G‐quadruplex‐binding small molecules ameliorate C9orf72 FTD/ALS pathology in vitro and in vivo R Simone, R Balendra, TG Moens, E Preza, KM Wilson, A Heslegrave, ... EMBO molecular medicine 10 (1), 22-31, 2018 | 210 | 2018 |
The role of histone acetylation in SMN gene expression LE Kernochan, ML Russo, NS Woodling, TN Huynh, AM Avila, ... Human molecular genetics 14 (9), 1171-1182, 2005 | 201 | 2005 |
The prostaglandin E2 E-prostanoid 4 receptor exerts anti-inflammatory effects in brain innate immunity J Shi, J Johansson, NS Woodling, Q Wang, TJ Montine, K Andreasson The Journal of Immunology 184 (12), 7207-7218, 2010 | 170 | 2010 |
Prostaglandin signaling suppresses beneficial microglial function in Alzheimer’s disease models JU Johansson, NS Woodling, Q Wang, M Panchal, X Liang, ... The Journal of clinical investigation 125 (1), 350-364, 2015 | 152 | 2015 |
A Drosophila model of neuronopathic Gaucher disease demonstrates lysosomal-autophagic defects and altered mTOR signalling and is functionally rescued by rapamycin KJ Kinghorn, S Grönke, JI Castillo-Quan, NS Woodling, L Li, E Sirka, ... Journal of Neuroscience 36 (46), 11654-11670, 2016 | 138 | 2016 |
Suppression of Alzheimer-associated inflammation by microglial prostaglandin-E2 EP4 receptor signaling NS Woodling, Q Wang, PG Priyam, P Larkin, J Shi, JU Johansson, ... Journal of Neuroscience 34 (17), 5882-5894, 2014 | 117 | 2014 |
Inflammatory prostaglandin E2 signaling in a mouse model of Alzheimer disease J Shi, Q Wang, JU Johansson, X Liang, NS Woodling, P Priyam, TM Loui, ... Annals of neurology 72 (5), 788-798, 2012 | 114 | 2012 |
Signaling via the prostaglandin E 2 receptor EP4 exerts neuronal and vascular protection in a mouse model of cerebral ischemia X Liang, L Lin, NS Woodling, Q Wang, C Anacker, T Pan, M Merchant, ... The Journal of clinical investigation 121 (11), 4362-4371, 2011 | 108 | 2011 |
Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis JL Grant, EEB Ghosn, RC Axtell, K Herges, HF Kuipers, NS Woodling, ... Science translational medicine 4 (145), 145ra105-145ra105, 2012 | 101 | 2012 |
Cyclooxygenase inhibition targets neurons to prevent early behavioural decline in Alzheimer’s disease model mice NS Woodling, D Colas, Q Wang, P Minhas, M Panchal, X Liang, ... Brain 139 (7), 2063-2081, 2016 | 97 | 2016 |
Suppression of inflammation with conditional deletion of the prostaglandin E2 EP2 receptor in macrophages and brain microglia JU Johansson, S Pradhan, LA Lokteva, NS Woodling, N Ko, HD Brown, ... Journal of Neuroscience 33 (40), 16016-16032, 2013 | 91 | 2013 |
Amyloid beta protein-induced zinc sequestration leads to synaptic loss via dysregulation of the ProSAP2/Shank3 scaffold AM Grabrucker, MJ Schmeisser, PT Udvardi, M Arons, M Schoen, ... Mol Neurodegener 6 (65), 20797-20811, 2011 | 79 | 2011 |
Deficiency in neuronal TGF-β signaling leads to nigrostriatal degeneration and activation of TGF-β signaling protects against MPTP neurotoxicity in mice I Tesseur, A Nguyen, B Chang, L Li, NS Woodling, T Wyss-Coray, J Luo Journal of Neuroscience 37 (17), 4584-4592, 2017 | 73 | 2017 |
Shifting equilibriums in Alzheimer’s disease: The complex roles of microglia in neuroinflammation, neuronal survival and neurogenesis SC Gray, KJ Kinghorn, NS Woodling Neural Regeneration Research 15 (7), 1208-1219, 2020 | 72 | 2020 |
Bidirectional nucleolar dysfunction in C9orf72 frontotemporal lobar degeneration S Mizielinska, CE Ridler, R Balendra, A Thoeng, NS Woodling, ... Acta neuropathologica communications 5, 1-11, 2017 | 62 | 2017 |
Untangling the web: toxic and protective effects of neuroinflammation and PGE2 signaling in Alzheimer’s disease NS Woodling, KI Andreasson ACS Chemical Neuroscience 7 (4), 454-463, 2016 | 59 | 2016 |
Fine-tuning autophagy maximises lifespan and is associated with changes in mitochondrial gene expression in Drosophila I Bjedov, HM Cochemé, A Foley, D Wieser, NS Woodling, JI Castillo-Quan, ... PLoS genetics 16 (11), e1009083, 2020 | 53 | 2020 |
Inflammatory cyclooxygenase activity and PGE2 signaling in models of Alzheimer’s disease J U Johansson, N S Woodling, J Shi, K I Andreasson Current immunology reviews 11 (2), 125-131, 2015 | 28 | 2015 |
The neuronal receptor tyrosine kinase Alk is a target for longevity NS Woodling, B Aleyakpo, MC Dyson, LJ Minkley, A Rajasingam, ... Aging Cell 19 (5), e13137, 2020 | 23 | 2020 |
An EP overexpression screen for genetic modifiers of Notch pathway function in Drosophila melanogaster LE Hall, SJ Alexander, M Chang, NS Woodling, B Yedvobnick Genetical research 83 (02), 71-82, 2004 | 21 | 2004 |