S-Glutathiolation by peroxynitrite activates SERCA during arterial relaxation by nitric oxide T Adachi, RM Weisbrod, DR Pimentel, J Ying, VS Sharov, C Schöneich, ... Nature medicine 10 (11), 1200-1207, 2004 | 729 | 2004 |
SOD1 mutations disrupt redox-sensitive Rac regulation of NADPH oxidase in a familial ALS model MM Harraz, JJ Marden, W Zhou, Y Zhang, A Williams, VS Sharov, ... The Journal of clinical investigation 118 (2), 659-670, 2008 | 430 | 2008 |
Methionine oxidation by reactive oxygen species: reaction mechanisms and relevance to Alzheimer's disease C Schöneich Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1703 (2), 111-119, 2005 | 426 | 2005 |
Chemical instability of protein pharmaceuticals: Mechanisms of oxidation and strategies for stabilization S Li, C Schöneich, RT Borchardt Biotechnology and bioengineering 48 (5), 490-500, 1995 | 400 | 1995 |
Oxidative degradation of pharmaceuticals: theory, mechanisms and inhibition SW Hovorka, C Schöneich Journal of pharmaceutical sciences 90 (3), 253-269, 2001 | 342 | 2001 |
Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle RI Viner, DA Ferrington, TD Williams, DJ Bigelow, C Schöneich Biochemical Journal 340 (3), 657-669, 1999 | 342 | 1999 |
Peroxynitrite modification of protein thiols: oxidation, nitrosylation, and S-glutathiolation of functionally important cysteine residue (s) in the sarcoplasmic reticulum Ca-ATPase RI Viner, TD Williams, C Schöneich Biochemistry 38 (38), 12408-12415, 1999 | 307 | 1999 |
Protein instability and immunogenicity: roadblocks to clinical application of injectable protein delivery systems for sustained release W Jiskoot, TW Randolph, DB Volkin, CR Middaugh, C Schöneich, ... Journal of pharmaceutical sciences 101 (3), 946-954, 2012 | 294 | 2012 |
Identification of organic acids and other intermediates in oxidative degradation of chlorinated ethanes on titania surfaces en route to mineralization: a combined … Y Mao, C Schoeneich, KD Asmus The Journal of Physical Chemistry 95 (24), 10080-10089, 1991 | 272 | 1991 |
Proteomic identification of 3-nitrotyrosine-containing rat cardiac proteins: effects of biological aging J Kanski, A Behring, J Pelling, C Schoneich American Journal of Physiology-Heart and Circulatory Physiology 288 (1 …, 2005 | 262 | 2005 |
Reactive oxygen species and biological aging: a mechanistic approach C Schöneich Experimental gerontology 34 (1), 19-34, 1999 | 243 | 1999 |
Free radical reactions of methionine in peptides: mechanisms relevant to β-amyloid oxidation and Alzheimer's disease C Schöneich, D Pogocki, GL Hug, K Bobrowski Journal of the American Chemical Society 125 (45), 13700-13713, 2003 | 227 | 2003 |
Diastereoselective reduction of protein‐bound methionine sulfoxide by methionine sulfoxide reductase VS Sharov, DA Ferrington, TC Squier, C Schöneich FEBS letters 455 (3), 247-250, 1999 | 218 | 1999 |
Nitration and inactivation of tyrosine hydroxylase by peroxynitrite B Blanchard-Fillion, JM Souza, T Friel, GCT Jiang, K Vrana, V Sharov, ... Journal of Biological Chemistry 276 (49), 46017-46023, 2001 | 213 | 2001 |
Loss of conformational stability in calmodulin upon methionine oxidation J Gao, DH Yin, Y Yao, H Sun, Z Qin, C Schöneich, TD Williams, TC Squier Biophysical journal 74 (3), 1115-1134, 1998 | 211 | 1998 |
Proteomic analysis of protein nitration in aging skeletal muscle and identification of nitrotyrosine-containing sequences in vivo by nanoelectrospray ionization tandem mass … J Kanski, SJ Hong, C Schöneich Journal of Biological Chemistry 280 (25), 24261-24266, 2005 | 209 | 2005 |
The Oxidative Inactivation of Sarcoplasmic Reticulum Ca2+-ATPase by Peroxynitrite RI Viner, AFR Hühmer, DJ Bigelow, C Schöneich Free radical research 24 (4), 243-259, 1996 | 207 | 1996 |
Sulfur-centered reactive intermediates in chemistry and biology C Chatgilialoglu, KD Asmus Springer Science & Business Media, 2013 | 201 | 2013 |
Oxidation of therapeutic proteins and peptides: structural and biological consequences R Torosantucci, C Schöneich, W Jiskoot Pharmaceutical research 31, 541-553, 2014 | 200 | 2014 |
Oxidation of polyunsaturated fatty acids and lipids through thiyl and sulfonyl radicals: reaction kinetics, and influence of oxygen and structure of thiyl radicals C Schöneich, U Dillinger, F von Bruchhausen, KD Asmus Archives of biochemistry and biophysics 292 (2), 456-467, 1992 | 177 | 1992 |