorganic & Medicinal Chemistry Letters 24 (15), 3291-3297, 2014 | 31 | 2014 |
An unexpected Dimroth rearrangement leading to annelated thieno [3, 2-d][1, 2, 3] triazolo [1, 5-a] pyrimidines with potent antitumor activity A Lauria, C Patella, I Abbate, A Martorana, AM Almerico European Journal of Medicinal Chemistry 65, 381-388, 2013 | 31 | 2013 |
DRUDIT: Web-based DRUgs DIscovery Tools to design small molecules as modulators of biological targets A Lauria, S Mannino, C Gentile, G Mannino, A Martorana, D Peri Bioinformatics 36 (5), 1562-1569, 2020 | 26 | 2020 |
The repurposing of old drugs or unsuccessful lead compounds by in silico approaches: new advances and perspectives A Martorana, U Perricone, A Lauria Current Topics in Medicinal Chemistry 16 (19), 2088-2106, 2016 | 26 | 2016 |