| Treatment of nonalcoholic fatty liver disease: role of AMPK BK Smith, K Marcinko, EM Desjardins, JS Lally, RJ Ford, GR Steinberg American Journal of Physiology-Endocrinology and Metabolism 311 (4), E730-E740, 2016 | 452 | 2016 |
| Lack of adipocyte AMPK exacerbates insulin resistance and hepatic steatosis through brown and beige adipose tissue function EP Mottillo, EM Desjardins, JD Crane, BK Smith, AE Green, S Ducommun, ... Cell metabolism 24 (1), 118-129, 2016 | 306 | 2016 |
| Muramyl dipeptide-based postbiotics mitigate obesity-induced insulin resistance via IRF4 JF Cavallari, MD Fullerton, BM Duggan, KP Foley, E Denou, BK Smith, ... Cell metabolism 25 (5), 1063-1074. e3, 2017 | 184 | 2017 |
| Emerging role of AMPK in brown and beige adipose tissue (BAT): implications for obesity, insulin resistance, and type 2 diabetes EM Desjardins, GR Steinberg Current diabetes reports 18, 1-9, 2018 | 176 | 2018 |
| PGC-1α modulates denervation-induced mitophagy in skeletal muscle A Vainshtein, EMA Desjardins, A Armani, M Sandri, DA Hood Skeletal muscle 5, 1-17, 2015 | 170 | 2015 |
| Mitochondria-localized AMPK responds to local energetics and contributes to exercise and energetic stress-induced mitophagy JC Drake, RJ Wilson, RC Laker, Y Guan, HR Spaulding, AS Nichenko, ... Proceedings of the National Academy of Sciences 118 (37), e2025932118, 2021 | 104 | 2021 |
| Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms SL Pinkosky, JW Scott, EM Desjardins, BK Smith, EA Day, RJ Ford, ... Nature metabolism 2 (9), 873-881, 2020 | 103 | 2020 |
| Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia MR Morrow, B Batchuluun, J Wu, E Ahmadi, JM Leroux, ... Cell Metabolism 34 (6), 919-936. e8, 2022 | 88 | 2022 |
| Salsalate (salicylate) uncouples mitochondria, improves glucose homeostasis, and reduces liver lipids independent of AMPK-β1 BK Smith, RJ Ford, EM Desjardins, AE Green, MC Hughes, VP Houde, ... Diabetes 65 (11), 3352-3361, 2016 | 76 | 2016 |
| The pesticide chlorpyrifos promotes obesity by inhibiting diet-induced thermogenesis in brown adipose tissue B Wang, EE Tsakiridis, S Zhang, A Llanos, EM Desjardins, JM Yabut, ... Nature communications 12 (1), 5163, 2021 | 66 | 2021 |
| FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose … EP Mottillo, EM Desjardins, AM Fritzen, VZ Zou, JD Crane, JM Yabut, ... Molecular metabolism 6 (6), 471-481, 2017 | 58 | 2017 |
| GDF15 promotes weight loss by enhancing energy expenditure in muscle D Wang, LK Townsend, GJ DesOrmeaux, SM Frangos, B Batchuluun, ... Nature 619 (7968), 143-150, 2023 | 54 | 2023 |
| Ablating the protein TBC1D1 impairs contraction-induced sarcolemmal glucose transporter 4 redistribution but not insulin-mediated responses in rats J Whitfield, S Paglialunga, BK Smith, PM Miotto, G Simnett, HL Robson, ... Journal of Biological Chemistry 292 (40), 16653-16664, 2017 | 52 | 2017 |
| Lower brown adipose tissue activity is associated with non-alcoholic fatty liver disease but not changes in the gut microbiota BA Ahmed, FJ Ong, NG Barra, DP Blondin, E Gunn, SM Oreskovich, ... Cell Reports Medicine 2 (9), 2021 | 47 | 2021 |
| Genetic deletion of mast cell serotonin synthesis prevents the development of obesity and insulin resistance JM Yabut, EM Desjardins, EJ Chan, EA Day, JM Leroux, B Wang, ... Nature communications 11 (1), 463, 2020 | 45 | 2020 |
| The SGLT2 inhibitor canagliflozin suppresses lipid synthesis and interleukin-1 beta in ApoE deficient mice EA Day, RJ Ford, JH Lu, R Lu, L Lundenberg, EM Desjardins, AE Green, ... Biochemical Journal 477 (12), 2347-2361, 2020 | 33 | 2020 |
| Myostatin inhibition therapy for insulin-deficient type 1 diabetes SK Coleman, IA Rebalka, DM D’Souza, N Deodhare, EM Desjardins, ... Scientific reports 6 (1), 32495, 2016 | 33 | 2016 |
| The caveolin-1 regulated protein follistatin protects against diabetic kidney disease D Zhang, AL Gava, R Van Krieken, N Mehta, R Li, B Gao, EM Desjardins, ... Kidney international 96 (5), 1134-1149, 2019 | 22 | 2019 |
| Compound-and fiber type-selective requirement of AMPKγ3 for insulin-independent glucose uptake in skeletal muscle P Rhein, EM Desjardins, P Rong, D Ahwazi, N Bonhoure, J Stolte, ... Molecular Metabolism 51, 101228, 2021 | 15 | 2021 |
| The phosphorylation of AMPKβ1 is critical for increasing autophagy and maintaining mitochondrial homeostasis in response to fatty acids EM Desjardins, BK Smith, EA Day, S Ducommun, MJ Sanders, ... Proceedings of the National Academy of Sciences 119 (48), e2119824119, 2022 | 10 | 2022 |
