Snail blocks the cell cycle and confers resistance to cell death S Vega, AV Morales, OH Ocaña, F Valdés, I Fabregat, MA Nieto Genes & development 18 (10), 1131-1143, 2004 | 1045 | 2004 |
TGF‐β signalling and liver disease I Fabregat, J Moreno‐Càceres, A Sánchez, S Dooley, B Dewidar, ... The FEBS journal 283 (12), 2219-2232, 2016 | 601 | 2016 |
Reactive oxygen species (ROS) mediates the mitochondrial‐dependent apoptosis induced by transforming growth factor ß in fetal hepatocytes B HERRERA, AM ÁLVAREZ, A SÁNCHEZ, M FERNÁNDEZ, ... The FASEB Journal 15 (3), 741-751, 2001 | 378 | 2001 |
Dysregulation of apoptosis in hepatocellular carcinoma cells I Fabregat World journal of gastroenterology: WJG 15 (5), 513, 2009 | 342 | 2009 |
Apoptosis Induced by Transforming Growth Factor-β in Fetal Hepatocyte Primary Cultures: INVOLVEMENT OF REACTIVE OXYGEN INTERMEDIATES (∗) A Sánchez, AM Alvarez, M Benito, I Fabregat Journal of Biological Chemistry 271 (13), 7416-7422, 1996 | 330 | 1996 |
European contribution to the study of ROS: A summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS) J Egea, I Fabregat, YM Frapart, P Ghezzi, A Görlach, T Kietzmann, ... Redox biology 13, 94-162, 2017 | 319 | 2017 |
TGF-β and the Tissue Microenvironment: Relevance in Fibrosis and Cancer L Caja, F Dituri, S Mancarella, D Caballero-Diaz, A Moustakas, ... International journal of molecular sciences 19 (5), 1294, 2018 | 311 | 2018 |
Transforming growth factor-β-induced cell plasticity in liver fibrosis and hepatocarcinogenesis I Fabregat, D Caballero-Díaz Frontiers in oncology 8, 357, 2018 | 306 | 2018 |
The epithelial mesenchymal transition confers resistance to the apoptotic effects of transforming growth factor β in fetal rat hepatocytes F Valdés, AM Alvarez, A Locascio, S Vega, B Herrera, M Fernández, ... Molecular cancer research 1 (1), 68-78, 2002 | 293 | 2002 |
Survival and apoptosis: a dysregulated balance in liver cancer I Fabregat, C Roncero, M Fernández Liver International 27 (2), 155-162, 2007 | 288 | 2007 |
Upregulation of the NADPH oxidase NOX4 by TGF-beta in hepatocytes is required for its pro-apoptotic activity I Carmona-Cuenca, C Roncero, P Sancho, L Caja, N Fausto, ... Journal of hepatology 49 (6), 965-976, 2008 | 260 | 2008 |
TGF-beta signaling in cancer treatment I Fabregat, J Fernando, J Mainez, P Sancho Current pharmaceutical design 20 (17), 2934-2947, 2014 | 223 | 2014 |
Snail1 suppresses TGF-β-induced apoptosis and is sufficient to trigger EMT in hepatocytes DL Franco, J Mainez, S Vega, P Sancho, MM Murillo, CA de Frutos, ... Journal of cell science 123 (20), 3467-3477, 2010 | 186 | 2010 |
Molecular mechanisms of insulin resistance in IRS-2-deficient hepatocytes AM Valverde, DJ Burks, I Fabregat, TL Fisher, J Carretero, MF White, ... Diabetes 52 (9), 2239-2248, 2003 | 178 | 2003 |
NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development P Sancho, J Mainez, E Crosas-Molist, C Roncero, ... Public Library of Science 7 (9), e45285, 2012 | 177 | 2012 |
Involvement of EGF receptor and c-Src in the survival signals induced by TGF-β1 in hepatocytes MM Murillo, G Castillo, A Sanchez, M Fernandez, I Fabregat Oncogene 24 (28), 4580-4587, 2005 | 170 | 2005 |
Source of early reactive oxygen species in the apoptosis induced by transforming growth factor-β in fetal rat hepatocytes B Herrera, MM Murillo, A Alvarez-Barrientos, J Beltrán, M Fernández, ... Free Radical Biology and Medicine 36 (1), 16-26, 2004 | 166 | 2004 |
Role of NADPH oxidases in the redox biology of liver fibrosis E Crosas-Molist, I Fabregat Redox Biology 6, 106-111, 2015 | 156 | 2015 |
New insights into the crossroads between EMT and stemness in the context of cancer I Fabregat, A Malfettone, J Soukupova Journal of clinical medicine 5 (3), 37, 2016 | 155 | 2016 |
The transforming growth factor‐beta (TGF‐β) mediates acquisition of a mesenchymal stem cell‐like phenotype in human liver cells L Caja, E Bertran, J Campbell, N Fausto, I Fabregat Journal of cellular physiology 226 (5), 1214-1223, 2011 | 153 | 2011 |