A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses AA Amarilla, JDJ Sng, R Parry, JM Deerain, JR Potter, YX Setoh, ... Nature Communications 12 (1), 3431, 2021 | 97 | 2021 |
SARS-CoV-2 drives NLRP3 inflammasome activation in human microglia through spike protein EA Albornoz, AA Amarilla, N Modhiran, S Parker, XX Li, DK Wijesundara, ... Molecular psychiatry 28 (7), 2878-2893, 2023 | 88 | 2023 |
Synthetic heparan sulfate mimetic pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction SE Guimond, CJ Mycroft-West, NS Gandhi, JA Tree, TT Le, CM Spalluto, ... ACS central science 8 (5), 527-545, 2022 | 78 | 2022 |
Zika virus noncoding RNA suppresses apoptosis and is required for virus transmission by mosquitoes A Slonchak, LE Hugo, ME Freney, S Hall-Mendelin, AA Amarilla, ... Nature Communications 11 (1), 2205, 2020 | 66 | 2020 |
An optimized high-throughput immuno-plaque assay for SARS-CoV-2 AA Amarilla, N Modhiran, YX Setoh, NYG Peng, JDJ Sng, B Liang, ... Frontiers in microbiology 12, 625136, 2021 | 47 | 2021 |
Ancestral SARS-CoV-2, but not Omicron, replicates less efficiently in primary pediatric nasal epithelial cells Y Zhu, KY Chew, M Wu, AC Karawita, G McCallum, LE Steele, ... PLos Biology 20 (8), e3001728, 2022 | 31* | 2022 |
Structural analysis of 3’UTRs in insect flaviviruses reveals novel determinants of sfRNA biogenesis and provides new insights into flavivirus evolution A Slonchak, R Parry, B Pullinger, JDJ Sng, X Wang, TF Buck, FJ Torres, ... Nature Communications 13 (1), 1279, 2022 | 25 | 2022 |
Assessing the potential of unmanned aerial vehicle spraying of aqueous ozone as an outdoor disinfectant for SARS-CoV-2 S Albert, AA Amarilla, B Trollope, JDJ Sng, YX Setoh, N Deering, ... Environmental Research 196, 110944, 2021 | 25 | 2021 |
Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis A Slonchak, X Wang, J Aguado, JDJ Sng, H Chaggar, ME Freney, K Yan, ... Science advances 8 (48), eadd8095, 2022 | 23 | 2022 |
The swan genome and transcriptome, it is not all black and white AC Karawita, Y Cheng, KY Chew, A Challagulla, R Kraus, RC Mueller, ... Genome biology 24 (1), 13, 2023 | 11 | 2023 |
Monoclonal antibodies specific for SARS-CoV-2 spike protein suitable for multiple applications for current variants of concern MS Morgan, K Yan, TT Le, RA Johnston, AA Amarilla, DA Muller, ... Viruses 15 (1), 139, 2022 | 11 | 2022 |
Senolytic therapy alleviates physiological human brain aging and COVID-19 neuropathology J Aguado, AA Amarilla, A Taherian Fard, EA Albornoz, A Tyshkovskiy, ... Nature Aging 3 (12), 1561-1575, 2023 | 9 | 2023 |
A versatile reverse genetics platform for SARS-CoV-2 and other positive-strand RNA viruses. Nat Commun 12: 3431 AA Amarilla, JDJ Sng, R Parry, JM Deerain, JR Potter, YX Setoh, ... | 8 | 2021 |
In vivo inhibition of nuclear ACE2 translocation protects against SARS-CoV-2 replication and lung damage through epigenetic imprinting WJ Tu, M Melino, J Dunn, RD McCuaig, H Bielefeldt-Ohmann, ... Nature Communications 14 (1), 3680, 2023 | 7 | 2023 |
The distinguishing NS5-M114V mutation in American Zika virus isolates has negligible impacts on virus replication and transmission potential NYG Peng, AA Amarilla, LE Hugo, N Modhiran, JDJ Sng, A Slonchak, ... PLoS Neglected Tropical Diseases 16 (5), e0010426, 2022 | 7 | 2022 |
Synthetic Heparan sulfate mimetic Pixatimod (PG545) potently inhibits SARS-CoV-2 by disrupting the spike–ACE2 interaction. ACS Cent Sci 8: 527–545 SE Guimond, CJ Mycroft-West, NS Gandhi, JA Tree, TT Le, CM Spalluto, ... | 6 | 2022 |
A nanobody recognizes a unique conserved epitope and potently neutralizes SARS-CoV-2 omicron variants N Modhiran, SM Lauer, AA Amarilla, P Hewins, SIL van den Broek, ... Iscience 26 (7), 107085, 2023 | 5 | 2023 |
Elevated BMI reduces the humoral response to SARS‐CoV‐2 infection MZW Tong, JDJ Sng, M Carney, L Cooper, S Brown, KE Lineburg, ... Clinical & Translational Immunology 12 (12), e1476, 2023 | 3 | 2023 |
SARS-CoV-2 omicron BA. 5 and XBB variants have increased neurotropic potential over BA. 1 in K18-hACE2 mice and human brain organoids R Stewart, K Yan, SA Ellis, CR Bishop, T Dumenil, B Tang, W Nguyen, ... Frontiers in Microbiology 14, 1320856, 2023 | 2 | 2023 |
TMPRSS2 activation of Omicron lineage Spike glycoprotein is regulated by TMPRSS2 cleavage of ACE2 A Aggarwal, C Fichter, V Milogiannakis, A Akerman, T Ison, MR Silva, ... Biorxiv, 2023.09. 22.558930, 2023 | 2 | 2023 |