Large-scale generation of functional mRNA-encapsulating exosomes via cellular nanoporation Z Yang, J Shi, J Xie, Y Wang, J Sun, T Liu, Y Zhao, X Zhao, X Wang, Y Ma, ... Nature biomedical engineering 4 (1), 69-83, 2020 | 512 | 2020 |
Functional exosome-mimic for delivery of siRNA to cancer: in vitro and in vivo evaluation Z Yang, J Xie, J Zhu, C Kang, C Chiang, X Wang, X Wang, T Kuang, ... Journal of Controlled Release 243, 160-171, 2016 | 211 | 2016 |
3D nanochannel electroporation for high-throughput cell transfection with high uniformity and dosage control L Chang, P Bertani, D Gallego-Perez, Z Yang, F Chen, C Chiang, ... Nanoscale 8 (1), 243-252, 2016 | 115 | 2016 |
Magnetic tweezers‐based 3D microchannel electroporation for high‐throughput gene transfection in living cells L Chang, M Howdyshell, WC Liao, CL Chiang, D Gallego‐Perez, Z Yang, ... Small 11 (15), 1818-1828, 2015 | 106 | 2015 |
Dielectrophoresis-assisted 3D nanoelectroporation for non-viral cell transfection in adoptive immunotherapy L Chang, D Gallego-Perez, X Zhao, P Bertani, Z Yang, CL Chiang, ... Lab on a Chip 15 (15), 3147-3153, 2015 | 105 | 2015 |
Controllable large‐scale transfection of primary mammalian cardiomyocytes on a nanochannel array platform L Chang, D Gallego‐Perez, CL Chiang, P Bertani, T Kuang, Y Sheng, ... Small 12 (43), 5971-5980, 2016 | 72 | 2016 |
Intradermally delivered mRNA-encapsulating extracellular vesicles for collagen-replacement therapy Y You, Y Tian, Z Yang, J Shi, KJ Kwak, Y Tong, AP Estania, J Cao, ... Nature biomedical engineering 7 (7), 887-900, 2023 | 66 | 2023 |
Modeling of cancer metastasis and drug resistance via biomimetic nano-cilia and microfluidics CT Kuo, CL Chiang, CH Chang, HK Liu, GS Huang, RYJ Huang, H Lee, ... Biomaterials 35 (5), 1562-1571, 2014 | 65 | 2014 |
Dielectrophoresis-based cellular microarray chip for anticancer drug screening in perfusion microenvironments LC Hsiung, CL Chiang, CH Wang, YH Huang, CT Kuo, JY Cheng, CH Lin, ... Lab on a Chip 11 (14), 2333-2342, 2011 | 65 | 2011 |
Targeting the RAS/MAPK pathway with miR-181a in acute myeloid leukemia X Huang, S Schwind, R Santhanam, AK Eisfeld, C Chiang, M Lankenau, ... Oncotarget 7 (37), 59273, 2016 | 61 | 2016 |
Indole-3-carbinol inhibits tumorigenicity of hepatocellular carcinoma cells via suppression of microRNA-21 and upregulation of phosphatase and tensin homolog X Wang, H He, Y Lu, W Ren, K Teng, C Chiang, Z Yang, B Yu, S Hsu, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (1), 244-253, 2015 | 58 | 2015 |
Configurable 2D and 3D spheroid tissue cultures on bioengineered surfaces with acquisition of epithelial–mesenchymal transition characteristics CT Kuo, CL Chiang, R Yun-Ju Huang, H Lee, AM Wo NPG Asia Materials 4 (9), e27-e27, 2012 | 58 | 2012 |
Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B-cell cytotoxicity in chronic lymphocytic leukemia R Mani, Y Mao, FW Frissora, CL Chiang, J Wang, Y Zhao, Y Wu, B Yu, ... Leukemia 29 (2), 346-355, 2015 | 55 | 2015 |
Micro-/nano-electroporation for active gene delivery LJL Zhaogang Yang, Lingqian Chang, Chi-ling Chiang Current Pharmaceutical Design 21 (42 Issues), 2015 | 47 | 2015 |
Lysophosphatidic acid induces erythropoiesis through activating lysophosphatidic acid receptor 3 CL Chiang, SSA Chen, SJ Lee, KC Tsao, PL Chu, CH Wen, SM Hwang, ... Stem cells 29 (11), 1763-1773, 2011 | 43 | 2011 |
ROR1-targeted delivery of miR-29b induces cell cycle arrest and therapeutic benefit in vivo in a CLL mouse model CL Chiang, S Goswami, FW Frissora, Z Xie, PS Yan, R Bundschuh, ... Blood, The Journal of the American Society of Hematology 134 (5), 432-444, 2019 | 41 | 2019 |
From nanoparticles to cancer nanomedicine: old problems with new solutions CL Chiang, MH Cheng, CH Lin Nanomaterials 11 (7), 1727, 2021 | 33 | 2021 |
A novel 96well-formatted micro-gap plate enabling drug response profiling on primary tumour samples WY Ma, LC Hsiung, CH Wang, CL Chiang, CH Lin, CS Huang, AM Wo Scientific reports 5 (1), 9656, 2015 | 32 | 2015 |
Pharmacological activation of lysophosphatidic acid receptors regulates erythropoiesis KH Lin, YH Ho, JC Chiang, MW Li, SH Lin, WM Chen, CL Chiang, YN Lin, ... Scientific reports 6 (1), 27050, 2016 | 31 | 2016 |
PP2A is a therapeutically targetable driver of cell fate decisions via a c-Myc/p21 axis in human and murine acute myeloid leukemia S Goswami, R Mani, J Nunes, CL Chiang, K Zapolnik, E Hu, F Frissora, ... Blood, The Journal of the American Society of Hematology 139 (9), 1340-1358, 2022 | 25* | 2022 |