Aptamers as targeted therapeutics: current potential and challenges J Zhou, J Rossi Nature reviews Drug discovery 16 (3), 181-202, 2017 | 1796 | 2017 |
Novel dual inhibitory function aptamer–siRNA delivery system for HIV-1 therapy J Zhou, H Li, S Li, J Zaia, JJ Rossi Molecular Therapy 16 (8), 1481-1489, 2008 | 383 | 2008 |
PAMAM dendrimers for efficient siRNA delivery and potent gene silencing J Zhou, J Wu, N Hafdi, JP Behr, P Erbacher, L Peng Chemical communications, 2362-2364, 2006 | 353 | 2006 |
Selection, characterization and application of new RNA HIV gp 120 aptamers for facile delivery of Dicer substrate siRNAs into HIV infected cells J Zhou, P Swiderski, H Li, J Zhang, CP Neff, R Akkina, JJ Rossi Nucleic acids research 37 (9), 3094-3109, 2009 | 345 | 2009 |
An aptamer-siRNA chimera suppresses HIV-1 viral loads and protects from helper CD4+ T cell decline in humanized mice CP Neff, J Zhou, L Remling, J Kuruvilla, J Zhang, H Li, DD Smith, ... Science translational medicine 3 (66), 66ra6-66ra6, 2011 | 323 | 2011 |
Cell-type-specific, aptamer-functionalized agents for targeted disease therapy J Zhou, JJ Rossi Molecular Therapy-Nucleic Acids 3, 2014 | 278 | 2014 |
Nanoparticle-based delivery of RNAi therapeutics: progress and challenges J Zhou, KT Shum, JC Burnett, JJ Rossi Pharmaceuticals 6 (1), 85-107, 2013 | 231 | 2013 |
Adaptive amphiphilic dendrimer‐based nanoassemblies as robust and versatile siRNA delivery systems X Liu, J Zhou, T Yu, C Chen, Q Cheng, K Sengupta, Y Huang, H Li, C Liu, ... Angewandte Chemie International Edition 53 (44), 11822-11827, 2014 | 210 | 2014 |
Cell-specific aptamer-mediated targeted drug delivery J Zhou, JJ Rossi Oligonucleotides 21 (1), 1-10, 2011 | 200 | 2011 |
Systemic administration of combinatorial dsiRNAs via nanoparticles efficiently suppresses HIV-1 infection in humanized mice J Zhou, CP Neff, X Liu, J Zhang, H Li, DD Smith, P Swiderski, T Aboellail, ... Molecular Therapy 19 (12), 2228-2238, 2011 | 185 | 2011 |
Aptamer-targeted cell-specific RNA interference J Zhou, JJ Rossi Silence 1, 1-10, 2010 | 168 | 2010 |
Current advances in aptamers for cancer diagnosis and therapy S Hori, A Herrera, JJ Rossi, J Zhou Cancers 10 (1), 9, 2018 | 165 | 2018 |
Current progress of RNA aptamer-based therapeutics J Zhou, ML Bobbin, JC Burnett, JJ Rossi Frontiers in genetics 3, 234, 2012 | 155 | 2012 |
Functional in vivo delivery of multiplexed anti-HIV-1 siRNAs via a chemically synthesized aptamer with a sticky bridge J Zhou, CP Neff, P Swiderski, H Li, DD Smith, T Aboellail, ... Molecular Therapy 21 (1), 192-200, 2013 | 142 | 2013 |
Genome-wide profiling identified a set of miRNAs that are differentially expressed in glioblastoma stem cells and normal neural stem cells MF Lang, S Yang, C Zhao, G Sun, K Murai, X Wu, J Wang, H Gao, ... PloS one 7 (4), e36248, 2012 | 133 | 2012 |
Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 inhibition J Zhou, Y Shu, P Guo, DD Smith, JJ Rossi Methods 54 (2), 284-294, 2011 | 112 | 2011 |
Importance of size-to-charge ratio in construction of stable and uniform nanoscale RNA/dendrimer complexes XC Shen, J Zhou, X Liu, J Wu, F Qu, ZL Zhang, DW Pang, G Quéléver, ... Organic & biomolecular chemistry 5 (22), 3674-3681, 2007 | 109 | 2007 |
Promoting siRNA delivery via enhanced cellular uptake using an arginine-decorated amphiphilic dendrimer X Liu, C Liu, J Zhou, C Chen, F Qu, JJ Rossi, P Rocchi, L Peng Nanoscale 7 (9), 3867-3875, 2015 | 104 | 2015 |
High throughput sequencing analysis of RNA libraries reveals the influences of initial library and PCR methods on SELEX efficiency M Takahashi, X Wu, M Ho, P Chomchan, JJ Rossi, JC Burnett, J Zhou Scientific reports 6 (1), 33697, 2016 | 103 | 2016 |
Structurally flexible triethanolamine core PAMAM dendrimers are effective nanovectors for DNA transfection in vitro and in vivo to the mouse thymus X Liu, J Wu, M Yammine, J Zhou, P Posocco, S Viel, C Liu, F Ziarelli, ... Bioconjugate Chemistry 22 (12), 2461-2473, 2011 | 97 | 2011 |