Using nature’s blueprint to expand catalysis with Earth-abundant metals RM Bullock, JG Chen, L Gagliardi, PJ Chirik, OK Farha, CH Hendon, ... Science 369 (6505), eabc3183, 2020 | 371 | 2020 |
Catalytic asymmetric Hiyama cross-couplings of racemic α-bromo esters X Dai, NA Strotman, GC Fu Journal of the American Chemical Society 130 (11), 3302-3303, 2008 | 292 | 2008 |
Hiyama reactions of activated and unactivated secondary alkyl halides catalyzed by a nickel/norephedrine complex NA Strotman, S Sommer, GC Fu Angewandte Chemie International Edition 46 (19), 3556-3558, 2007 | 186 | 2007 |
Electrochemically driven cross-electrophile coupling of alkyl halides W Zhang, L Lu, W Zhang, Y Wang, SD Ware, J Mondragon, J Rein, ... Nature 604 (7905), 292-297, 2022 | 151 | 2022 |
Highly regioselective palladium-catalyzed direct arylation of oxazole at C-2 or C-5 with aryl bromides, chlorides, and triflates NA Strotman, HR Chobanian, Y Guo, J He, JE Wilson Organic letters 12 (16), 3578-3581, 2010 | 151 | 2010 |
Regioselective Bromination of Fused Heterocyclic N-Oxides SE Wengryniuk, A Weickgenannt, C Reiher, NA Strotman, K Chen, ... Organic letters 15 (4), 792-795, 2013 | 139 | 2013 |
Reaction development and mechanistic study of a ruthenium catalyzed intramolecular asymmetric reductive amination en route to the dual orexin inhibitor suvorexant (MK-4305) NA Strotman, CA Baxter, KMJ Brands, E Cleator, SW Krska, RA Reamer, ... Journal of the American Chemical Society 133 (21), 8362-8371, 2011 | 124 | 2011 |
Asymmetric synthesis of telcagepant, a CGRP receptor antagonist for the treatment of migraine F Xu, M Zacuto, N Yoshikawa, R Desmond, S Hoerrner, T Itoh, M Journet, ... The Journal of Organic Chemistry 75 (22), 7829-7841, 2010 | 109 | 2010 |
Engineered ribosyl-1-kinase enables concise synthesis of molnupiravir, an antiviral for COVID-19 JA McIntosh, T Benkovics, SM Silverman, MA Huffman, J Kong, ... ACS Central Science 7 (12), 1980-1985, 2021 | 106 | 2021 |
The first large-scale synthesis of MK-4305: a dual orexin receptor antagonist for the treatment of sleep disorder CA Baxter, E Cleator, KMJ Brands, JS Edwards, RA Reamer, FJ Sheen, ... Organic Process Research & Development 15 (2), 367-375, 2011 | 106 | 2011 |
N-Cyclopropylation of Indoles and Cyclic Amides with Copper(II) Reagent T Tsuritani, NA Strotman, Y Yamamoto, M Kawasaki, N Yasuda, T Mase Organic letters 10 (8), 1653-1655, 2008 | 92 | 2008 |
Unlocking the potential of high-throughput experimentation for electrochemistry with a standardized microscale reactor J Rein, JR Annand, MK Wismer, J Fu, JC Siu, A Klapars, NA Strotman, ... ACS Central Science 7 (8), 1347-1355, 2021 | 80 | 2021 |
Catalyst-controlled regioselective Suzuki couplings at both positions of dihaloimidazoles, dihalooxazoles, and dihalothiazoles NA Strotman, HR Chobanian, J He, Y Guo, PG Dormer, CM Jones, ... The Journal of Organic Chemistry 75 (5), 1733-1739, 2010 | 74 | 2010 |
Stereochemistry of cyclopropane formation involving group IV organometallic complexes CP Casey, NA Strotman Journal of the American Chemical Society 126 (6), 1699-1704, 2004 | 61 | 2004 |
Furan Forming Reactions of cis-2-Alken-4-yn-1-ones CP Casey, NA Strotman The Journal of Organic Chemistry 70 (7), 2576-2581, 2005 | 50 | 2005 |
The PPh3-Substituted Hydroxycyclopentadienyl Ruthenium Hydride [2,5-Ph2-3,4-Tol2(η5-C4COH)]Ru(CO)(PPh3)H Is a More Efficient Catalyst for … CP Casey, NA Strotman, SE Beetner, JB Johnson, DC Priebe, TE Vos, ... Organometallics 25 (5), 1230-1235, 2006 | 45 | 2006 |
PPh3-Substituted [2,5-Ph2-3,4-Tol2(η5-C4COH)]Ru(CO)(PPh3)H Exhibits Slower Stoichiometric Reduction, Faster Catalytic Hydrogenation, and Higher … CP Casey, NA Strotman, SE Beetner, JB Johnson, DC Priebe, IA Guzei Organometallics 25 (5), 1236-1244, 2006 | 44 | 2006 |
Dynamic Kinetic Asymmetric Allylation of Hydrazines and Hydroxylamines I Mangion, N Strotman, M Drahl, J Imbriglio, E Guidry Organic Letters 11 (15), 3258-3260, 2009 | 30 | 2009 |
Equilibrium between η2-(o-Ethynylbenzoyl)rhenium Complexes and Rhenium Isobenzofuryl Carbene Complexes and Subsequent Reactions of Isobenzofuryl … CP Casey, NA Strotman, IA Guzei Organometallics 23 (17), 4121-4130, 2004 | 29 | 2004 |
Kilo-Scale Electrochemical Oxidation of a Thioether to a Sulfone: A Workflow for Scaling up Electrosynthesis C Bottecchia, D Lehnherr, F Lévesque, M Reibarkh, Y Ji, VL Rodrigues, ... Organic Process Research & Development 26 (8), 2423-2437, 2022 | 28 | 2022 |